GB716230A - New phenthiazine derivatives and processes for their preparation - Google Patents
New phenthiazine derivatives and processes for their preparationInfo
- Publication number
- GB716230A GB716230A GB658154A GB658154A GB716230A GB 716230 A GB716230 A GB 716230A GB 658154 A GB658154 A GB 658154A GB 658154 A GB658154 A GB 658154A GB 716230 A GB716230 A GB 716230A
- Authority
- GB
- United Kingdom
- Prior art keywords
- processes
- preparation
- phenthiazine derivatives
- new phenthiazine
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical class C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 title 1
- HDDNBUNZJIQDBQ-UHFFFAOYSA-N 1-(3-chloropropyl)piperidine Chemical compound ClCCCN1CCCCC1 HDDNBUNZJIQDBQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- ODZPKZBBUMBTMG-UHFFFAOYSA-N sodium amide Chemical compound [NH2-].[Na+] ODZPKZBBUMBTMG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
- C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
- C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The invention comprises 3-chloro-10-piperidinopropyl-phenthiazine, obtainable by the action of 1 - piperidino - 3 - chloropropane on 3-chlorophenthiazine in presence of sodamide. The product is employed in the form of acid addition or quaternary salts.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB658154A GB716230A (en) | 1953-06-29 | 1953-06-29 | New phenthiazine derivatives and processes for their preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB658154A GB716230A (en) | 1953-06-29 | 1953-06-29 | New phenthiazine derivatives and processes for their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
GB716230A true GB716230A (en) | 1954-09-29 |
Family
ID=9817100
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB658154A Expired GB716230A (en) | 1953-06-29 | 1953-06-29 | New phenthiazine derivatives and processes for their preparation |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB716230A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1100635B (en) * | 1958-04-22 | 1961-03-02 | Rhone Poulenc Sa | Process for the preparation of phenthiazine derivatives |
DE1117584B (en) * | 1957-10-21 | 1961-11-23 | Rhone Poulenc Sa | Process for the preparation of phentiazine derivatives |
DE1137025B (en) * | 1959-05-08 | 1962-09-27 | Rhone Poulenc Sa | Process for the preparation of phenthiazine derivatives |
US20220008420A1 (en) * | 2016-07-13 | 2022-01-13 | The Children's Medical Center Corporation | Calmodulin inhibitors, chk2 inhibitors and rsk inhibitors for the treatment of ribosomal disorders and ribosomapathies |
-
1953
- 1953-06-29 GB GB658154A patent/GB716230A/en not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1117584B (en) * | 1957-10-21 | 1961-11-23 | Rhone Poulenc Sa | Process for the preparation of phentiazine derivatives |
DE1100635B (en) * | 1958-04-22 | 1961-03-02 | Rhone Poulenc Sa | Process for the preparation of phenthiazine derivatives |
DE1137025B (en) * | 1959-05-08 | 1962-09-27 | Rhone Poulenc Sa | Process for the preparation of phenthiazine derivatives |
US20220008420A1 (en) * | 2016-07-13 | 2022-01-13 | The Children's Medical Center Corporation | Calmodulin inhibitors, chk2 inhibitors and rsk inhibitors for the treatment of ribosomal disorders and ribosomapathies |
US11944625B2 (en) * | 2016-07-13 | 2024-04-02 | The Children's Medical Center Corporation | Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the treatment of ribosomal disorders and ribosomapathies |
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