GB2372502B - Carbohydrate compounds containing cholesterol and their use - Google Patents
Carbohydrate compounds containing cholesterol and their useInfo
- Publication number
- GB2372502B GB2372502B GB0113781A GB0113781A GB2372502B GB 2372502 B GB2372502 B GB 2372502B GB 0113781 A GB0113781 A GB 0113781A GB 0113781 A GB0113781 A GB 0113781A GB 2372502 B GB2372502 B GB 2372502B
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds containing
- containing cholesterol
- carbohydrate compounds
- carbohydrate
- cholesterol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title 2
- -1 Carbohydrate compounds Chemical class 0.000 title 1
- 235000012000 cholesterol Nutrition 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Priority Applications (26)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/008,129 US20020188023A1 (en) | 2000-12-12 | 2001-11-05 | Compound |
DE60117465T DE60117465T2 (en) | 2000-12-12 | 2001-12-05 | LIPIDE WITH AMINOXY GROUP |
CZ20031637A CZ298560B6 (en) | 2000-12-12 | 2001-12-05 | Process for preparing modified lipids |
EP01270543A EP1351972B1 (en) | 2000-12-12 | 2001-12-05 | Lipids comprising an aminoxy group |
DK01270543T DK1351972T3 (en) | 2000-12-12 | 2001-12-05 | Lipids comprising an amine oxy group |
PCT/GB2001/005385 WO2002048170A1 (en) | 2000-12-12 | 2001-12-05 | Lipids comprising an aminoxy group |
JP2002550095A JP2004522722A (en) | 2000-12-12 | 2001-12-05 | Compound |
CNB018225276A CN100482676C (en) | 2000-12-12 | 2001-12-05 | N-oxy-group-contained lipids |
JP2002549701A JP2004520301A (en) | 2000-12-12 | 2001-12-05 | Lipids containing aminoxy groups |
RU2003120456/15A RU2003120456A (en) | 2000-12-12 | 2001-12-05 | COMPOUND |
CNA018226000A CN1524125A (en) | 2000-12-12 | 2001-12-05 | Compound |
CZ20031636A CZ20031636A3 (en) | 2000-12-12 | 2001-12-05 | Compound capable to act as a cationic lipid |
EP06075338A EP1669366A1 (en) | 2000-12-12 | 2001-12-05 | Lipids comprising an aminoxy group |
EP01270614A EP1377673A2 (en) | 2000-12-12 | 2001-12-05 | Glycosilated cationic lipids for liposomes used in drug delivery |
CA002431896A CA2431896A1 (en) | 2000-12-12 | 2001-12-05 | Compound |
AU2212802A AU2212802A (en) | 2000-12-12 | 2001-12-05 | Lipids comprising an aminoxy group |
PCT/GB2001/005383 WO2002048380A2 (en) | 2000-12-12 | 2001-12-05 | Glycosilated cationic lipids for liposomes used in drug delivery |
AT01270543T ATE318834T1 (en) | 2000-12-12 | 2001-12-05 | LIPIDS WITH AMINOOXY GROUP |
RU2003120455/04A RU2290409C2 (en) | 2000-12-12 | 2001-12-05 | Method for preparing compounds, composition for preparing medicinal agent |
ES01270543T ES2259007T3 (en) | 2000-12-12 | 2001-12-05 | LIPIDS THAT INCLUDE AN AMINOXI GROUP. |
CA002364392A CA2364392A1 (en) | 2000-12-12 | 2001-12-05 | Compound |
AU2002222128A AU2002222128B2 (en) | 2000-12-12 | 2001-12-05 | Lipids comprising an aminoxy group |
US10/450,356 US20040081687A1 (en) | 2000-12-12 | 2001-12-05 | Compound |
AU2002220894A AU2002220894A1 (en) | 2000-12-12 | 2001-12-05 | Compound |
CA002364730A CA2364730A1 (en) | 2000-12-12 | 2001-12-06 | Lipids comprising an aminoxy group |
HK03109313A HK1057048A1 (en) | 2000-12-12 | 2003-12-22 | Lipids comprising an aminoxy group |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/GB2000/004767 WO2001048233A1 (en) | 1999-12-23 | 2000-12-12 | Viral core protein-cationic lipid-nucleic acid-delivery complexes |
Publications (3)
Publication Number | Publication Date |
---|---|
GB0113781D0 GB0113781D0 (en) | 2001-07-25 |
GB2372502A GB2372502A (en) | 2002-08-28 |
GB2372502B true GB2372502B (en) | 2004-10-13 |
Family
ID=9886610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB0113781A Expired - Fee Related GB2372502B (en) | 2000-12-12 | 2001-06-06 | Carbohydrate compounds containing cholesterol and their use |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB2372502B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1735626A2 (en) * | 2004-04-16 | 2006-12-27 | EVOTEC Neurosciences GmbH | Diagnostic and therapeutic use of kcnc1 for neurodegenerative diseases |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994004545A1 (en) * | 1992-08-11 | 1994-03-03 | Rijksuniversiteit Leiden | Triantennary cluster glycosides, their preparation and use |
WO1997039019A1 (en) * | 1996-04-12 | 1997-10-23 | University Of Pittsburgh | Novel cationic cholesteryl derivatives containing cyclic polar groups |
-
2001
- 2001-06-06 GB GB0113781A patent/GB2372502B/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994004545A1 (en) * | 1992-08-11 | 1994-03-03 | Rijksuniversiteit Leiden | Triantennary cluster glycosides, their preparation and use |
WO1997039019A1 (en) * | 1996-04-12 | 1997-10-23 | University Of Pittsburgh | Novel cationic cholesteryl derivatives containing cyclic polar groups |
Non-Patent Citations (1)
Title |
---|
WPI Abstract Acc. No. 1994-347142 and JP620071597A * |
Also Published As
Publication number | Publication date |
---|---|
GB2372502A (en) | 2002-08-28 |
GB0113781D0 (en) | 2001-07-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
732E | Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977) | ||
732E | Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977) | ||
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20090606 |