GB622559A - Improvements in or relating to a process of producing diphenylacetonitrile and the product resulting therefrom - Google Patents
Improvements in or relating to a process of producing diphenylacetonitrile and the product resulting therefromInfo
- Publication number
- GB622559A GB622559A GB8275/47A GB827547A GB622559A GB 622559 A GB622559 A GB 622559A GB 8275/47 A GB8275/47 A GB 8275/47A GB 827547 A GB827547 A GB 827547A GB 622559 A GB622559 A GB 622559A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzene
- benzaldehyde
- cyanhydrin
- etherate
- diphenylacetonitrile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Diphenylacetonitrile is produced by reacting benzaldehyde cyanhydrin with benzene in the presence of boron trifluoride or an etherate thereof. Benzaldehyde may be reacted with an equivalent of hydrogen cyanide, the reaction product dissolved in benzene, and treated with boron trifluoride or an etherate. The product may be treated with water, the aqueous phase removed, and the nitrile recovered from the benzene phase. The hydrogen cyanide preferably contains about 1 per cent or less of benzaldehyde cyanhydrin and/or an aqueous solution of sodium cyanide. Temperatures are preferably about 35-40 DEG C. for production of the cyanhydrin and 60-70 DEG C. for reaction thereof with benzene. Excess of boron trifluoride may be used either as such or, for example, as the ethyl or di-isopropyl etherate. In an example, to liquid hydrogen cyanide mixed with saturated aqueous sodium cyanide and benzaldehyde cyanhydrin, benzaldehyde is added with cooling to maintain a temperature of 30 DEG rising to 50 DEG C. Four equivalents of benzene are added, and 1.5 equivalents of boron fluoride passed in while cooling to about 50-70 DEG C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US622559XA | 1946-07-15 | 1946-07-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB622559A true GB622559A (en) | 1949-05-04 |
Family
ID=22041251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8275/47A Expired GB622559A (en) | 1946-07-15 | 1947-03-26 | Improvements in or relating to a process of producing diphenylacetonitrile and the product resulting therefrom |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB622559A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103351311A (en) * | 2013-06-17 | 2013-10-16 | 张家港威胜生物医药有限公司 | Synthesis method of diphenylacetonitrile |
-
1947
- 1947-03-26 GB GB8275/47A patent/GB622559A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103351311A (en) * | 2013-06-17 | 2013-10-16 | 张家港威胜生物医药有限公司 | Synthesis method of diphenylacetonitrile |
| CN103351311B (en) * | 2013-06-17 | 2016-05-11 | 张家港威胜生物医药有限公司 | A kind of synthetic method of diphenatril |
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