Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB13242/45A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Societe des Usines Chimiques Rhone Poulenc SA
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Filing date
Publication date
Application filed by Rhone Poulenc SA, Societe des Usines Chimiques Rhone Poulenc SAfiledCriticalRhone Poulenc SA
Publication of GB606182ApublicationCriticalpatent/GB606182A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Therapeutic compounds of the general formula <FORM:0606182/IV(b)/1> (wherein R represents an alkyl group) are manufactured by condensing N-(b -dimethylaminoethyl)-2-aminopyridine or its sodio derivative with an alkyl ether of the chlorhydrin of ethylene glycol. In an example, N-(b -dimethylaminoethyl)-2-aminopyridine is treated with sodamide in toluene and the product is heated with b -ethoxyethyl chloride to produce N-(b -dimethylaminoethyl) - N - (b 1-ethoxyethyl) - 2 - aminopyridine. The Specification as open to inspection under Sect. 91 comprises also the manufacture of similar compounds in which R may represent an aralkyl group and the alkylene chain connecting the two tertiary amino groups may consist of more than two methylene groups, which may carry alkyl substituents; and an alternative method of preparation consisting in condensing an alkoxy- or aralkoxy-ethylaminopyridine with an o -halogenated tertiary amine (CH3)2N-(CR1R2)n-X (wherein X represents a halogen atom, R1 and R2 represent hydrogen atoms or alkyl groups and n is an integer equal to or greater than 2). This subject-matter does not appear in the Specification as accepted.
GB13242/45A1944-01-191945-05-26Improvements in or relating to the preparation of substituted diamines
ExpiredGB606182A
(en)
Procedure for the preparation of new compounds of 1,4-benzodioxane and 1,5-benzodioxepane (Machine-translation by Google Translate, not legally binding)