GB824598A - Improvements in or relating to new phenthiazine derivatives and processes for their preparation - Google Patents
Improvements in or relating to new phenthiazine derivatives and processes for their preparationInfo
- Publication number
- GB824598A GB824598A GB4810/58A GB481058A GB824598A GB 824598 A GB824598 A GB 824598A GB 4810/58 A GB4810/58 A GB 4810/58A GB 481058 A GB481058 A GB 481058A GB 824598 A GB824598 A GB 824598A
- Authority
- GB
- United Kingdom
- Prior art keywords
- preparation
- formula
- relating
- processes
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
- C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
The invention comprises compounds of the formula <FORM:0824598/IV (b)/1> and their acid addition and quaternary ammonium salts (wherein R is a hydrogen atom or acetyl group, R1 is a hydrogen atom or methyl group, and X is a methanesulphonyl or dimethylsulphamoyl group), and the preparation thereof by: (1) reacting a phenthiazine of the formula <FORM:0824598/IV (b)/2> with a reactive ester of the formula Y-CH2-CH2-O-CH2-CH2-OR (wherein Y is the acid residue of a reactive ester, e.g. a halogen atom or a sulphuric or sulphonic ester residue); (2) when R is an acetyl group, acetylating a corresponding phenthiazine in which R is a hydrogen atom. Other general methods for making the compounds of the invention are described.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR824598X | 1957-02-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB824598A true GB824598A (en) | 1959-12-02 |
Family
ID=9281893
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB4810/58A Expired GB824598A (en) | 1957-02-14 | 1958-02-13 | Improvements in or relating to new phenthiazine derivatives and processes for their preparation |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB824598A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3264290A (en) * | 1963-02-28 | 1966-08-02 | Squibb & Sons Inc | Basic ethers of hydroxyethylpiperazinopropylphenothiazines |
EP2061788A4 (en) * | 2006-09-01 | 2010-10-06 | Immune Control Inc | Novel compositions and methods for treatment of diseases related to activated lymphocytes |
US7893077B2 (en) | 2004-08-12 | 2011-02-22 | Amgen Inc. | Bisaryl-sulfonamides |
-
1958
- 1958-02-13 GB GB4810/58A patent/GB824598A/en not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3264290A (en) * | 1963-02-28 | 1966-08-02 | Squibb & Sons Inc | Basic ethers of hydroxyethylpiperazinopropylphenothiazines |
US7893077B2 (en) | 2004-08-12 | 2011-02-22 | Amgen Inc. | Bisaryl-sulfonamides |
EP2061788A4 (en) * | 2006-09-01 | 2010-10-06 | Immune Control Inc | Novel compositions and methods for treatment of diseases related to activated lymphocytes |
US7923445B2 (en) | 2006-09-01 | 2011-04-12 | Immune Control, Inc. | Methods for treatment of diseases related to activated lymphocytes |
US7981885B2 (en) | 2006-09-01 | 2011-07-19 | Immune Control Inc. | Compositions for treatment of diseases related to activated lymphocytes |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB836854A (en) | New imidazole derivatives and processes for their preparation | |
ES483767A1 (en) | PROCEDURE FOR PRODUCING N-ARYLSULFONYL-L-ARGININAMIDES | |
GB828393A (en) | New phenthiazine derivatives and processes for their preparation | |
GB824598A (en) | Improvements in or relating to new phenthiazine derivatives and processes for their preparation | |
GB831920A (en) | New phenthiazine derivatives and processes for their preparation | |
GB824536A (en) | Improvements in or relating to new phenthiazine derivatives and processes for their preparation | |
GB823191A (en) | New phenthiazine derivatives and processes for their preparation | |
GB986579A (en) | 5-ethylidene dibenzocycloheptadienes and the preparation thereof | |
GB904242A (en) | Homopiperazino derivatives and a process for their production | |
GB873316A (en) | Optically active 3-mercapto-phenthiazine derivatives | |
GB778936A (en) | Improvements relating to n-aminoalkyl derivatives of substituted iminodibenzyls | |
GB2001974A (en) | Vincinic acid derivatives and process for the preparation thereof | |
GB1094810A (en) | Unsaturated 4,5-seco-steroid compounds, and processes for their preparation | |
GB893923A (en) | Movements in or relating to steroids and the manufacture thereof | |
GB837840A (en) | Reserpic acid esters and salts thereof and process for their manufacture | |
CH376505A (en) | Process for the preparation of basic phenothiazine derivatives which are substituted in the 3-position by a monovalent sulfur function | |
GB806079A (en) | 4-aziridino-1, 2-naphthoquinones | |
GB834370A (en) | Phenothiazine derivatives | |
ES271353A1 (en) | Improvements in or relating to the production of esterified amino-alcohols | |
GB791409A (en) | 5-chloro-8-acetoxyquinoline and germicidal compositions thereof | |
GB837947A (en) | Reserpic acid esters and salts thereof and process for their manufacture | |
FR1168732A (en) | Process for the preparation of cholenic acid derivatives | |
GB965929A (en) | Novel steroid compounds and their production | |
GB761529A (en) | Steroid compounds | |
GB857418A (en) | Process for the manufacture of basically substituted 3-alkyl-phenothiazines |