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GB2449156B8 - Semi-synthetic glycopeptides with antibacterial activity. - Google Patents

Semi-synthetic glycopeptides with antibacterial activity.

Info

Publication number
GB2449156B8
GB2449156B8 GB0807351A GB0807351A GB2449156B8 GB 2449156 B8 GB2449156 B8 GB 2449156B8 GB 0807351 A GB0807351 A GB 0807351A GB 0807351 A GB0807351 A GB 0807351A GB 2449156 B8 GB2449156 B8 GB 2449156B8
Authority
GB
United Kingdom
Prior art keywords
semi
antibacterial activity
synthetic glycopeptides
glycopeptides
synthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB0807351A
Other versions
GB2449156A (en
GB2449156B (en
GB0807351D0 (en
Inventor
Daniel Chu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lead Therapeutics Inc
Original Assignee
Lead Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lead Therapeutics Inc filed Critical Lead Therapeutics Inc
Publication of GB0807351D0 publication Critical patent/GB0807351D0/en
Publication of GB2449156A publication Critical patent/GB2449156A/en
Publication of GB2449156B publication Critical patent/GB2449156B/en
Application granted granted Critical
Publication of GB2449156B8 publication Critical patent/GB2449156B8/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
GB0807351A 2007-05-08 2008-04-23 Semi-synthetic glycopeptides with antibacterial activity. Expired - Fee Related GB2449156B8 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91670107P 2007-05-08 2007-05-08

Publications (4)

Publication Number Publication Date
GB0807351D0 GB0807351D0 (en) 2008-05-28
GB2449156A GB2449156A (en) 2008-11-12
GB2449156B GB2449156B (en) 2010-04-28
GB2449156B8 true GB2449156B8 (en) 2010-06-02

Family

ID=39494067

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0807351A Expired - Fee Related GB2449156B8 (en) 2007-05-08 2008-04-23 Semi-synthetic glycopeptides with antibacterial activity.

Country Status (5)

Country Link
AR (1) AR066345A1 (en)
GB (1) GB2449156B8 (en)
HK (1) HK1125114A1 (en)
TW (1) TW200848062A (en)
WO (1) WO2008140973A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100105607A1 (en) * 2008-10-24 2010-04-29 Lead Therapeutics, Inc. Novel semi-synthetic glycopeptides as antibacterial agents
GB2465863A (en) * 2008-12-05 2010-06-09 Lead Therapeutics Inc Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections
WO2011140009A1 (en) * 2010-05-04 2011-11-10 Biomarin Pharmaceutical Inc. Methods of using semi-synthetic glycopeptides as antibacterial agents
CN105585617A (en) * 2016-03-24 2016-05-18 中国医学科学院医药生物技术研究所 Norvancomycin derivatives and preparation purifying method thereof
WO2018102890A1 (en) * 2016-12-09 2018-06-14 The University Of Queensland Visualization constructs
EP3554529A4 (en) * 2016-12-09 2020-06-24 The University of Queensland Glycopeptide antibiotic constructs

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE873523L (en) * 1986-12-30 1988-06-30 Memorex Corp Glycosylated glycopeptides
CA1339808C (en) * 1988-10-19 1998-04-07 Manuel Debono Glycopeptide antibiotics
NZ509165A (en) * 1998-07-14 2003-08-29 Univ Princeton Glycopeptide antobiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
WO2003070756A2 (en) * 2002-02-18 2003-08-28 Combinature Biopharm Ag Novel glycopeptide antibiotics and method for synthesis thereof
WO2004019970A2 (en) * 2002-08-30 2004-03-11 K.U. Leuven Research And Development Glycopeptide antibiotic and semisynthetic derivatives thereof and their use as antiviral agents
WO2006057303A1 (en) * 2004-11-29 2006-06-01 National University Corporation Nagoya University Glycopeptide antibiotic monomer derivatives
US7368422B2 (en) * 2005-02-28 2008-05-06 Novartis Vaccines And Diagnostics Inc. Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity

Also Published As

Publication number Publication date
AR066345A1 (en) 2009-08-12
GB2449156A (en) 2008-11-12
HK1125114A1 (en) 2009-07-31
GB2449156B (en) 2010-04-28
GB0807351D0 (en) 2008-05-28
TW200848062A (en) 2008-12-16
WO2008140973A1 (en) 2008-11-20

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732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)

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PCNP Patent ceased through non-payment of renewal fee

Effective date: 20130423