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GB781407A - New quaternary amino ethers - Google Patents

New quaternary amino ethers

Info

Publication number
GB781407A
GB781407A GB2928155A GB2928155A GB781407A GB 781407 A GB781407 A GB 781407A GB 2928155 A GB2928155 A GB 2928155A GB 2928155 A GB2928155 A GB 2928155A GB 781407 A GB781407 A GB 781407A
Authority
GB
United Kingdom
Prior art keywords
general formula
amino
reacted
diethylaminoethyl
halide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2928155A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SAPOS LAB
Original Assignee
SAPOS LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SAPOS LAB filed Critical SAPOS LAB
Priority to GB2928155A priority Critical patent/GB781407A/en
Publication of GB781407A publication Critical patent/GB781407A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises quaternary amino-ethers of the general formula <FORM:0781407/IV (a)/1> wherein X represents a halogen atom, and the preparation thereof by reacting at an elevated temperature an amino-alkoxide of the general formula <FORM:0781407/IV (a)/2> with a diethylaminoethyl halide of the general formula <FORM:0781407/IV (a)/3> wherein M represents an alkali metal and Y represents a halogen atom, and the tertiary amino-ether thus obtained is reacted with approximately two molecular proportions of a methyl halide. The reaction with the amino-alkoxide may be carried out at a temperature within the range of 150 DEG to 250 DEG C. The reaction with the methyl halide is preferably carried out in an inert organic solvent, e.g. methanol. In an example, the sodium salt of b -pyrrolidino-ethanol is reacted with diethylaminoethyl chloride to form the b -(N-pyrrolidinyl)-ethyl b 1-diethylaminoethyl ether which is then reacted with methyl iodide to form the diodide of N-diethylmethylammonium-ethoxyethyl - N1 - methylpyrrolidine of the above general formula wherein X represents iodine.
GB2928155A 1955-10-14 1955-10-14 New quaternary amino ethers Expired GB781407A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2928155A GB781407A (en) 1955-10-14 1955-10-14 New quaternary amino ethers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2928155A GB781407A (en) 1955-10-14 1955-10-14 New quaternary amino ethers

Publications (1)

Publication Number Publication Date
GB781407A true GB781407A (en) 1957-08-21

Family

ID=10289053

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2928155A Expired GB781407A (en) 1955-10-14 1955-10-14 New quaternary amino ethers

Country Status (1)

Country Link
GB (1) GB781407A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993001178A1 (en) * 1991-07-12 1993-01-21 Buckman Laboratories International, Inc. Diaminic compounds, preparation, use and intermediates

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993001178A1 (en) * 1991-07-12 1993-01-21 Buckman Laboratories International, Inc. Diaminic compounds, preparation, use and intermediates
US5268470A (en) * 1991-07-12 1993-12-07 Buckman Laboratories Internation, Inc. Diamine compounds, method of making same, method of use of same and intermediates
AU653304B2 (en) * 1991-07-12 1994-09-22 Buckman Laboratories International, Inc. Diaminic compounds, preparation, use and intermediates
EP0705825A2 (en) * 1991-07-12 1996-04-10 Buckman Laboratoires International, Inc. Diaminic compounds, preparation, use and intermediates
EP0705825A3 (en) * 1991-07-12 1996-04-24 Buckman Labor Inc

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