GB2629216A - Compositions containing synergistic combination of quaternary ammonium compounds and select polymers - Google Patents

Abstract

Disinfecting composition comprising at least approximately 0.00001 % wt of a benzyl-substituted quaternary ammonium compound (e.g. BKC), and a polymer selected from the group consisting of poly(diallyldimethylammonium chloride) (PQ6) having a molecular weight <100kDa (PQ6 <100kDa); PQ6 having a molecular weight ranging from 200kDa to 300 kDa (PQ6 200-300kDa); PQ6 having a molecular weight ranging from 400 kDa to 500 kDa (PQ6 400-500 kDa); copolymers of vinylpyrrolidone (VP) and quaternized vinylimidazole (QVI)(PQ16) having 5%wt VP and 95% wt QVI (PQ16 5VP-95QVI); PQ16 having 50%wt VP and 95% wt QVI (PQ16 50VP-50QVI); Poly(2-dimethylamino)ethyl methacrylate) methyl chloride quaternary salt (PQ37); 1-propanaminium, N,N,N-trimethyl-3-[(1-oxo-2-propenyl)amino] chloride, homopolymer (A1000); 1-dodecanaminium, N,N15 dimethyl-N-[3-[(2-methyl-1-oxo-2-propen-1-yl)amino]propyl]-, chloride (1:1), polymer with sodium 2-methyl-2-[(1-oxo-2-propen-1-yl)amino]-1-propanesulfonate (1:1) and N,N,N-trimethyl-3-[(1-oxo-2-propen-1-yl)amino]-L propanaminium chloride (1:1) (C113); and combinations thereof. The polymers may act synergistically with the benzyl-substituted ammonium compound. Also claimed is a method of increasing disinfection activity as defined herein.

Description

Intellectual Property Office Application No GI32306664.0 RTM Date:20 October 2023 The following terms are registered trade marks and should be read as such wherever they occur in this document: Supracare Cellosize, Coltide Ecothix Cellulon Luviquat Chromohance Ammonyx Gafquat N-Durhance Protectol Dowanol Rewoquat Cellosolve Natrosol Mackadet Cellulon Intellectual Property Office is an operating name of the Patent Office www.gov.uk /ipo

COMPOSITIONS CONTAINING SYNERGISTIC COMBINATION OF QUATERNARY AMMONIUM COMPOUNDS AND SELECT POLYMERS

Cross Reference to Related Applications

This application claims priority to US provisional patent application number 63/497,483, filed 21 April 2023, the contents of which are incorporated herein by reference in its entirety.

Technical Field

Disinfecting compositions are disclosed comprising a synergistic combination of a benzyl-substituted quaternary ammonium compound and specified polymers. The specified polymers increase the disinfection activity of the benzyl-substituted quaternary ammonium compound in the disinfecting composition.

Background

Industry leaders have predominantly utilized quaternary ammonium compounds (quats) in order to provide consumers with a germ kill benefit. Quats are typically cheap, readily available, and offer a satisfactory level of disinfection to the consumer. Despite these benefits, quats are known to be toxic to aquatic environments with potential long-lasting effects. Even though quats are expected to biodegrade, regulatory bodies (e.g., the US Environmental Protection Agency) may prohibit individuals from making biodegradability claims if these compounds are present in any amount.

W02023/036940 to Rhodia Operations discloses an antimicrobial composition comprising a first antimicrobial agent selected from the group consisting of benzalkonium salts, trilocarban, diclosan, triclosan, or combinations thereof, and a second antimicrobial agent which is a cationic polymer (known as polyquaternium 2) having a weight average molecular weight of 1,000 to 50,000 represented by the general formula (0: US2022/233411 to Godrej Consumer Products Ltd discloses a reconstitutable sanitizer formulation which is non-alcoholic in nature and achieves up to 99.9% reduction in microbial load and provides long-lasting protection against microbes for 2-6 hours.

W02020/168046 to Rhodia Operations discloses microbial compositions that include an antimicrobial component having at least one quaternary ammonium compound; a synthetic polymer, such as PQ5, PQ7, PQ11, or PQ28; an organic acid; a surfactant selected from cationic surfactants, amphoteric surfactants, and combinations thereof; and at least one non-ionic surfactant.

W02013/124784 to BASF (China) Company Limited discloses compositions comprising a) an antimicrobial agent selected from the group consisting of biocides containing halogen atoms and/or containing phenolic moieties, formic acid, chlorine dioxide, chlorine dioxide generating compounds, dialdehydes, components containing an antimicrobial metal, such as antimicrobial metal, and b) a polymine, especially polyethyleneimine.

W02012/090100 to Kimberly-Clark Worldwide, Inc. discloses durable antimicrobial compositions comprising a carbonate/bicarbonate salt of a quaternary ammonium cation, an organic acid, hydrogen peroxide and a cationic polymer, namely (3-acrylamidopropyl)trimethylammonium chloride monomer combined with another monomer).

W02001/030951 to Reckitt & Colman France discloses laundry compositions comprising one or more quaternary ammonium polymers, effective as a textile conditioner on a range of textile materials.

A need remains for disinfecting compositions with low levels of quats.

Summary of Invention

Disclosed are disinfecting composition comprising at least approximately 0.00001 % wt of a benzyl-substituted quaternary ammonium compound, and a polymer selected from the group consisting of poly(diallyldimethylammonium chloride) (PQ6) having a molecular weight <100kDa (PQ6 <100kDa); PQ6 having a molecular weight ranging from 200kDa to 300 kDa (PQ6 200-300kDa); PQ6 having a molecular weight ranging from 400 kDa to 500 kDa (PQ6 400-500 kDa); copolymers of vinylpyrrolidone (VP) and quaternized vinylimidazole (QVI)(PQ16) having 5%wt VP and 95% wt QVI (PQ16 5VP-950V0; PQ16 having 50%wt VP and 95% wt QVI (PQ16 50VP-500V1); Poly(2-dimethylamino)ethyl methacrylate) methyl chloride quaternary salt (PQ37); 1-propanaminium, N,N,N- trimethy1-3-[(1-oxo-2-propenyl)amino] chloride, homopolymer (A1000); 1- dodecanaminium, N,N-dimethyl-N-[3-[(2-methy1-1-oxo-2-propen-1-yl)amino]propyll-, chloride (1:1), polymer with sodium 2-methy1-2-[(1 -oxo-2-propen-1-yl)amino]-1-propanesulfonate (1:1) and N,N,N-trimethy1-3-[(1-oxo-2-propen-1-yhamino]-L propanaminium chloride (1:1) (C113); and combinations thereof. The disclosed disinfecting compositions may include one or more of the following aspects: * the disinfecting composition comprising approximately 0.05% wt to approximately 0.2% wt of the benzyl-substituted quaternary ammonium compound and approximately 0.01% wt to approximately 0.1% wt of the polymer and the disinfecting composition is an all-purpose cleaner; * the disinfecting composition comprising approximately 0.3% wt to approximately 1.5% wt of the benzyl-substituted quaternary ammonium compound and approximately 0.06% wt to approximately 0.5% wt of the polymer and the disinfecting composition is a dilutable all-purpose cleaner; * the disinfecting composition comprising approximately 2% wt to approximately 4% wt of the benzyl-substituted quaternary ammonium compound and approximately 0.08% wt to approximately 0.5% wt of the polymer and the disinfecting composition is a laundry sanitizer; * the disinfecting composition comprising approximately 1% wt to approximately 2% wt dialkyl dimethyl ammonium chloride, approximately 0.4% wt to approximately 0.75% wt benzyl-substituted quaternary ammonium compound, and approximately 0.08% to approximately 0.15% the polymer and the disinfecting composition is a laundry sanitizer; * the disinfecting composition comprising approximately 1.25% wt to approximately 3.3% wt of the benzyl-substituted quaternary ammonium compound, approximately 0.25% wt to approximately 4% wt of the polymer, and approximately 4%wt to approximately 6% wt citric acid, and the disinfecting composition is a laundry sanitizer; * the disinfecting composition comprising approximately 2% wt to approximately 6% wt of the benzyl-substituted quaternary ammonium compound and approximately 0.25% wt to approximately 4% wt of the polymer and the disinfecting composition is a laundry sanitizer; * the disinfecting composition comprising a reduced concentration of the benzyl-substituted quaternary ammonium compound as compared to a concentration of the benzyl-substituted quaternary ammonium compound in a first comparative disinfecting composition comprising the benzyl-substituted quaternary ammonium compound alone; * the concentration of the benzyl-substituted quaternary ammonium compound being reduced by fifty percent or more as compared to a concentration of the benzylsubstituted quaternary ammonium compound in a first comparative disinfecting composition comprising the benzyl-substituted quaternary ammonium compound alone; * the disinfecting composition comprising a reduced concentration of the polymer as compared to a concentration of the polymer in a second comparative disinfecting composition comprising the polymer alone; * the polymer being PQ6 <100kDa, PQ6 200-300 kDa, PQ6 400-500 kDa, PQ16 5VP95QVI, A1000, C113, or combinations thereof; * the polymer being PQ6 <100kDa, PQ6 200-300 kDa, or combinations thereof; * the polymer being PQ6 <100kDa; * the polymer being PQ6 200-300 kDa; * the polymer being PQ6 400-500 kDa; * the polymer being PQ16 5VP-95QVI; * the polymer being PQ16 50VP-50QVI; * the polymer being PQ37; * the polymer being A1000; * the polymer being C113; * the composition being substantially free of a polymer selected from the group consisting of poly(acrylamide-co-diallyldimethylammonium chloride (PQ7), copolymers of vinylpyrrolidone and quaternized vinylimidazole having more vinylpyrrolidone units than quaternized vinylimidazole units (PQ16 70VP-30QVI), 2-pyrrolidinone, 1-ethenyl-polymer with N,N,N-trimethy1-3-[(2-methyl-1-oxo-2-propenyl)amino]-1-propanium chloride (PQ28), and combinations thereof; * the composition being a laundry composition; * the laundry composition being a biocide; * the laundry composition being a sanitizer; * the laundry composition being a softener; * the laundry composition being a conditioner; * the laundry composition being a fabric protector; * the laundry composition being a fabric protector and biocide; * the laundry composition being a fabric protector and sanitizer; * the laundry composition being a conditioner and biocide; * the laundry composition being a conditioner and sanitizer; * the laundry composition being a softener and biocide; * the laundry composition being a softener and sanitizer; * the composition being an all-purpose cleaner; * the composition being a hard surface disinfectant; * the composition being a soft surface disinfectant; * the laundry composition comprising only one benzyl-substituted quaternary ammonium compound; * the benzyl-substituted quaternary ammonium compound being C12-18 alkyl dimethyl benzyl ammonium chloride; * the benzyl-substituted quaternary ammonium compound being C12-16 alkyl dimethyl benzyl ammonium chloride; * the concentration of the benzyl-substituted quaternary ammonium compound being approximately 5% wt to approximately 50% wt less than the concentration of the benzyl-substituted quaternary ammonium compound in the first comparative disinfecting composition; * the concentration of the benzyl-substituted quaternary ammonium compound being approximately 6% wt to approximately 40% wt less than the concentration of the benzyl-substituted quaternary ammonium compound in the first comparative disinfecting composition; * the concentration of the benzyl-substituted quaternary ammonium compound being approximately 7% wt to approximately 30% wt less than the concentration of the benzyl-substituted quaternary ammonium compound in the first comparative disinfecting composition; * the concentration of the benzyl-substituted quaternary ammonium compound being approximately 8% wt to approximately 20% wt less than the concentration of the benzyl-substituted quaternary ammonium compound in the first comparative disinfecting composition; * the concentration of the benzyl-substituted quaternary ammonium compound being approximately 9% wt to approximately 15% wt less than the concentration of the benzyl-substituted quaternary ammonium compound in the first comparative disinfecting composition; * further comprising water; * the water comprising less than 17 ppm of calcium and magnesium; * further comprising approximately 80%wt to approximately 97.5% wt water; * further comprising approximately 85%wt to approximately 95% wt water; * the composition being a liquid; * the composition being a single-phase liquid; * the composition being substantially free of betaine surfactants * the composition being substantially free of enzymes; * the composition being substantially free of an added electrolyte, such as sodium chloride; * the composition being substantially free of chelant; * the composition being substantially free of chelant, other than citric acid; * the composition being substantially free of anionic surfactant; * the composition being substantially free of alkanolamine, such as monoethanolamine, diethanolamine, triethanolamine, or combinations thereof; * the composition being substantially free of glycol ether; * the composition being substantially free of a peroxide; * the composition being substantially free of hydrogen peroxide; * the composition being substantially free of bisguanide; * the composition being substantially free of added alcohol; * the composition being substantially free of added ethanol; * the composition being substantially free of an unsaturated fatty alcohol.

Also disclosed are methods of increasing disinfection activity of a benzylsubstituted quaternary ammonium compound in a disinfecting composition by adding a polyquaternium polymer to the disinfecting composition, the polymer being selected from 10 the group consisting of PQ6 <100kDa, PQ6 200-300kDa, PQ6 400-500 kDa, PQ16 5VP95QVI, PQ16 50VP-50QVI, PQ37, A1000, C113, and combinations thereof. The disclosed methods may include one or more of the following: the disclosed methods provide reduction of a concentration of the benzylsubstituted quaternary ammonium compound while maintaining the germ kill efficacy of the disinfecting composition; the concentration of the benzyl-substituted quaternary ammonium compound being reduced by 50 % wt or greater.

Terms and Definitions As used herein: the symbol "-S" and terms "approximately" and "about" mean plus or minus 10% of the value stated; the term "a" or "an" means one or more; any and all ranges are inclusive of their endpoints, e.g. a ranging from 1vvt% to 25 10vvt% wt includes 1vvt% and 10wt% and any concentration between 1wt% and 10wt%; all amounts given in % are % by weight (wt%) unless otherwise stated. When an ingredient does not contain close or equal to 100% active material, two percentages may be provided: one for the weight of the raw material and one for the weight of the active. For example, 7.28 % wt of benzalkonium chloride contains approximately 80% benzalkonium chloride in water, alcohol and/or polypropylene glycol, which equates to approximately 5.82% wt of benzalkonium chloride in the formulation. This would be represented as 7.28 % wt (5.82 % wt) of benzalkonium chloride; the term "benzyl group" is C6H5CH2-; the term "comprising" is inclusive or open-ended and does not exclude any additional elements; the term "consisting of excludes any additional elements; and the term "consisting essentially of is in-between, only permitting additional elements that do not materially affect characteristics of the product or process; the phrase "substantially free" means a concentration of less than 0.3 g/L, preferably less than 0.2 g/L, more preferably less than 0.1 g/L, and most preferably less than 0.05 g/L; the terms "germ" and "microbe" or "microbial" means microorganisms which causes disease or undesirable effects, such as malodour, and encompasses both bacteria and viruses; the terms "disinfect" or "disinfection" mean no growth observed during the micro testing; the terms "sanitize" or "sanitizer" mean to reduce the level of bacteria (note, not viruses) on a surface to a level that is considered "safe" but not total kill; the terms "biocide" or "biocidal" mean any product that can kill germs, including bacteria and viruses; biocides are substances approved to kill microorganisms and typically registered with a governing body (i.e., the US Environmental Protection Agency or the European Chemicals Agency (ECHA)); the term "liquid" means a state of matter that conforms to the shape of the container in which it is held at room temperature (18-23°C) and which acquires a defined surface in the presence of gravity; the term "liquid" is readily distinguishable from the terms "solid" and "gas." Liquids are not pastes, which behaves as a solid until a sufficiently large load or stress is applied, even though a paste is also known as a Bingham plastic fluid; the term "alone" means that no other ingredients are present, in other words, the stated ingredient is the only ingredient; the term "ambient temperature" means room temperature, which may vary 30 depending on the season from approximately 18°C to approximately 28°C, but preferably from approximately 20°C to approximately 25°C.

Detailed Description

Disinfecting compositions are disclosed comprise a synergistic combination of a benzyl-substituted quaternary ammonium compound and a specified polymer. The disclosed compositions comprise a low concentration of quat, but are still able to obtain germ kill.

The disclosed compositions comprise a benzyl-substituted quaternary ammonium compound. Benzyl-substituted quaternary ammonium compounds have the formula: C6I-15CH2NR3+X-, wherein each R is independently a C1-C18 hydrocarbon group and X is an alkali metal, saccharinate group, or carbonate group. Preferably the benzyl-substituted quaternary ammonium compound has the formula C6H5CH2N(CH3)2R+X-, wherein R is a C12-C18 or C12-C16 alkyl group and X is Cl.

The polymer is selected from the group consisting of poly(diallyldimethylammonium chloride) (PQ6) having a molecular weight <100kDa (PQ6 <100kDa); PQ6 having a molecular weight ranging from 200kDa to 300 kDa (PQ6 200- 300kDa); PQ6 having a molecular weight ranging from 400 kDa to 500 kDa (PQ6 400500 kDa); copolymers of vinylpyrrolidone (VP) and quaternized vinylimidazole (QVI)(PQ16) having 5%wt VP and 95% wt QVI (PQ16 5VP-95QVI); PQ16 having 50%wt VP and 95% wt QV! (PQ16 50VP-50QVI); Poly(2-dimethylamino)ethyl methacrylate) methyl chloride quaternary salt (PQ37); 1-propanaminium, N,N,N-trimethy1-3-[(1-oxo-2- propenyl)amino] chloride, homopolymer (A1000); 1-dodecanaminium, N,N-dimethyl-N- [3-[(2-methy1-1-oxo-2-propen-1-ybamino]propy1]-, chloride (1:1), polymer with sodium 2-methy1-2-[(1-oxo-2-propen-1-yhamino]-1-propanesulfonate (1:1) and N,N,N-trimethy1-3-[(1-oxo-2-propen-1-y0amino]-L propanaminium chloride (1:1) (C113); and combinations thereof.

The concentration of the benzyl-substituted quaternary ammonium compound is approximately 5% wt to approximately 50% wt less than the concentration of the benzylsubstituted quaternary ammonium compound in a comparative disinfecting composition comprising the benzyl-substituted quaternary ammonium compound alone, preferably approximately 6% wt to approximately 40% wt less, more preferably approximately 7% wt to approximately 30% wt less, even more preferably approximately 8% wt to approximately 20% wt less, and more preferably approximately 9% wt to approximately 15% wt less.

To achieve germ kill with the low level of quat, the disclosed composition comprise a polymer, as defined above.

The combination of benzyl-substituted quaternary ammonium compound and specified polymer may comprise all the ingredients necessary for germ kill. As a result, the disclosed compositions may be substantially free of any other known germ kill actives. In other words, the disclosed compositions do not include any additional quaternary ammonium compounds, such as dialkyl dimethyl ammonium chloride. The benzyl-substituted quaternary ammonium compound is the only quat used in the disclosed compositions. Multiple quaternary ammonium species may help achieve sanitization and/or provide better breadth of germ kill. As a result, most commercial sanitizers include a blend of two or more quaternary ammonium compounds.

Applicant believes that using the benzyl-substituted quaternary ammonium compound as the only quat provides an improved safety profile as compared to products containing two or more quaternary ammonium compounds. In vitro epiderm assays were performed on four different compositions containing: (a) 3.70% wt BKC alone, (b) 5.90% wt BKC alone, (c) 5.90% wt blend of BKC and dodecyl dimethyl ammonium chloride (DDAC), and (d) 3.70% wt blend of BKC and DDAC. The results for (a) and (b) were "non-corrosive." The results for (d) were "borderline." The results for (c) were "Corrosive." Applicant was surprised to discover that less damaging results were achieved from concentrations of BKC that are the same or even higher than the concentrations of a combination of BKC and DDAC.

The disclosed compositions are also substantially free of peroxides, such as hydrogen peroxide or peracids. The disclosed compositions are also substantially free of guanides, such as bisguanide. The disclosed compositions are substantially free of alkali metal hypochlorites. The disclosed compositions are substantially free of isocyanurates. The disclosed compositions are also substantially free of borates, such as boric acid or perborates.

The disclosed compositions may further comprise water, preferably soft water.

Soft water comprises less than 17 ppm of calcium and magnesium. The disclosed compositions may comprise approximately 80%wt to approximately 97.5% wt water. As a result the disclosed compositions may be a liquid, preferably a single phase liquid. The disclosed compositions may further comprise customary ingredients typically included in disinfecting compositions, such as anionic surfactants, non-ionic surfactants, organic acids and their salts, chelants, thickeners, pH adjusters, opacifiers, enzymes, non-aqueous solvents, fragrances, dyes, and the like.

Alternatively, the disclosed compositions may be substantially free of non-ionic surfactants. Specially, the disclosed compositions may be substantially free of betaine surfactants. The disclosed compositions may also be substantially free of unsaturated fatty alcohols.

The disclosed compositions may be substantially free of anionic surfactants, such as alkyl sulfates and alkyl ether sulfates.

The disclosed compositions may be substantially free of enzymes.

The disclosed compositions may be substantially free of alkanolamine, such as monoethanolamine, diethanolamine, triethanolamine, or combinations thereof.

The disclosed compositions may be substantially free of non-aqueous solvents, such as glycol ethers. The disclosed compositions may also be substantially free of added alcohols, such as ethanol. One of ordinary skill in the art will recognize that the benzyl-substituted quaternary ammonium compounds are frequently supplied in an alcohol or glycol solvent. However, more of these solvents are not deliberately added to the disclosed compositions.

The disclosed compositions may be substantially free of an added electrolyte, such as sodium chloride.

The disinfecting composition may be used to disinfect hard or soft surfaces. For example, the disinfecting may be used in all-purpose cleaners or hard surface disinfectants, such as triggers, dilutables, or wipes. Alternatively, the disinfecting composition may be used in laundry products, such as laundry biocides, laundry sanitizer, laundry softeners, laundry conditions, laundry fabric protectors, or any combination thereof. Preferably, the disclosed laundry compositions may serve two or more functions.

For example, the disclosed laundry composition may be a fabric protector and biocide, or a fabric protector and sanitizer, or a softener and biocide, or a softener and sanitizer, or a conditioner and biocide, or a conditioner and sanitizer. Alternatively, the disclosed laundry composition may be a fabric protector and softener and conditioner. Alternatively, the disclosed composition may be a biocide and sanitizer.

Contrary the disclosures in the prior art and as shown in the examples that follow, not all polyquaternium polymers behave in the same manner. Indeed, a large quantity of some polyquaternium polymers would be needed to increase the efficacy of BKC. And BKC is inexpensive. As a result, these polyquaternium polymers may be undesirable to use to increase the germ kill of benzyl-substituted quaternary ammonium compounds, especially if they are toxic to aquatic environment. As a result, the disclosed compositions may be substantially free of a polyquaternium polymer selected from the group consisting of poly(acrylamide-co-diallyldimethylammonium chloride (PQ7), copolymers of vinylpyrrolidone and quaternized vinylimidazole having more vinylpyrrolidone units than quatemized vinylimidazole units (PQ16 70VP-30QVI), 2-pyrrolidinone, 1-ethenyl-polymer with N,N,N-trimethy1-3-[(2-methy1-1-oxo-2-propenyl)amino]-1-propanium chloride (PQ28), and combinations thereof. Based on the chemical structure and to be confirmed by testing, Applicant believes that P033 would perform worse antimicrobially than PQ37 and would also be undesirable for use in the teachings herein.

Methods are disclosed for reducing a concentration of a benzyl-substituted quaternary ammonium compound in a disinfecting composition while maintaining the germ kill efficacy of the disinfecting composition by adding a polymer to the disinfecting composition. In other words, the concentration of a benzyl-substituted quaternary ammonium compound in a disinfecting composition may be reduced as compared to a comparative disinfecting composition comprising the benzyl-substituted quaternary ammonium compound alone by adding a first polyquaternium polymer to the disinfecting composition.

As shown in the example that follows, the concentration of benzyl-substituted 30 quaternary ammonium compounds may be reduced when specific polymers are added to the formulation and still provide equivalent germ kill to compositions containing higher concentrations of the benzyl-substituted quaternary ammonium compounds. Benzylsubstituted quaternary ammonium compounds are known to be toxic to aquatic environments. The ability to reduce the concentration of the benzyl-substituted quaternary ammonium compound is therefore beneficial. Additionally, the formulation does not require a large percentage of these polymers, which helps contain formulations costs. The polymer is selected from the group consisting of poly(diallyldimethylammonium chloride) (PQ6) having a molecular weight <100kDa (PQ6 <100kDa); PQ6 having a molecular weight ranging from 200kDa to 300 kDa (PQ6 200-300kDa); PQ6 having a molecular weight ranging from 400 kDa to 500 kDa (PQ6 400- 500 kDa); copolymers of vinylpyrrolidone (VP) and quaternized vinylimidazole (QVI)(PQ16) having 5%wt VP and 95% wt QVI (PQ16 5VP-95QVI); PQ16 having 50%wt VP and 95% wt QVI (PQ16 50VP-50QVI); Poly(2-dimethylamino)ethyl methacrylate) methyl chloride quaternary salt (PQ37); 1-propanaminium, N,N,N-trimethy1-3-[(1-oxo-2-propenyl)amino] chloride, homopolymer (A1000); 1-dodecanaminium, N,N-dimethyl-N- [3-[(2-methyl-1-oxo-2-propen-1-y0amino]propyl]-, chloride (1:1), polymer with sodium 2-methyl-2-[(1-oxo-2-propen-1-yDamino]-1-propanesulfonate (1:1) and N,N,N-trimethy1-3-[(1-oxo-2-propen-1-y0amino]-L propanaminium chloride (1:1) (C113); and combinations thereof.

Exemplary dilutable all purpose cleansers comprise approximately 0.3% wt to 20 approximately 1.5% wt a benzyl-substituted quaternary ammonium compound and approximately 0.06% to approximately 0.16% a first polyquatemium polymer.

Exemplary dilutable all purpose cleaners comprise: Ingredient % wt Preferable % wt Benzyl-substituted quaternary ammonium compound -0.3 to -1.5 -0.4 to -1 Polymer -0.06 to '-0.5 -0.08 to -0.2 Nonionic surfactant, e.g., Lauryl alcohol ethoxylate with 7E0 -1 to -5 -2 to -4 Chelant, e.g., EDTA or MGDA -0.03 to -0.3 -0.05 to -0.2 Sodium borate -0.05 to -0.15 -0.075 to -0.125 Water -80 to -98 -85 to -95 Optional dye and fragrance 0 to -3 -0.0004 to -2 Exemplary all purpose cleansers cleaners comprise approximately 0.05% wt to approximately 0.5% wt a benzyl-substituted quaternary ammonium compound and approximately 0.01% to approximately 0.1% a first polyquaternium polymer.

Exemplary all purpose cleaners comprise: Ingredient % wt Preferable % wt Benzyl-substituted quaternary ammonium compound -0.05 to -0.2 -0.075 to -0.125 Polymer -0.01 to -0.1 -0.015 to -0.075 Nonionic surfactant, e.g., Lauryl dimethylamine oxide -0.1 to -4 -0.2 to -2.5 Alkanolamine -0.1 to -1 -0.25 to -0.8 Glycol ether -0.5 to -3 -0.6 to -2.25 Water -90 to -98 -92 to -97 Optional alcohol 0 to -0.5 -0.1 to -0.3 Optional chelant, e.g., EDTA or MGDA 0 to -0.3 -0.05 to -0.2 Optional dye and fragrance 0 to -3 -0.0004 to -2 Exemplary laundry compositions comprise approximately 2% wt to approximately 4% wt benzyl-substituted quaternary ammonium compound and approximately 0.08% to approximately 0.15% a first polyquaternium polymer, Exemplary laundry compositions comprise: Ingredient % wt Preferable % wt Benzyl-substituted quaternary ammonium compound -2 to -4 -2.5 to -3.5 Polymer -0.08 to -0.5 -0.1 to -0.12 Nonionic surfactant, e.g., Lauryl alcohol ethoxylate with 7E0 -0.4 to -2 -0.5 to -1 Alkali carbonate and/or bicarbonate -0.3 to -1.5 -0.4 to -1 Water -80 to -98 -85 to -95 Optional dye and fragrance 0 to -3 -0.0004 to -2 Exemplary laundry compositions comprise approximately 1% wt to approximately 2% wt dialkyl dimethyl ammonium chloride, approximately 0.4% wt to approximately 0.75% wt benzyl-substituted quaternary ammonium compound, and approximately 0.08% to approximately 0.15% a first polyquaternium polymer, Exemplary laundry compositions comprise: Ingredient % wt Preferable % wt Benzyl-substituted quaternary ammonium compound -0.4 to -0.75 -0.5 to -0.6 Polymer -0.08 to -0.5 -0.1 to -0.12 Dialkyl dimethyl ammonium chloride -1 to -2 -1.25 to -1.75 Nonionic surfactant, e.g., Lauryl alcohol ethoxylate with 7E0 -0.4 to -2 -0.5 to -1 Alkali carbonate and/or bicarbonate -0.3 to -1.5 -0.4 to -1 Water -80 to -98 -85 to -95 Optional dye and fragrance 0 to -3 -0.0004 to -2 Exemplary laundry compositions comprise approximately 1.25% wt to approximately 3.3% wt of a benzyl-substituted quaternary ammonium compound, approximately 0.25% wt to approximately 4% of a first polyquaternium compound, and three or more pH adjusters, the pH adjusters being selected from the group consisting of citric acid, sodium citrate, an alkali hydroxide, and combinations thereof. For example, the exemplary laundry compositions comprise: Ingredient % wt Preferable % wt Benzyl-substituted quaternary ammonium compound -1.25 to -3.3 -1.5 to --3 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-500V1, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.02 Water -80 to -95 -85 to -92.5 In another example, the exemplary laundry compositions comprise: Ingredient % wt Preferable % wt C12-18 or C12-C16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, 0113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Water -80 to --95 -85 to --92.5 When used during the last rinse cycle of a laundry washing process, Applicant believes that these laundry compositions will obtain a 5 logo reduction in Staphylococcus aureus, Enterococcus hirae, Escherichia colt, and Pseudomonas aeruginosa a 4 logo reduction in Candida albicans. This means the above composition will qualify as a laundry disinfectant composition under European regulations.

The laundry compositions may further comprise a softener, which provides softness effect to the fabric, for example to cotton fibers. The exemplary laundry compositions may comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or C12-C16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Polysaccharide-derived softener -0.005 to -1.5 -0.01 to -0.2 Water -80 to -95 -85 to -92.5 Alternatively, the exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or C12-C16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-950V1, P016 50VP-500V1, P037, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Hydrolyzed protein copolymer softener -0.005 to -3 -0.01 to -1 Water -80 to -95 -85 to -92.5 For aesthetic reasons, the laundry compositions may further comprise thickeners, fragrances, and/or dyes. For example, these exemplary laundry compositions comprise, consist essentially of, or consist of.

Ingredient % wt Preferable % wt C12-18 or C12-16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to --3 Polymer (e.g., PQ6, A1000, PQ16 5VP-950V1, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Cellulose based thickener -0.1 to -2 -0.6 to -1.8 Dye 0 to -0.002 -0.0008 to -0.0018 Fragrance 0 to -4 -0.3 to -2 Water -80 to -95 -85 to -92.5 In another example, the exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or 012-16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-950V1, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Methylhydroxyethylcellulose (e.g., SupracareTM 780) -0.1 to -2 -0.6 to -1.8 Dye 0 to -0.002 -0.0008 to -0.0018 Fragrance 0 to -4 -0.3 to -2 Water -80 to -95 -85 to -92.5 In another example, the exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or 012-16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-950V1, PQ16 50VP-500V1, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to --2 -1 to --1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Hydroxypropylmethylcellulose (e.g., CellosizeTM QP100) -0.1 to -2 -0.6 to -1.8 Dye 0 to -0.002 -0.0008 to -0.0018 Fragrance 0 to -4 -0.3 to -2 Water -80 to -95 -85 to -92.5 Compositions that meet germ kill, softness, and other aesthetic parameters may comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or 012-16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-950V1, PQ16 50VP-500V1, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Hydrolyzed protein copolymer softener (e.g., ColtideTM HSi) -0.05 to -2 -0.1 to --1 Methylhydroxyethylcellulose (e.g., SupracareTM 780) -0.25 to -1 -0.5 to -0.7 Dye 0 to -0.002 -0.0008 to -0.0018 Fragrance 0 to -4 -0.3 to -2 Water -80 to -95 -85 to -92.5 In another example, the exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or C12-16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid --4 to -6 -4.5 to --5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Polysaccharide-derived softener (e.g., EcothixTM) -0.05 to -2 -0.1 to -1 Methylhydroxyethylcellulose (e.g., SupracareTM 780) -0.25 to -1 -0.5 to -0.7 Dye 0 to -0.002 -0.0008 to -0.0018 Fragrance 0 to -4 -0.3 to -2 Water -80 to -95 -85 to -92.5 In yet another example, the exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or C12-16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, P037, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Polysaccharide-derived softener (e.g., EcothixTM) -0.05 to -2 -0.1 to -1 Hydroxypropylmethylcellulose (e.g., CellosizeTM QP100) -0.25 to -1 -0.5 to -0.8 Dye 0 to -0.002 -0.0008 to -0.0018 Fragrance 0 to -4 --0.3 to -2 Water -80 to -95 -85 to --92.5 In yet another example, the exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or 012-16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid --4 to -6 -4.5 to --5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Hydrolyzed protein copolymer softener (e.g.,ColtideTM HSi) -0.05 to -2 -0.1 to -1 Hydroxypropylmethylcellulose (e.g., CellosizeTM QP100) -0.25 to -1 -0.5 to -0.8 Dye 0 to -0.002 -0.0008 to -0.0018 Fragrance 0 to -4 -0.3 to -2 Water -80 to -95 -85 to -92.5 Inclusion of encapsulated fragrances in the laundry compositions helps fabrics remain fresh long after washing. For example, these exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or 012-16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Methylhydroxyethylcellulose (e.g., SupracareTM 780) -0.1 to -2 -0.6 to -1.8 Dye 0 to -0.002 -0.0008 to -0.0018 Encapsulated fragrance, preferably having a polyacrylate or biodegradable shell (i.e., not formaldehyde-releasing shells) -0.05 to -1.5 -0.1 to -1 Non-encapsulated fragrance 0 to -4 -0.3 to -2 Water -80 to -95 -85 to -92.5 In another example, the exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or C12-16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid --4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Polysaccharide-derived softener (e.g., EcothixTM) -0.05 to -2 -0.1 to -1 Methylhydroxyethylcellulose (e.g., SupracareTM 780) -0.25 to -1 -0.5 to -0.7 Encapsulated fragrance, preferably having a polyacrylate or biodegradable shell (i.e., not formaldehyde-releasing shells) -0.05 to -1.5 -0.1 to -1 Dye 0 to -0.002 -0.0008 to -0.0018 Non-encapsulated fragrance 0 to -4 -0.3 to -2 Water -80 to -95 -85 to -92.5 In another example, the exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or C12-16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-950V1, P016 50VP-500V1, P037, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Polysaccharide-derived thickener (e.g., EcothixTM) -0.05 to -2 -0.1 to -1 Hydroxypropylmethylcellulose (e.g., CellosizeTM QP100) -0.25 to -1 -0.5 to -0.8 Encapsulated fragrance, preferably having a polyacrylate or biodegradable shell (i.e., not formaldehyde-releasing shells) -0.05 to -1.5 -0.1 to -1 Dye 0 to -0.002 -0.0008 to -0.0018 Non-encapsulated fragrance 0 to -4 -0.3 to -2 Water -80 to -95 -85 to -92.5 In another example, the exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or 012-16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Hydrolyzed protein copolymer softener (e.g.,ColtideTM HSi) -0.05 to -2 -0.1 to -1 Methylhydroxyethylcellulose (e.g., SupracareTM 780) -0.25 to -1 -0.5 to -0.7 Encapsulated fragrance, preferably having a polyacrylate or biodegradable shell (i.e., not formaldehyde-releasing shells) -0.05 to -1.5 -0.1 to -1 Dye 0 to -0.002 -0.0008 to -0.0018 Non-encapsulated fragrance 0 to -4 -0.3 to -2 Water -80 to -95 -85 to -92.5 In another example, the exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-18 or 012-16 alkyl dimethyl benzyl ammonium chloride -1.25 to -3.3 -1.5 to -3 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, 0113, or combos) -0.25 to -4 -0.25 to -1.5 Citric acid -4 to -6 -4.5 to -5.5 Sodium citrate -0.8 to -2 -1 to -1.5 Sodium Hydroxide -0.005 to -0.03 -0.005 to -0.01 Hydrolyzed protein copolymer softener (e.g., ColtideTM HSi) -0.05 to -2 -0.1 to -1 Hydroxypropylmethylcellulose (e.g., CellosizeTM QP100) -0.25 to -1 -0.5 to -0.8 Encapsulated fragrance, preferably having a polyacrylate or biodegradable shell (i.e., not formaldehyde-releasing shells) -0.05 to -1.5 -0.1 to -1 Dye 0 to -0.002 -0.0008 to -0.0018 Non-encapsulated fragrance 0 to -4 -0.3 to -2 Water -80 to -95 -85 to -92.5 Alternatively, exemplary laundry compositions comprise approximately 2% wt to approximately 6% wt of a benzyl-substituted quaternary ammonium compound, approximately 0.25% wt to approximately 4% wt of the polymer, approximately 0.3% wt to approximately 1.5% wt of an alkylamine oxide, and approximately 0.4% wt to approximately 1% wt of phenoxyethanol.

Exemplary laundry compositions comprise: Ingredient % wt Preferable % wt C12-16 or 012-18 alkyl dimethyl benzyl ammonium chloride -2 to -6 -3.5 to -5.5 Alkylamine oxide --0.3 to -1.5 -0.4 to -1 Phenoxyethanol -0.4 to -1 -0.45 to -0.75 Citric acid -0.5 to -1 -0.6 to -0.9 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Water -80 to -97.5 -85 to -95 When used during the last rinse cycle of a laundry washing process, Applicants believe these laundry compositions obtain a 5 logo reduction as tested according to EN1276 and EN1650 in Staphylococcus aureus, Enterococcus hirae, Escherichia coli, and Pseudomonas aeruginosa and a 4 logic) reduction in Candida albicans. This means the above formulation qualifies as a laundry disinfectant composition under European regulations.

The laundry compositions may further comprise a fabric conditioner, which provides a softness effect to the fabric, for example to cotton fibers. The exemplary laundry compositions may comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-16 or C12-18 alkyl dimethyl benzyl ammonium chloride -2 to -6 -3.5 to -5.5 Alkylamine oxide -0.3 to -1.5 -0.4 to -1 Phenoxyethanol -0.4 to -1 -0.45 to -0.75 Citric acid -0.5 to -1 -0.6 to -0.9 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Esterquat -2 to -5 -3 to -4 Water -80 to -97.5 -85 to -95 For aesthetic reasons, the laundry compositions may further comprise thickeners. The thickeners produce a composition having a viscosity ranging from 100 cPs to 500 cPs as measured using a Brookfield viscometer with LV62 spindle at 50 RPM at ambient temperature. For example, these exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt 012-16 or C12-18 alkyl dimethyl benzyl ammonium chloride -2 to -6 -3.5 to -5.5 Alkylamine oxide -0.3 to -1.5 -0.4 to -1 Phenoxyethanol -0.4 to -1 -0.45 to -0.75 Citric acid -0.5 to -1 -0.6 to -0.9 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Cellulose based thickener -0.1 to -0.5 -0.25 to -0.45 Water -80 to -97.5 -85 to -95 Formulations that provide germ kill, viscosity, and softness may comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-16 or C12-18 alkyl dimethyl benzyl ammonium chloride -2 to -6 -3.5 to -5.5 Alkylamine oxide -0.3 to -1.5 -0.4 to -1 Phenoxyethanol -0.4 to -1 -0.45 to -0.75 Citric acid -0.5 to -1 -0.6 to -0.9 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Cellulose based thickener -0.1 to -0.5 -0.25 to -0.45 Esterquat -2 to -5 -3 to -4 Water -80 to -97.5 -85 to -95 These formulations remain clear, single phase solutions, particularly when the cellulose based thickener is 2-hydroxyethyl ether cellulose and the esterquat is a liquid N,N'-di(alkylcarboxyethyl)-N-hydroxyethyl-N-methylammonium methyl sulfate.

For aesthetic reasons, the laundry compositions may further comprise a suspending agent and an opacifier or encapsulated fragrance. Encapsulated fragrances in the laundry formulations helps fabrics remain fresh long after washing. For example, these exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-16 or C12-18 alkyl dimethyl benzyl ammonium chloride -2 to -6 -3.5 to -5.5 Alkylamine oxide -0.3 to -1.5 -0.4 to -1 Phenoxyethanol -0.4 to -1 -0.45 to -0.75 Citric acid -0.5 to -1 -0.6 to -0.9 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, P016 50VP-50QVI, P037, C113, or combos) -0.25 to -4 -0.25 to -1.5 Cellulose based thickener -0.1 to -0.5 -0.25 to -0.45 Fermentation based suspending agent (e.g., CellulonTM R93) -1 to -4 -1.5 to -2.5 Opacifier and/or encapsulated fragrance, preferably having a polyacrylate or biodegradable shell (i.e., not formaldehyde-releasing shells) -0.05 to -2 -0.07 to -1.5 Water -80 to -97.5 -85 to -95 In another example, the exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-16 or C12-18 alkyl dimethyl benzyl ammonium chloride -2 to -4 -2.5 to -3.5 Alkylamine oxide -0.3 to -1.5 -0.4 to -1 Phenoxyethanol -0.4 to --1 -0.45 to -0.75 Citric acid -0.5 to -1 -0.6 to -0.9 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, C113, or combos) -1 to -3 -1.5 to -2.5 Cellulose based thickener -0.1 to -0.5 -0.25 to -0.45 Opacifier and/or encapsulated fragrance, preferably having a polyacrylate or biodegradable shell (i.e., not formaldehyde-releasing shells) -0.05 to -2 -0.07 to -1.5 Water -80 to -97.5 -85 to -95 In this embodiment, polyquaternium 37 may act as both a germ kill booster and suspending agent for the opacifier and/or encapsulated fragrance.

Dye and additional fragrance may be added to improve the aesthetic appeal of the resulting formulation. For example, these exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt 012-16 or C12-18 alkyl dimethyl benzyl ammonium chloride -2 to -8 -4 to -7 Alkylamine oxide -0.3 to -1.5 -0.4 to -1 Phenoxyethanol -0.4 to -1 -0.45 to -0.75 Propylene glycol -0.25 to -1 -0.3 to -0.75 Citric acid -0.5 to -1 -0.6 to -0.9 Sodium Hydroxide -0.01 to -0.05 -0.02 to -0.04 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-500V1, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Cellulose based thickener -0.1 to -0.5 -0.25 to -0.45 Fermentation based suspending agent (e.g., CellulonTM R93) -1 to -4 -1.5 to -2.5 Opacifier and/or encapsulated fragrance, preferably having a polyacrylate or biodegradable shell (i.e., not formaldehyde-releasing shells) -0.05 to -2 -0.07 to -1.5 Dye 0 to -0.002 -0.0008 to -0.0018 Fragrance 0 to -2 -0.3 to -1.5 Water -80 to -97.5 -85 to -95 In another example, the exemplary laundry compositions comprise, consist essentially of, or consist of: Ingredient % wt Preferable % wt C12-16 or C12-18 alkyl dimethyl benzyl ammonium chloride -2 to -8 -4 to -7 Alkylamine oxide -0.3 to -1.5 --0.4 to -1 Phenoxyethanol -0.4 to -1 --0.45 to --0.75 Propylene glycol -0.25 to -1 -0.3 to -0.75 Citric acid -0.5 to -1 --0.6 to --0.9 Sodium Hydroxide -0.01 to -0.05 -0.02 to --0.04 Polymer (e.g., PQ6, A1000, PQ16 5VP-95QVI, PQ16 50VP-50QVI, PQ37, C113, or combos) -0.25 to -4 -0.25 to -1.5 Cellulose based thickener -0.1 to -0.5 -0.25 to --0.45 Opacifier and/or encapsulated fragrance, preferably having a polyacrylate or biodegradable shell -0.05 to -2 -0.07 to -1.5 (i.e., not formaldehyde-releasing shells) Dye 0 to -0.002 -0.0008 to -0.0018 Fragrance 0 to -2 -0.3 to -1.5 Water -80 to -97.5 -85 to -95 In this embodiment, polyquaternium 37 may act as both a germ kill booster and suspending agent for the opacifier and/or encapsulated fragrance.

Examples

The following examples illustrate exemplary formulations as well as preferred embodiments of the invention. It is to be understood that these examples are provided by way of illustration only and that further useful formulations falling within the scope of the present invention and the claims may be readily produced by one skilled in the art without deviating from the scope and spirit of the invention.

The compositions in the following examples were prepared using the ingredients identified in Table A:

Table A:

Abbr CAS Description

BKC 68391-01- C12-18 alkyldimethylbenzylammonium chloride, e.g., BTCTM 1218 (80% in ethanol and water) sold by Stepan 2080 68424-95- Blend of dioctyldimethylammonium chloride, 3 octyldecyldimethylammonium chloride, & didecyldimethylammonium chloride e.g. BARDAC 2080 (80% pure in ethanol and water) sold by Arxada 1010 7173-51-5 Didecyldimethylammonium chloride e.g. BTC 1010-80 (80% pure in ethanol and water) sold by Stepan PQ6 26062-79- Poly(diallyldimethylammonium chloride) e.g., poly(DADMAC) 3 <100kDa (35% in water) or 200-300k or 400-500k (both 20% in water), all sold by Sigma Aldrich PQ7 26590-05- Poly(acrylamide-co-diallyldimethylammonium chloride), e.g., 6 10% solution sold by Sigma Aldrich PQ16 95144-24- Copolymers of vinylpyrrolidone (VP) and quatemized 4 vinylimidazole (QVI)(5VP-95QVI), e.g., LuviquatTM Excellence (38.42% in water) sold by BASF PQ16 95144-24- Copolymers of VP and QVI (50VP-50QVI), e.g., LuviquatTM 4 FC550 (38% in water) sold by BASF PQ16 95144-24- Copolymers of VP and QV! (70VP-30QVI), e.g., LuviquatTM 4 FC370 (38% in water) sold by BASF A1000 26427-01- 1-propanaminium, N,N,N-trimethy1-3-[(1-oxo-2-propenyl)amino] 0 chloride, homopolymer, e.g., N-Durhance A1000 (15-25% in water) sold by Ashland PQ28 131954- 2-pyrrolidinone, 1-ethenyl-, polymer with N,N,N-trimethy1-3-[(2- 48-8 methyl-1-oxo-2-propenyl)amino]-1-propanaminium chloride, e.g., GafquatTM HS-100 (15-25% in water) sold by Ashland PQ37 26161-33- Poly(2-dimethylamino)ethyl methacrylate) methyl chloride 1 quaternary salt, e.g., MADQUAT (100% powder) sold by Sigma Aldrich C113 26427-33- 1-dodecanaminium, N, N-dimethyl-N43-[(2-methy1-1-oxo-2- 1 propen-1-yl)amino]propyl]-, chloride (1:1), polymer with sodium 2-methyl-2-[(1-oxo-2-propen-1-y0amino]-1-propanesulfonate (1:1) and N,N,N-trimethy1-3-[(1-oxo-2-propen-1-yl)aminc]-L propanaminium chloride (1:1), e.g., ChromohanceTM 113 (15- 25% in water) sold by Ashland LO 1643-20-5 Lauramine oxide, e.g., Ammonyx LO (30% in water) sold by Stepan DO 2605-79-0 Decyl amine oxide, e.g. AmmonyxTM DO (30% in water) sold by Stepan PE 122-99-6 Phenoxyethanol, e.g., Protectol PE NA sold by BASF WE 157905- Liquid N, Ni-di(alkylcarboxyethyl)-N-hydroxyethyl-N- 74-3 methylammonium methyl sulfate, e.g., RewoquatTM WE 45 (75% in ethanol) sold by Evonik PG 57-55-6 Propylene glycol DPNB 5131-66-8 Propylene Glycol n-butyl Ether, e.g., DowanolTM PnB sold by Dow EGHE 112-25-4 Ethylene glycol mono hexyl ether, e.g., Hexyl CellosolveTM sold by Dow DPG 25265-71- Dipropylene Glycol HEC 9004-62-0 2-Hydroxyethyl ether cellulose, e.g., NatrosolTM 250 HHR sold by Ashland (>94% in sodium sulfate) NaOH 1310-73-2 Sodium Hydroxide (50% in water) CA 77-92-9 Citric Acid Anhydrous F Various Various Fragrances D Various Various Fragrances Encap Various Various encapsulated fragrances, preferably having a polyacrylate or biodegradable shell (i.e., not formaldehyde-releasing shells) H2O 7732-18-5 Water OPR2 61789-40- Cocamidopropyl betaine (7.5%) and glycol distearate (30%), 0, 627-83- e.g., MackadetTM OPR2 sold by Solvay 8, & 532-32-1 R93 9004-34-6 Mixture of fermentation derived cellulose and benzoic acid, e.g., 65-85-0 CellulonTM R93 sold by CP Kelco US Inc. Example 1 -BKC PQ Antimicrobial Svnerav Inoculum preparation: Take well-defined and typical colonies of Staphylococcus epidermidis from a recent plate of tryptic soy agar (TSA), dissolve and vortex them in a tube containing 30mL of tryptic soy broth (TSB) and incubate for 17+/-1h at 37°C+/-1°C. Quantify by plate count in TSA (incubated for 48h+/-1h at 37°C+/-1°C). Use the broth culture suspension within seven (7) days after the incubation period. Vortex and take 0.2mL from the broth culture and dilute in appropriate volume of 0.85% NaCI to normalize the strain at 3-5x10"5 CFU/mL Test sample gradient creation: Using a micropipette, add 100pL of TSB in a 96-well microtiter plate format. Dispense 100pL of the test sample (polymer) in column 1 (from row A to row H depending on the number of test samples) and 100pL of the same test sample (polymer) in column 2 in their respective rows within 30 minutes of preparing the solution if it has been previously diluted. (both samples are the same) Using a micropipette take 100pL of the sample from column 2 and dilute it in column 3 performing a 1:1 dilution with the diluent already present in the wells, proceeding with a serial dilution up to column 9. Discard the remaining 100 pL.

Inoculum: Within 30 minutes of preparing the gradient and inoculum bacterial suspension, dispense 20 pL of a solution of BKC in the wells from columns 2 to 9. Dispense 100 pL of inoculum using a micropipette into each well in columns 2 to 10. Columns 1 and 11 are the sample sterility test and negative test control columns, respectively. No growth should be observed in these columns. Column 10 is the positive test control and growth should be observed.

To test the polymers antimicrobial activity alone (without BKC) repeat the steps above, without the addition of the 20 pL solution of BKC.

The inoculum must be between 2.5 -4.5 x 10^5 CFU/mL in each well.

Incubate the microwell plate for 24h+/-1h at 37°C+/-1°C.

The minimum inhibitory concentration (MIC) is determined by visually checking the wells for growth. The MIC is defined as the minimal concentration of polymer in the corresponding well without visible growth after 24 hours of incubation. The tests were performed two times for most of the listed polyquaternium polymers. The MIC of BKC alone ranged from 5-8 ppm or 0.3-0.8 ppm in R&D test conditions. One of ordinary skill in the art will recognize that micro testing is not an exact science and results may vary significantly, especially in R&D test conditions. However, these results demonstrate the consistent synergy or lack of synergy between BKC and the polymers. The results are provided in Table 1:

Table 1:

BKC MIC in ppm alone BKC MIC in ppm with polymer Polymer MIC in ppm with BKC Polymer MIC in ppm alone PQ6 5-8 4 0.8 6.25-40 <100 kDa 0.3-0.8 0.075 2 7.8 PQ6 5-8 4 0.8 6.25-40 200-300 kDa 0.3-0.8 0.075 2 7.8 PQ6 5-8 4 0.8 6.25-40 400-500 kDa 0.3-0.8 0.075 3.9 15.6 PQ7 5-8 4 39 1250 0.3-0.8 0.075 250 >250 PQ16 5-8 4 0.8 8-12.5 5VP-95QVI 0.3-0.8 0.075 3.9 15.6 PQ16 5-8 4 0.8 25-47 50VP-50QVI 0.3-0.8 0.075 15.6 62.5 PQ16 5-8 4 39 1250 70VP-30QVI 0.3-0.8 0.075 >250 >250 A1000 5-8 4 0.8 12-16 0.3-0.8 0.075 3.9 23.4 PQ28 5-8 4 0.8 >2500 0.3-0.8 0.075 >250 >250 C113 5-8 4 0.8 12.5-16 0.3-0.8 0.075 3.9 31.2 PQ37 5-8 4 N/A 31 0.3-0.8 0.075 15.6 31.2 * All ppm show 100% wt concentration of active, not % wt raw material ** N/A = not analyzed As shown in Table 1 above, all 3 kDa of PQ6, PQ16 5VP-95QVI, A1000, and C113 exhibit excellent synergy with BKC, especially PQ6 <100kDa and PQ6 200-300 kDa. The combinations permit the disclosed disinfecting concentrations to significantly reduce the quantity of BKC without adding a large quantity of the polymer to the disinfecting compositions.

PQ16 50VP-50QVI and PQ37 also demonstrate synergy, but require a larger quantity of polymer to do so.

PQ7, PQ16 70VP-30VPI and PQ28 require a large quantity of polymer to increase the efficacy of BKC. And BKC is inexpensive. As a result, these polyquaternium polymers may be undesirable to use to increase the germ kill of benzyl-substituted quaternary ammonium compounds, especially if they are toxic to aquatic environment.

Example 2 -Antimicrobial Activity The antimicrobial efficacy of the formulations in Table 2 was determined using AS-1-M F.22714-16 entitled the Standard Test Method for Evaluation of Laundry Sanitizers and Disinfectants (version 15 April 2.016). A greater than 3-login reduction of all organisms (Klebsiella pneumoniae, Staphylococcus aureus) on both the test fabric swatch & simulated wash water for a contact time of 1 to 60 minutes (determined by product specification) at a testing temperature ranging from 4°C to 60°C+1.0°C (determined by product specification) is required to pass the ASTM E2274-16 for a sanitization product. For a disinfecting product, total kill must be achieved. Additional and optional contact times, temperatures, and test organisms may be used.

Microorganisms were subcultured on Nutrient Agar A (through at least one daily transfer), incubating at 35 ± 2°C. On the day prior to testing, the slant was washed and cells transferred into French square bottles containing 20 mL of solidified Nutrient Agar B. The cells were then incubated between 18 to 24 hours at 35 ± 2°C, agar side down.

Growth was then removed using 3-mL dilution fluid and 5 sterile glass beads to suspend the growth. Cultures were then standardized to yield approximately 108 CFUs per mL of S. aureus and 108 CFUs of K. pneumoniae.

The tests were performed using "clean" experimental conditions, which means no organic soil load was included for this test method. For laundry sanitizers/softeners, the desired experimental conditions are "clean conditions" because the laundry sanitizer/softener is used after a laundry detergent in a laundry washing process, i.e. on clean laundry.

As the test is designed to simulate killing bacteria on fabric, the test fabric also needs to be prepared. 300g of test fabric was boiled for 1 hour in 3L of deionized water containing 1.5g NaCO3 and 1.5g nonionic wetting agent. The fabric was then rinsed in boiling water, then in cold water, until there was no longer the appearance of foam. The fabric was then air dried for 24 hours at room temperature. Once dry, the fabric was cut into 2 inch strips, weighing 15 ± 0.1 grams each. The fabric was then secured onto a stainless steel spindle & wrapped precisely 12 times & then secured (as to represent laundry ballast). Furthermore, 1 by 1.5 inch fabric swatches were cut from the remaining fabric & used as carriers for microorganisms. At least 3 carriers were prepared for each organism tested. On the day of testing, these carriers were inoculated with 0.030 mL of prepared inoculum, taking care to distribute evenly across the 1 by 1.5 inch swatches.

Swatches were dried in a 35 ± 2°C incubator for no longer than 30 minutes, and were used within 1 hour of drying. When ready, they were to be placed between the 6th and 7th folds of the simulated ballast, without any overlap of the swatches.

Experimentally, a 1:315 dilution of test substance was prepared in hard water (400 ppm CaCO3) within 3 hours of testing. Approximately 150 mL of this test substance (simulated rinse water) was used to submerge the fabric carrier & ballast in a sterile exposure chamber that is agitated for the desired contact time. The test was allowed to proceed for 25 minutes and then the simulated rinse water and fabric carriers were separately neutralized. The carriers were then plated, and both plates/tubes are incubated for 48±2 hours at 35±2°C. The results were evaluated for sanitization (in terms of logo reduction) or for disinfection (positive or negative result for growth). The results are provided in Table 2: Table 2: Abbr Cl C2 C3 C4 El E2 E3 E4 E5 2080 0 4.4 6.9 4.12 0 0 0 0 0 (80%) (3.52) (5.52) (3.23) 1010 4.4 0 0 0 0 0 0 0 0 (80%) (3.52) BKC 0 2.9 0 2.75 6.9 6.6 6.67 6.67 6.67 (80%) (2.32) (2.2) (5.52) (5.28) (5.34) (5.34) (5.34) LO 1.50 1.50 1.5 1.5 1.5 1.5 1.5 1.5 1.5 (30%) (0.45) (0.45) (0.45) (0.45) (0.45) (0.45) (0.45) (0.45) (0.45) PE 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 WE 2 (1.5) 4 (3) 4 (3) 4.5 4.5 4.5 4.5 4.5 4.5 (75%) (3.38) (3.38) (3.38) (3.38) (3.38) (3.38) PG 0 0 0 0.5 0.5 0.5 0.5 0.5 0.5 HEC 0.3 0.35 0.35 0.35 0.35 0.35 0.35 0.35 0.35 NaOH 0.045 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 (50%) (0.02) (0.02) (0.02) (0.02) (0.02) (0.02) (0.02) (0.02) (0.02) CA 0.85 3 3 0.85 0.85 0.85 0.85 0.85 0.85 OPR2 0 0 0 0.25 0.25 0.25 0.25 0.25 0.25 PQ37 0 0 0 0 0 0.5 1 1 0 R93 0 0 0 0 0 0 0 0 2 Encap 0 0 0 0 0 0 0 0 0.5 F 0 0 0 0 0 0 0 0.8 0.9 D 0 0 0 0 0 0.001 0.001 0.001 0.001 8 8 8 8 H2O q.s. q.s. q.s. q.s. q.s. q.s. q.s. q.s. q.s.

Swatch 0.42 Total 2.1 4.19 Total Total 3.35 Total 4.32 Result Kill Kill Kill Kill Wash 3.97 Total Total Total Total Total Total Total Total Water Kill Kill Kill Kill Kill Kill Kill Kill Result These results demonstrate that BKC is more efficacious than Dialkyl Dimethyl Ammonium Chlorides (DDAC or 2080 and 1010) alone (at an equivalent level). The results also suggest that BKC alone is performing better (or at least the same as) a blend of BKC and DDAC. Finally, these results demonstrate that the concentration of BKC can be lowered by addition of P037 (E2 and E4) and still obtain germ kill equivalent to that obtained from a higher concentration of BKC (El).

For context, it is typically observed in the ASTM 2274 method that meeting success criteria on the swatch is more challenging than in the wash water. This is likely due to mobility of the active agents and their ability to penetrate deep into the simulated ballast to reach the inoculated fabric carriers. Inversely, the simulated rinse water is similar to a solution, where there is little interference between the active substance and any particles suspended therein.

Example 3 -Micro Efficacy Synergies -PQ6 The antimicrobial efficacy of the formulations in Table 3 was determined using ASTM E2274-16 entitled the Standard Test Method for Eva nation of Laundry Sanitizers and Disinfectants (version 15 Atari: 2016), as described in Example 2.

Table 3:

Formula E6 E7 E8 BKC (80%) 8.125 (6.5) 7.25 (5.8%) 7.8125 (6.25) LO (30%) 1.50 (0.45) 1.50 (0.45) 1.50 (0.45) DO (30%) PE 0.5 0.5 0.5 PG 0.5 0.5 0.5 PQ6 1.0 (0.4) 1.0 (0.4)

DPNB

EGHE

DPG

NaOH (50%) 0.05 (0.02) 0.05 (0.02) 0.05 (0.02) CA 0.85 0.85 0.85 H2O q.s. q.s. q.s.

Swatch Result 2.67 2.38 Total Kill Wash Water Result Total Kill Total Kill Total Kill Table 3 demonstrates that adding PQ6 boosts the micro efficacy of the formula. By adding 0.4% active amount of PQ6 to Formula E7, we were able to reduce the quat by 0.7% and to achieve a similar micro result. Formula E8 also shows a significant improvement in micro efficacy as we reduced the quat by 0.25% and added 0.4% PQ6 compared to Formula E6. Because many quats used for germ kill can add corrosivity or environmental hazards to a product, finding synergies such as PQ6 can lead to better optimized formulations.

The foregoing description of various aspects of the invention has been presented for purposes of illustration and description. Embodiments and/or features therein may be freely combined with one another. It is not intended to be exhaustive or to limit the invention to the precise form disclosed, and obviously, many modifications and variations are possible. Such modifications and variations that may be apparent to a person skilled in the art are intended to be included within the scope of the invention as defined by the accompanying claims.

Claims (21)

1. We claim: 1. A disinfecting composition comprising: at least approximately 0.00001 % wt of a benzyl-substituted quaternary ammonium compound, and a polymer selected from the group consisting of poly(diallyldimethylammonium chloride) (PQ6) having a molecular weight <100kDa (PQ6 <100kDa); PQ6 having a molecular weight ranging from 200kDa to 300 kDa (PQ6 200-300kDa); PQ6 having a molecular weight ranging from 400 kDa to 500 kDa (PQ6 400-500 kDa); copolymers of vinylpyrrolidone (VP) and quaternized vinylimidazole (QVI)(PQ16) having 5%wt VP and 95% wt QVI (PQ16 5VP-95QVI); PQ16 having 50%wt VP and 95% wt QVI (PQ16 50VP-50QVI); Poly(2-dimethylamino)ethyl methacrylate) methyl chloride quaternary salt (PQ37); 1-propanaminium, N,N,N-trimethy1-3-[(1-oxo-2-propenyl)amino] chloride, homopolymer (A1000); 1-dodecanaminium, N,N-dimethyl-N-[3-[(2-methyl-l-oxo-2-propen-l-y0amino]propyl]-, chloride (1:1), polymer with sodium 2-methyl-2-[(1-oxo-2-propen-l-yl)amino]-1-propanesulfonate (1:1) and N,N,N-trimethy1-3-[(1-oxo-2-propen-1-y0amino]-L propanaminium chloride (1:1) (C113); and combinations thereof.
2. 2. The disinfecting composition of claim 1, wherein the disinfecting composition comprises approximately 0.05% wt to approximately 0.2% wt of the benzyl-substituted quaternary ammonium compound and approximately 0.01% wt to approximately 0.1% wt of the polymer and the disinfecting composition is an all-purpose cleaner.
3. 3. The disinfecting composition of claim 1, wherein the disinfecting composition comprises approximately 0.3% wt to approximately 1.5% wt of the benzyl-substituted quatemary ammonium compound and approximately 0.06% wt to approximately 0.5% wt of the polymer and the disinfecting composition is a dilutable all-purpose cleaner.
4. 4. The disinfecting composition of claim 1, wherein the disinfecting composition comprises approximately 2% wt to approximately 4% wt of the benzyl-substituted quaternary ammonium compound and approximately 0.08% wt to approximately 0.5% wt of the polymer and the disinfecting composition is a laundry sanitizer.
5. 5. The disinfecting composition of claim 1, wherein the disinfecting composition comprises approximately 1% wt to approximately 2% wt of a dialkyl dimethyl ammonium chloride, approximately 0.4% wt to approximately 0.75% wt of the benzyl-substituted quaternary ammonium compound, and approximately 0.08% to approximately 0.15% of the polymer and the disinfecting composition is a laundry sanitizer.
6. 6. The disinfecting composition of claim 1, wherein the disinfecting composition comprises approximately 1.25% wt to approximately 3.3% wt of the benzyl-substituted quaternary ammonium compound, approximately 0.25% wt to approximately 4% wt of the polymer, and approximately 4%wt to approximately 6% wt of citric acid, and the disinfecting composition is a laundry sanitizer.
7. 7. The disinfecting composition of claim 1, wherein the disinfecting composition comprises approximately 2% wt to approximately 6% wt of the benzyl-substituted quaternary ammonium compound and approximately 0.25% wt to approximately 4% wt of the polymer and the disinfecting composition is a laundry sanitizer.
8. 8. The disinfecting composition of claim 1, wherein the disinfecting composition comprises a reduced concentration of the benzyl-substituted quaternary ammonium compound as compared to a concentration of the benzyl-substituted quaternary ammonium compound in a first comparative disinfecting composition comprising the benzyl-substituted quaternary ammonium compound alone.
9. 9. The disinfecting composition of claim 8, wherein the concentration of the benzylsubstituted quaternary ammonium compound in the disinfecting composition is reduced by fifty percent or more as compared to the concentration of the benzyl-substituted quaternary ammonium compound in the first comparative disinfecting composition comprising the benzyl-substituted quaternary ammonium compound alone.
10. 10. The disinfecting composition according to any one of claims 1 to 9, wherein the polymer is PQ6 <100kDa, PQ6 200-300 kDa, PQ6 400-500 kDa, PQ16 5VP-95QVI, A1000, C113, or combinations thereof.
11. 11. The disinfecting composition according to any one of claims 1 to 9, wherein the polymer is PQ6 <100kDa, PQ6 200-300 kDa, or combinations thereof.
12. 12. The disinfecting composition according to any one of claims 1 to 9, wherein the 10 polymer is PQ6 <100kDa.
13. 13. The disinfecting composition according to any one of claims 1 to 9, wherein the polymer is PQ6 200-300 kDa.
14. 14. The disinfecting composition according to any one of claims 1 to 9, wherein the polymer is PQ6 400-500 kDa
15. 15. The disinfecting composition according to any one of claims 1 to 9, wherein the polymer is PQ16 5VP-95QVI.
16. 16. The disinfecting composition according to any one of claims 1 to 9, wherein the polymer is PQ16 50VP-50QVI
17. 17. The disinfecting composition according to any one of claims 1 to 9, wherein the 25 polymer is PQ37
18. 18. The disinfecting composition according to any one of claims 1 to 9, wherein the polymer is A1000
19. 19. The disinfecting composition according to any one of claims 1 to 9, wherein the polymer is C113.
20. 20. The disinfecting composition of any one of claims 1 to 19, wherein the disinfecting composition comprises (a) a reduced concentration of the benzyl-substituted quaternary ammonium compound as compared to a concentration of the benzyl-substituted quaternary ammonium compound in a first comparative disinfecting composition comprising the benzyl-substituted quaternary ammonium compound alone and (b) a reduced concentration of the polymer as compared to a concentration of the polymer in a second comparative disinfecting composition comprising the polymer alone.
21. 21. A method of increasing disinfection activity of a benzyl-substituted quaternary ammonium compound in a disinfecting composition by adding a polyquaternium polymer to the disinfecting composition, the polymer being selected from the group consisting of PQ6 <100kDa, PQ6 200-300kDa, PQ6 400-500 kDa, PQ16 5VP-95QVI, PQ16 50VP50QVI, PQ37, A1000, C113, and combinations thereof.