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GB2337703A - Pharmaceutical compositions - Google Patents

Pharmaceutical compositions

Info

Publication number
GB2337703A
GB2337703A GB9921495A GB9921495A GB2337703A GB 2337703 A GB2337703 A GB 2337703A GB 9921495 A GB9921495 A GB 9921495A GB 9921495 A GB9921495 A GB 9921495A GB 2337703 A GB2337703 A GB 2337703A
Authority
GB
United Kingdom
Prior art keywords
fatty acid
mixture
cyclosporin
hydrophilic
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB9921495A
Other versions
GB9921495D0 (en
Inventor
Jong Soo Woo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of GB9921495D0 publication Critical patent/GB9921495D0/en
Publication of GB2337703A publication Critical patent/GB2337703A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to a cyclosporin-containing soft capsule preparation which comprises a composition containing cyclosporin as an active ingredient; a hydrophilic component polyethylene glycol or a non-hydrophilic component propylene carbonate or their mixture, one or a mixture of two or more selected from the group consisting of an esterified compound of fatty acid and primary alcohol, medium chain fatty acid triglyceride and fatty acid monoglyceride as an oil component; and a surfactant having an HLB (Hydrophilic Lipophilic Balance) value of 8 to 17.
GB9921495A 1997-03-14 1998-03-12 Pharmaceutical compositions Withdrawn GB2337703A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019970008750A KR19980073479A (en) 1997-03-14 1997-03-14 Cyclosporine-containing soft capsules
PCT/EP1998/001432 WO1998041225A1 (en) 1997-03-14 1998-03-12 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
GB9921495D0 GB9921495D0 (en) 1999-11-17
GB2337703A true GB2337703A (en) 1999-12-01

Family

ID=19499792

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9921495A Withdrawn GB2337703A (en) 1997-03-14 1998-03-12 Pharmaceutical compositions

Country Status (24)

Country Link
EP (1) EP0969857A1 (en)
JP (1) JP3748573B2 (en)
KR (2) KR19980073479A (en)
CN (1) CN1161150C (en)
AR (1) AR012054A1 (en)
AU (1) AU741923B2 (en)
BR (1) BR9808324A (en)
CA (1) CA2283901A1 (en)
CO (1) CO4940404A1 (en)
CZ (1) CZ324399A3 (en)
DE (1) DE19882184T1 (en)
GB (1) GB2337703A (en)
HU (1) HUP0001515A3 (en)
ID (1) ID23531A (en)
IL (1) IL131703A0 (en)
MY (1) MY118614A (en)
NO (1) NO994436L (en)
PE (1) PE59499A1 (en)
PL (1) PL335729A1 (en)
RU (1) RU2185188C2 (en)
SK (1) SK123299A3 (en)
TR (1) TR199902229T2 (en)
WO (1) WO1998041225A1 (en)
ZA (1) ZA982117B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2380674B (en) * 1998-03-06 2003-05-28 Novartis Ag Emulsion preconcentrates containing cyclosporin or a macrolide
US7203158B2 (en) * 2000-12-06 2007-04-10 Matsushita Electric Industrial Co., Ltd. OFDM signal transmission system, portable terminal, and e-commerce system
GB0526419D0 (en) * 2005-12-23 2006-02-08 Cyclacel Ltd Formulation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0711550A1 (en) * 1994-11-09 1996-05-15 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule compositions
US5589455A (en) * 1994-12-28 1996-12-31 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule compositions
WO1997048410A1 (en) * 1996-06-19 1997-12-24 Novartis Ag Cyclosporin-containing soft capsule preparations
EP0813876A1 (en) * 1996-06-19 1997-12-29 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule preparations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997004810A1 (en) * 1995-07-28 1997-02-13 The Regents Of The University Of California Dax-1 protein, methods for production and use thereof
NZ280689A (en) * 1995-12-15 1997-08-22 Bernard Charles Sherma Sherman Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0711550A1 (en) * 1994-11-09 1996-05-15 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule compositions
US5589455A (en) * 1994-12-28 1996-12-31 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule compositions
WO1997048410A1 (en) * 1996-06-19 1997-12-24 Novartis Ag Cyclosporin-containing soft capsule preparations
EP0813876A1 (en) * 1996-06-19 1997-12-29 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule preparations

Also Published As

Publication number Publication date
MY118614A (en) 2004-12-31
CN1250378A (en) 2000-04-12
DE19882184T1 (en) 2000-02-10
AU6729398A (en) 1998-10-12
SK123299A3 (en) 2000-02-14
EP0969857A1 (en) 2000-01-12
PL335729A1 (en) 2000-05-08
HUP0001515A3 (en) 2000-10-30
CO4940404A1 (en) 2000-07-24
IL131703A0 (en) 2001-03-19
WO1998041225A1 (en) 1998-09-24
JP2000514831A (en) 2000-11-07
PE59499A1 (en) 1999-07-05
GB9921495D0 (en) 1999-11-17
NO994436D0 (en) 1999-09-13
AR012054A1 (en) 2000-09-27
ID23531A (en) 2000-04-27
CA2283901A1 (en) 1998-09-24
AU741923B2 (en) 2001-12-13
ZA982117B (en) 1998-09-14
BR9808324A (en) 2000-05-16
JP3748573B2 (en) 2006-02-22
RU2185188C2 (en) 2002-07-20
CN1161150C (en) 2004-08-11
TR199902229T2 (en) 1999-12-21
HUP0001515A2 (en) 2000-09-28
CZ324399A3 (en) 1999-12-15
KR20000075940A (en) 2000-12-26
NO994436L (en) 1999-09-13
KR19980073479A (en) 1998-11-05

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)