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GB824598A - Improvements in or relating to new phenthiazine derivatives and processes for their preparation - Google Patents

Improvements in or relating to new phenthiazine derivatives and processes for their preparation

Info

Publication number
GB824598A
GB824598A GB4810/58A GB481058A GB824598A GB 824598 A GB824598 A GB 824598A GB 4810/58 A GB4810/58 A GB 4810/58A GB 481058 A GB481058 A GB 481058A GB 824598 A GB824598 A GB 824598A
Authority
GB
United Kingdom
Prior art keywords
preparation
formula
relating
processes
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4810/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Societe des Usines Chimiques Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc SA, Societe des Usines Chimiques Rhone Poulenc SA filed Critical Rhone Poulenc SA
Publication of GB824598A publication Critical patent/GB824598A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/141,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18[b, e]-condensed with two six-membered rings
    • C07D279/22[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

The invention comprises compounds of the formula <FORM:0824598/IV (b)/1> and their acid addition and quaternary ammonium salts (wherein R is a hydrogen atom or acetyl group, R1 is a hydrogen atom or methyl group, and X is a methanesulphonyl or dimethylsulphamoyl group), and the preparation thereof by: (1) reacting a phenthiazine of the formula <FORM:0824598/IV (b)/2> with a reactive ester of the formula Y-CH2-CH2-O-CH2-CH2-OR (wherein Y is the acid residue of a reactive ester, e.g. a halogen atom or a sulphuric or sulphonic ester residue); (2) when R is an acetyl group, acetylating a corresponding phenthiazine in which R is a hydrogen atom. Other general methods for making the compounds of the invention are described.
GB4810/58A 1957-02-14 1958-02-13 Improvements in or relating to new phenthiazine derivatives and processes for their preparation Expired GB824598A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR824598X 1957-02-14

Publications (1)

Publication Number Publication Date
GB824598A true GB824598A (en) 1959-12-02

Family

ID=9281893

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4810/58A Expired GB824598A (en) 1957-02-14 1958-02-13 Improvements in or relating to new phenthiazine derivatives and processes for their preparation

Country Status (1)

Country Link
GB (1) GB824598A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3264290A (en) * 1963-02-28 1966-08-02 Squibb & Sons Inc Basic ethers of hydroxyethylpiperazinopropylphenothiazines
EP2061788A4 (en) * 2006-09-01 2010-10-06 Immune Control Inc Novel compositions and methods for treatment of diseases related to activated lymphocytes
US7893077B2 (en) 2004-08-12 2011-02-22 Amgen Inc. Bisaryl-sulfonamides

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3264290A (en) * 1963-02-28 1966-08-02 Squibb & Sons Inc Basic ethers of hydroxyethylpiperazinopropylphenothiazines
US7893077B2 (en) 2004-08-12 2011-02-22 Amgen Inc. Bisaryl-sulfonamides
EP2061788A4 (en) * 2006-09-01 2010-10-06 Immune Control Inc Novel compositions and methods for treatment of diseases related to activated lymphocytes
US7923445B2 (en) 2006-09-01 2011-04-12 Immune Control, Inc. Methods for treatment of diseases related to activated lymphocytes
US7981885B2 (en) 2006-09-01 2011-07-19 Immune Control Inc. Compositions for treatment of diseases related to activated lymphocytes

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