GB759624A - Cephalosporin production - Google Patents
Cephalosporin productionInfo
- Publication number
- GB759624A GB759624A GB28522/53A GB2852253A GB759624A GB 759624 A GB759624 A GB 759624A GB 28522/53 A GB28522/53 A GB 28522/53A GB 2852253 A GB2852253 A GB 2852253A GB 759624 A GB759624 A GB 759624A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cephalosporin
- medium
- methionine
- meal
- mould
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Botany (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
A fermentation medium for use in the production of Cephalosporin-N, or mixtures of Cephalosporin-N and Cephalosporin-P, from a Cephalosporin-producing-mould of the species of which Cephalosporium I.M.I. 49137 is a member, comprises a nutritional substrate for said mould in admixture with an active proportion (defined) of d-methionine. Racemic d-l-methionine may also be used, the quantity required being twice that of the d-isomer alone. For Cephalosporin-N and a corn steep liquor, sucrose, ammonium acetate medium, the optimum concentration of d-methionine is 0.025 to 0.05 per cent by weight of the medium. The d-methionine requirement of the mould varies with the medium. The preferred medium is that disclosed in co-pending Specification 745,208. Normally minimum requirements are a source of nitrogen and a source of carbohydrate. It is preferred that the medium contains a source of organic nitrogen, e.g. fish meal, meat meal, casein, bouillon powder, dried autolysed yeast, malt extract, urea, soya bean meal, corn meal and corn steep liquor. Media containing d-methionine are less effective in the production of increasing yields of Cephalosporin-P than in the case of Cephalosporin-N.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB28522/53A GB759624A (en) | 1953-10-15 | 1953-10-15 | Cephalosporin production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB28522/53A GB759624A (en) | 1953-10-15 | 1953-10-15 | Cephalosporin production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB759624A true GB759624A (en) | 1956-10-24 |
Family
ID=10276960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB28522/53A Expired GB759624A (en) | 1953-10-15 | 1953-10-15 | Cephalosporin production |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB759624A (en) |
-
1953
- 1953-10-15 GB GB28522/53A patent/GB759624A/en not_active Expired
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