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GB901312A - Pyridylcarbamyl lower alkane derivatives and processes for preparing them - Google Patents

Pyridylcarbamyl lower alkane derivatives and processes for preparing them

Info

Publication number
GB901312A
GB901312A GB2554259A GB2554259A GB901312A GB 901312 A GB901312 A GB 901312A GB 2554259 A GB2554259 A GB 2554259A GB 2554259 A GB2554259 A GB 2554259A GB 901312 A GB901312 A GB 901312A
Authority
GB
United Kingdom
Prior art keywords
carbon atom
carbamoyl
substituted
carbamoyloxy
nitrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2554259A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Irwin Neisler and Co
Original Assignee
Irwin Neisler and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irwin Neisler and Co filed Critical Irwin Neisler and Co
Publication of GB901312A publication Critical patent/GB901312A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises mono-N-substituted-carbamoyl-lower-alkanes having a hydroxy, lower-alkanoyloxy, carbamoyloxy or N-mono- or di-lower-alkyl-carbamoyloxy group attached to a carbon atom of the alkane chain, which carbon atom is separated from the carbamoyl nitrogen atom by at least the carbonyl group and carries also at least one monocarbocyclic group, optionally substituted by halogens or lower alkyl or alkoxy groups, the N-substituent being a pyridyl residue joined to the carbamoyl nitrogen atom through a carbon atom of the pyridine ring, which may carry one or more simple substituents not adversely affecting the pharmacological properties of the compound (e.g. halogen, methyl, methoxy, nitro or trifluoromethyl), and the term "lower" denoting the presence of not more than 4 carbon atoms, and their acid addition and quaternary ammonium salts, and the preparation thereof by reacting an appropriate aminopyridine with an appropriately substituted lower alkanoic acid or a lower alkyl ester or acid chloride thereof. The products possess analgesic and central nervous system depressant properties. Specification 901,311 is referred to.
GB2554259A 1958-11-04 1959-07-24 Pyridylcarbamyl lower alkane derivatives and processes for preparing them Expired GB901312A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77173758A 1958-11-04 1958-11-04

Publications (1)

Publication Number Publication Date
GB901312A true GB901312A (en) 1962-07-18

Family

ID=25092813

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2554259A Expired GB901312A (en) 1958-11-04 1959-07-24 Pyridylcarbamyl lower alkane derivatives and processes for preparing them

Country Status (2)

Country Link
CH (1) CH391701A (en)
GB (1) GB901312A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2597865A1 (en) * 1986-04-29 1987-10-30 Roussel Uclaf New derivatives of a benzylalkylcarboxylic acid substituted with a 4-pyridylaminocarbonyl radical, process for their preparation, the new intermediates obtained, their application as medicaments and the pharmaceutical compositions which contain them
US5583147A (en) * 1994-03-23 1996-12-10 The Dupont Merck Pharmaceutical Company Amides for the treatment of atherosclerosis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2597865A1 (en) * 1986-04-29 1987-10-30 Roussel Uclaf New derivatives of a benzylalkylcarboxylic acid substituted with a 4-pyridylaminocarbonyl radical, process for their preparation, the new intermediates obtained, their application as medicaments and the pharmaceutical compositions which contain them
US5583147A (en) * 1994-03-23 1996-12-10 The Dupont Merck Pharmaceutical Company Amides for the treatment of atherosclerosis

Also Published As

Publication number Publication date
CH391701A (en) 1965-05-15

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