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Expired
Application number
GB17925/58A
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BASF Schweiz AG
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Ciba AG
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Application filed by Ciba AGfiledCriticalCiba AG
Publication of GB862390ApublicationCriticalpatent/GB862390A/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
The invention comprises methyl 18-0-(acylaminobenzoyl) reserpates and their salts, together with processes for their preparation wherein methyl reserpate is esterified with a benzoic acid which is substituted by an acylamino group or a subtituent convertible into such a group, e.g. nitro, amino, and such substitutent if present is converted into an acylamino group, and if desired, a base so obtained is converted into a salt thereof or the resulting salt converted into the free base. Examples detail the preparation of methyl 18-0-benzoyl reserpates substituted in the benzene nucleus by 31- and 41-ethoxyformamido-, 31- and 41-acetylamino-, 31, 51-diacetylamino-, 31, 51-diethoxyformamido- and 41-phenylureidogroups. Methyl 18-0-(41-aminobenzoyl) reserpate is prepared by catalytic hydrogenation of the 41-nitro analogue, itself prepared by esterification of methyl reserpate with 4-nitrobenzoyl chloride. Specification 744,290 is referred to.
GB17925/58A1957-06-041958-06-04New reserpic acid derivatives and process for their manufacture
ExpiredGB862390A
(en)
Procedure for the preparation of some derivatives of dialkilditiofosforic acids with a double amid function in the molecule (Machine-translation by Google Translate, not legally binding)
Process for the preparation of aromatic carboxylic acid esters of N- (β-hydroxyethyl) -N '- [γ- (3'-chloro-10'-phenthiazinyl) -propyl] -piperazine or acid addition salts thereof.
Process for the preparation of aromatic carboxylic acid esters of N- (β-hydroxyethyl) -N '- [γ- (3'-chloro-10'-phenthiazinyl) -propyl] -piperazine or salts thereof.