GB2308810A - Composition for combatting dehydration - Google Patents
Composition for combatting dehydration Download PDFInfo
- Publication number
- GB2308810A GB2308810A GB9627003A GB9627003A GB2308810A GB 2308810 A GB2308810 A GB 2308810A GB 9627003 A GB9627003 A GB 9627003A GB 9627003 A GB9627003 A GB 9627003A GB 2308810 A GB2308810 A GB 2308810A
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- composition
- product
- analgesic
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- 239000000203 mixture Substances 0.000 title claims abstract description 89
- 230000018044 dehydration Effects 0.000 title claims abstract description 21
- 238000006297 dehydration reaction Methods 0.000 title claims abstract description 21
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 38
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims abstract description 30
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 30
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 30
- 230000000202 analgesic effect Effects 0.000 claims abstract description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 24
- 235000010323 ascorbic acid Nutrition 0.000 claims abstract description 17
- 239000011668 ascorbic acid Substances 0.000 claims abstract description 17
- 229960005070 ascorbic acid Drugs 0.000 claims abstract description 17
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims abstract description 15
- 239000001103 potassium chloride Substances 0.000 claims abstract description 15
- 235000011164 potassium chloride Nutrition 0.000 claims abstract description 15
- 235000010241 potassium sorbate Nutrition 0.000 claims abstract description 15
- 239000004302 potassium sorbate Substances 0.000 claims abstract description 15
- 229940069338 potassium sorbate Drugs 0.000 claims abstract description 15
- 239000011780 sodium chloride Substances 0.000 claims abstract description 15
- 229930091371 Fructose Natural products 0.000 claims abstract description 14
- 239000005715 Fructose Substances 0.000 claims abstract description 14
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims abstract description 14
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 14
- 229930006000 Sucrose Natural products 0.000 claims abstract description 14
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims abstract description 14
- 239000008103 glucose Substances 0.000 claims abstract description 14
- 239000005720 sucrose Substances 0.000 claims abstract description 14
- 206010019133 Hangover Diseases 0.000 claims abstract description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
- 238000004040 coloring Methods 0.000 claims description 7
- 239000004615 ingredient Substances 0.000 claims description 7
- 208000024891 symptom Diseases 0.000 claims description 6
- 229960004543 anhydrous citric acid Drugs 0.000 claims description 5
- 239000000796 flavoring agent Substances 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 4
- 238000004090 dissolution Methods 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims 3
- 206010012735 Diarrhoea Diseases 0.000 abstract description 2
- 239000000047 product Substances 0.000 description 37
- 238000009472 formulation Methods 0.000 description 7
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 4
- 244000248349 Citrus limon Species 0.000 description 4
- 235000005979 Citrus limon Nutrition 0.000 description 4
- 235000011941 Tilia x europaea Nutrition 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 239000004571 lime Substances 0.000 description 4
- 235000000346 sugar Nutrition 0.000 description 4
- 239000002253 acid Substances 0.000 description 3
- 229960004106 citric acid Drugs 0.000 description 3
- 239000012141 concentrate Substances 0.000 description 3
- 239000003792 electrolyte Substances 0.000 description 3
- 230000035922 thirst Effects 0.000 description 3
- 229930003231 vitamin Natural products 0.000 description 3
- 235000013343 vitamin Nutrition 0.000 description 3
- 239000011782 vitamin Substances 0.000 description 3
- 229940088594 vitamin Drugs 0.000 description 3
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 2
- 241000207199 Citrus Species 0.000 description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 2
- 229930003268 Vitamin C Natural products 0.000 description 2
- 229960001138 acetylsalicylic acid Drugs 0.000 description 2
- 239000004599 antimicrobial Substances 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 235000020971 citrus fruits Nutrition 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000003204 osmotic effect Effects 0.000 description 2
- 150000008163 sugars Chemical class 0.000 description 2
- 235000019154 vitamin C Nutrition 0.000 description 2
- 239000011718 vitamin C Substances 0.000 description 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- 206010008631 Cholera Diseases 0.000 description 1
- 239000004150 EU approved colour Substances 0.000 description 1
- 206010016952 Food poisoning Diseases 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 206010017964 Gastrointestinal infection Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 150000001746 carotenes Chemical class 0.000 description 1
- 235000005473 carotenes Nutrition 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 210000003722 extracellular fluid Anatomy 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 230000010006 flight Effects 0.000 description 1
- 208000030304 gastrointestinal bleeding Diseases 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000002267 hypothalamic effect Effects 0.000 description 1
- 230000033001 locomotion Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 229940006093 opthalmologic coloring agent diagnostic Drugs 0.000 description 1
- 229960005489 paracetamol Drugs 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Mycology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
An analgesic free composition soluble in water to form a product for rehydrating or preventing dehydration of an individual, wherein the composition comprises, (percentage/dry weight): Glucose 10 - 70% Sucrose 1 - 50% Fructose 1 - 60% Sodium Chloride 0.5 - 5% Potassium Chloride 0.1 - 2% Potassium Sorbate 0.1 - 2% Citric Acid (anhydrous) 0.5 - 10% Ascorbic Acid 0.05 - 2% The composition can be used to prevent hangovers or used to treat dehydration arising from physical exertion or diarrhoea.
Description
Product for Combating Dehydration
The present invention relates to a product for combatting dehydration, in particular for rehydrating or preventing dehydration of individuals.
Individuals can become dehydrated for a number of reasons; for instance as a result of alcohol consumption, physical exertion, or disease. Typically this results in an imbalance of water and electrolytes.
Consumption of alcohol can result in individuals becoming dehydrated and suffering from associated headaches and/or nausea.
This is typically termed a hangover. A number of products are known in the art which can be taken to relieve the symptoms of a hangover. Generally such products are in powder or tablet form and are added to water to provide a rehydration product for an individual to drink. These products invariably contain an analgesic, such as paracetamol or aspirin, to provide relief from pain. In this manner these products are only to provide rehydration once an individual is dehydrated, they are not designed to prevent dehydration. Moreover, it may be undesirable to use analgesics in this manner. For instance aspirin can exacerbate some of the problems associated with alcohol consumption, such as gastrointestinal bleeding.
It is an object of the present invention to obviate and/or mitigate the above disadvantages by providing a product suitable for rehydrating or preventing dehydration of an individual and which is analgesic free.
The present invention provides an analgesic free composition soluble in water to form a product for rehydrating or preventing dehydration of an individual, wherein the composition comprises, (percentage/dry wt):
Glucose 10 - 70%
Sucrose 1 - 50%
Fructose 1 - 60%
Sodium Chloride 0.5 - 5%
Potassium Chloride 0.5 - 5%
Potassium Sorbate 0.1 - 2%
Citric Acid (anhydrous) 0.5 - 10%
Ascorbic Acid 0.05 - 2%
The invention also relates to an aqueous product which comprises the dry composition dissolved in water.
It has surprisingly been found that the method of formulating the composition in order to produce an aqueous product is important to its function of combatting dehydration.
The present invention further provides a method of producing an aqueous product from the composition of the present invention comprising: (i) forming a first mixture of the glucose, the sucrose, the
fructose and the anhydrous citric acid, in the percentages
disclosed, wherein the anhydrous citric acid is added as
the last ingredient; (ii) forming a second mixture of the sodium chloride, the
potassium chloride, the potassium sorbate and the ascorbic
acid, in the percentages disclosed, wherein the ascorbic
acid is added as the last ingredient; characterised in that
water is added to the first mixture to dissolution of the
said first mixture prior to addition of the second mixture
to the solution so-produced.
Preferably the first and second mixtures are in dry powder form such as may be formed into sachets, granules, tablets and the like.
Without wishing to be bound by any theory it is thought that separating the two acid components and adding these last to each mixture, prevents undesirable reaction of the acids with the other ingredients.
Any additional ingredients such as flavourings and/or colourings can be subsequently included in the product.
Typically when a person becomes dehydrated, there is an increased osmotic pressure of extracellular fluid, which results in a movement of fluid out of the cells; the osmolality of which is increased. It is thought that the sensation of thirst and the need to replace fluid is produced by the increased osmotic pressure of the fluid within cells. However, thirst is not present when the blood alcohol is high; it appears only when the alcohol has been metabolised. It has been suggested that the hypothalamic thirst centres are put out of action by alcohol, just at the time when it is important to replace fluid and prevent dehydration ("The Textbook on Physiology & Biochemistry" (7th Edition) by George Bell et al).
The present invention finds application, for example, in preventing the onset of symptoms associated with a hangover in an individual. The product may also be taken to prevent dehydration rather than to provide rehydration. In the case of preventing the onset of symptoms associated with hangover the product can be taken immediately after alcohol consumption and before any dehydration occurs.
The present invention therefore provides a product suitable for use in preventing the onset of symptoms associated with a hangover. The present invention further provides a product suitable for use in preventing dehydration particularly after alcohol consumption. The present invention still further provides a product suitable for use in rehydrating.
The product of the present invention may also be taken to provide rehydration to an individual after physical exertion or to an individual who is dehydrated due to an illness resulting in diarrhoea, such as from cholera, gastrointestinal infections and food poisoning. Individuals travelling for long periods of time, such as on long haul aircraft flights can also become dehydrated, particularly due to alcohol consumption and may therefore also benefit from taking the product. Furthermore while the application is directed to individuals, more particularly human individuals, the product may be used in veterinary applications in order to rehydrate animals in need of such rehydration.
The product may also contain a number of additional ingredients such as additional sugars, flavourings, colourings, vitamins, stabilisers, whole fruit powder and the like.
Preferably the product is effervescent typically by carbonation using carbon dioxide.
Without wishing to be bound by the following theory, it is believed that the sugars provide energy and aid with the efficient uptake of electrolytes in the small intestine of an individual. The sodium chloride and potassium chloride are electrolyte replenishers. Potassium sorbate is a preservative.
Citric acid is a pH acid control agent and provides some flavouring. Ascorbic acid (vitamin C) in addition to providing an individual with this important vitamin, also provides an antimicrobial and antioxidant function.
The amount of each component in the composition is independently selected, depending on the particular application the composition is to be used for. The amount of glucose in the composition is between 10 - 70%, preferably 15 - 60% and more preferably 20 - 40%. The amount of sucrose in the composition is between 1 - 50%, preferably 5 - 40% and more preferably 10 35%. The amount of fructose in the composition is between 1 60%, preferably 10 - 55% and more preferably 20 - 50%. the amount of sodium chloride in the composition is between 0.5 - 5%, preferably 0.75% - 3% and more preferably 1 - 2%. The amount of potassium chloride in the composition is between 0.5% - 5%, preferably 0.75% - 3% and more preferably 1 - 2%. The amount of potassium sorbate in the composition is between 0.1 - 2%, preferably 0.15 - 1% and more preferably 0.2 - 0.75%. The amount of citric acid (anhydrous) in the composition is between 0.5 10%, preferably 1 - 7.5% and more preferably 1.5% - 5%. The amount of ascorbic acid in the composition is preferably 0.25 2%, preferably 0.075 - 1% and more preferably 0.1 - 0.5%. The above percentages are all percentage/dry weight of the composition.
The composition is dissolved in water to provide the aqueous product. Preferably the composition is dissolved in the ratio of 1 part composition to 10 parts water, more preferably 1 part composition to 5 parts water.
Typically an individual is to take between 200 - 500 ml of the aqueous product, for instance 300 - 400 ml.
The pH of the aqueous product is generally below pH 8.
Preferably the pH of the aqueous product is between 3 - 7.5, more preferably 3 - 5.5.
A particularly preferred formulation of an analgesic free composition embodying the present invention comprises, (percent/dry weight);
Glucose 25 - 35%
Sucrose 20 - 30%
Fructose 35 - 45%
Sodium Chloride 1 - 2%
Potassium Chloride 1 - 2%
Potassium Sorbate 0.25 - 0.5%
Citric Acid (anhydrous) 1.5 - 4.5%
Ascorbic Acid 0.1 - 0.4%
The above formulation is diluted 1 part composition to 5 parts water by weight to provide an aqueous product suitable for rehydrating or preventing dehydration of an individual following alcohol consumption.
A further preferred formulation of an analgesic free composition embodying the present invention comprises, (percentage/dry weight);
Glucose 55 - 60%
Sucrose 2 - 30%
Fructose 1.5 - 30%
Sodium Chloride 1.5 - 2.5%
Potassium Chloride 1.5 - 2.5%
Potassium Sorbate b.25 - 0.5%
Citric Acid (anhydrous) 1.5 - 2.8%
Ascorbic Acid 0.1 - 0.5%
The above formulation is diluted 1 part composition to 5 parts water (by weight) to provide an aqueous product suitable for rehydrating or preventing dehydration of an individual following physical exertion.
A further preferred formulation of an analgesic free composition embodying the present invention comprises, (percentage/dry weight);
Glucose 55 - 60%
Sucrose 20 - 30%
Fructose 1.5 - 2.5%
Sodium Chloride 1.5 - 2.5%
Potassium Chloride 1.5 - 2.5%
Potassium Sorbate 0.25 - 0.5%
Citric Acid (anhydrous) 1.5 - 2.8%
Ascorbic Acid 0.1 - 0.5%
The above formulation is diluted 1 part composition to 5 parts water (by weight) to provide an aqueous product suitable for rehydrating or preventing dehydration of an individual following long periods of travel.
An example of an orange flavoured rehydration product embodied by the present invention is described below.
Example
132g glucose, 180g fructose and 96g sucrose are mixed together as a dry powder. To this mixture is added and mixed in 12g anhydrous citric acid. This mixture is then added to 800 900ml of water and the solution stirred until the mixture dissolves to form a sugar/citric acid solution.
Separately, 6g sodium chloride, 6g potassium chloride and 1.5g potassium sorbate are mixed together, before addition and mixing in of 1.08g ascorbic acid (vitamin C). This dry mixture is then added to the sugar/citric acid solution and stirred until all the mixture dissolves.
5.72g of Natural Orange Flavouring No 1. NA and 3.10g of
Carotene emulsion 12405 is then added to the solution and the solution made to 1 litre by the addition of water. This provides a concentrate which is diluted with water and carbonated to provide the final product. The concentrate is diluted in a ratio of 1 part concentrate to 5 parts water and carbonated by the addition of CO2. The resulting rehydration product has a pH of 3.
The above product has been found to be particularly efficacious in preventing the symptoms associated with a hangover, when taken immediately after alcohol consumption.
The above example can easily be modified to include, antimicrobials, vitamins, colouring agents and the like. The product could also be formulated using naturally effervescent spring water, thus removing the requirement to carbonate the product.
The above product provides an orange flavoured and appropriately coloured rehydrating drink. Alternative formulations for a citrus rehydrating drink and lemon and lime rehydrating drink contain the same principal components in like amounts, but comprise different flavourings/colourings. For example, the citrus rehydrating drink comprises 2.87g of natural lemon and lime flavouring D1415, 2.87g -of natural orange flavouring No 1. NA and 0.0012g of blue H7250 colouring. The lemon and lime rehydrating drink comprises 5.72g lemon and lime flavouring D1415, 0.0075g quinolene yellow H8573 and 0.0015g blue
H7250 colouring.
While the invention has been described in connection with specific embodiments thereof, it will become apparent to those skilled in the art that various modifications to the product and/or further applications can be envisaged.
Claims (22)
1. An analgesic free composition soluble in water to form a
product for rehydrating or preventing dehydration of an
individual, wherein the composition comprises,
(percentage/dry weight):
Glucose 10 - 70%
Sucrose 1 - 50%
Fructose 1 - 60%
Sodium Chloride 0.5 - 5%
Potassium Chloride 0.1 - 2%
Potassium Sorbate 0.1 - 2%
Citric Acid (anhydrous) 0.5 - 10%
Ascorbic Acid 0.05 - 2%
2. An analgesic free composition according to claim 1 wherein
the amount of glucose in the composition is between 15
60%.
3. An analgesic free composition according to claim 1 wherein
either of claims 1 or 2 wherein the amount of sucrose in
the composition is between 5-40%.
4. An analgesic free composition according to any preceding
claim wherein the amount of fructose in the composition is
between 10-55%.
5. An analgesic free composition according to any preceding
claim wherein the amount of sodium chloride in the
composition is between 0.75-38.
6. An analgesic free composition according to any preceding
claim wherein the amount of potassium chloride in the
composition is between 0.75-3%.
7. An analgesic free composition according to any preceding
claim wherein the amount of potassium sorbate in the
composition is between 0.15-1%.
8. An analgesic free composition according to any preceding
claim wherein the amount of citric acid (anhydrous) in the
composition is between 1-7.5%.
9. An analgesic free composition according to any preceding
claim wherein the amount of ascorbic acid in the
composition is between 0.075-1%.
10. An analgesic free product comprising a composition
according to any preceding claim dissolved in the ratio of
1 part composition to 10 parts water.
11. An analgesic free product comprising a composition
according to any one of claims 1 to 9 dissolved in the
ratio of 1 part composition to 5 parts water.
12. An analgesic free product according to either of claims 10
or 11 wherein the pH of the aqueous product is between pH3
7.5.
13. An analgesic free product according to any one of claims 10
to 12 further comprising flavourings and/or colourings in
an amount of, (percentage/dry weight):
flavourings 0.3 - 3%
colourings 0.001% - 2%
14. An analgesic free product comprising a composition
dissolved in the ratio of 1 part composition to 5 parts
water by weight to provide an aqueous product suitable for
rehydrating or preventing dehydration of an individual
following alcohol consumption, wherein the composition
comprises, (percentage/dry weight):
Glucose 25 - 35%
Sucrose 20 - 30%
Fructose 35 - 45%
Sodium Chloride 1 - 2%
Potassium Chloride 1 - 2%
Potassium sorbate 0.25 - 0.5%
Citric Acid (anhydrous)
1.5 - 0.5%
Ascorbic acid 0.1 - 0.4% 15. An analgesic free product comprising a composition
dissolved in the ration of 1 part composition to 5 parts
water by weight to provide an aqueous product suitable for
rehydrating or preventing rehydration of an individual
following physical excertion, wherein the composition
comprises, (percentage/dry weight):
Glucose 55 - 60%
Sucrose 20 - 30%
Fructose 1.5 - 30%
Sodium chloride 1.5 - 2.5%
Potassium Chloride 1.5 - 2.5%
Potassium sorbate 0.25 - 0.5%
Citric Acid (anhydrous) 1.5 - 2.8%
Ascorbic acid 0.1 - 0.5%
16. An analgesic free product comprising a composition
dissolved in the ratio of 1 part composition to 5 parts
water by weight to provide an aqueous product suitable for
rehydrating or preventing dehydration of an individual
following long periods of travel, wherein the composition
comprises, (percentage/dry weight) following long periods
of travel:
Glucose 55 - 60%
Sucrose 20 - 30%
Fructose 1.5 - 2.5%
Sodium chloride 1.5 - 2.5%
Potassium Chloride 1.5 - 2.5%
Potassium sorbate 0.25 - 0.5%
Citric Acid (anhydrous) 1.5 - 2.8%
Ascorbic acid 0.1 - 0.5%
17. An analgesic product according to any one of claims 10 to
16 wherein the product is made effervescent by carbonation.
18. A method of producing an aqueous product according to any
of claims 10 to 17 comprising
(i) forming a first mixture of the glucose, the
sucrose, the fructose and the anhydrous citric acid, in the
percentages disclosed, wherein the anhydrous citric acid is
added as the last ingredient;
(ii) forming a second mixture of the sodium chloride,
the potassium chloride, the potassium sorbate and the
ascorbic acid, in the percentages disclosed, wherein the
ascorbic acid is added as the last ingredient;
characterised in that water is added to the first mixture
to dissolution of the said first mixture prior to addition
of the second mixture to the solution so-produced.
19. A method according to claim 18 wherein the first and second
mixture are in dry powder form.
20. Use of a composition according to any one of claims 1 to 9
in the manufacture of an aqueous product for preventing
dehydration in an individual.
21. Use of a composition according to any one of claims 1 to 9
in the manufacture of an aqueous product for providing
rehydration in an individual.
22. Use of a composition according to either of claims 20 or 21
in the manufacture of an aqueous product for preventing the
onset of symptoms associated with a hangover.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9526741.5A GB9526741D0 (en) | 1995-12-30 | 1995-12-30 | Product for combatting dehydration |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB9627003D0 GB9627003D0 (en) | 1997-02-12 |
| GB2308810A true GB2308810A (en) | 1997-07-09 |
| GB2308810B GB2308810B (en) | 1999-03-24 |
Family
ID=10786218
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB9526741.5A Pending GB9526741D0 (en) | 1995-12-30 | 1995-12-30 | Product for combatting dehydration |
| GB9627003A Expired - Fee Related GB2308810B (en) | 1995-12-30 | 1996-12-27 | Rehydration product |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB9526741.5A Pending GB9526741D0 (en) | 1995-12-30 | 1995-12-30 | Product for combatting dehydration |
Country Status (1)
| Country | Link |
|---|---|
| GB (2) | GB9526741D0 (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU754537B2 (en) * | 1998-05-15 | 2002-11-21 | Chaoying Zhao | Novel pharmaceutical composition for use in emergency treatment and preparation method thereof |
| WO2003006073A1 (en) * | 2001-07-10 | 2003-01-23 | Penam Investments Pty Ltd | A composition and uses therefor for combating hangover |
| WO2003026679A2 (en) * | 2001-09-26 | 2003-04-03 | Pharma Sol International Limited | Saline solutions for clinical or cosmetic use |
| JP2005041853A (en) * | 2003-07-25 | 2005-02-17 | T Langeland Bjorn | Composition stimulating specific metalloenzyme |
| WO2005077464A1 (en) * | 2004-02-17 | 2005-08-25 | Matuschka-Greinffenclau Markus | Alcohol metabolism moderating composition |
| WO2007017139A1 (en) * | 2005-07-29 | 2007-02-15 | Tima Foundation | Composition for moderating alcohol metabolism and for reducing the risk of alcohol induced diseases |
| EP1278557B1 (en) * | 2000-05-04 | 2007-12-19 | Kimberly-Clark Worldwide, Inc. | Ion-sensitive, water dispersible polymers |
| US7563386B2 (en) | 1999-07-26 | 2009-07-21 | Archer-Daniels-Midland Company | De-icing composition and method |
| EP2223617A1 (en) * | 2008-11-20 | 2010-09-01 | Platinum Prestige, S.L. | Method for producing a substance for reducing alcohol levels in the blood, and substance produce |
| WO2021069615A1 (en) | 2019-10-10 | 2021-04-15 | Zobrius Pharma As | Improved anti-hangover composition, its preparation and uses |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1262235A (en) * | 1970-09-03 | 1972-02-02 | Gerard Balakian | Compositions and beverages formed therefrom for replenishing body fluids and minerals lost through perspiration |
| WO1991012734A1 (en) * | 1990-02-27 | 1991-09-05 | University Of Texas System Board Of Regents | Beverage compositions for human consumption |
-
1995
- 1995-12-30 GB GBGB9526741.5A patent/GB9526741D0/en active Pending
-
1996
- 1996-12-27 GB GB9627003A patent/GB2308810B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1262235A (en) * | 1970-09-03 | 1972-02-02 | Gerard Balakian | Compositions and beverages formed therefrom for replenishing body fluids and minerals lost through perspiration |
| WO1991012734A1 (en) * | 1990-02-27 | 1991-09-05 | University Of Texas System Board Of Regents | Beverage compositions for human consumption |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU754537B2 (en) * | 1998-05-15 | 2002-11-21 | Chaoying Zhao | Novel pharmaceutical composition for use in emergency treatment and preparation method thereof |
| US7563386B2 (en) | 1999-07-26 | 2009-07-21 | Archer-Daniels-Midland Company | De-icing composition and method |
| EP1278557B1 (en) * | 2000-05-04 | 2007-12-19 | Kimberly-Clark Worldwide, Inc. | Ion-sensitive, water dispersible polymers |
| US7449448B2 (en) | 2001-07-10 | 2008-11-11 | Penam Investments Pty. Ltd. | Composition and uses therefor for combating hangovers |
| WO2003006073A1 (en) * | 2001-07-10 | 2003-01-23 | Penam Investments Pty Ltd | A composition and uses therefor for combating hangover |
| WO2003026679A2 (en) * | 2001-09-26 | 2003-04-03 | Pharma Sol International Limited | Saline solutions for clinical or cosmetic use |
| WO2003026679A3 (en) * | 2001-09-26 | 2003-10-30 | Pharma Sol Int Ltd | Saline solutions for clinical or cosmetic use |
| US8236863B2 (en) | 2001-09-26 | 2012-08-07 | Pharma Sol International Limited | Saline solutions for clinical or cosmetic use |
| JP2005041853A (en) * | 2003-07-25 | 2005-02-17 | T Langeland Bjorn | Composition stimulating specific metalloenzyme |
| EA011721B1 (en) * | 2004-02-17 | 2009-04-28 | Маркус Граф В. Матушка-Грейффенклау | Composition for moderation of alcohol degradation process within the human body |
| WO2005077464A1 (en) * | 2004-02-17 | 2005-08-25 | Matuschka-Greinffenclau Markus | Alcohol metabolism moderating composition |
| WO2007017139A1 (en) * | 2005-07-29 | 2007-02-15 | Tima Foundation | Composition for moderating alcohol metabolism and for reducing the risk of alcohol induced diseases |
| EA012753B1 (en) * | 2005-07-29 | 2009-12-30 | Тима Фаундейшн | Composition for moderating alcohol metabolism and for reducing the risk of alcohol induced diseases |
| US8580750B2 (en) | 2005-07-29 | 2013-11-12 | Tima Foundation | Composition for moderating alcohol metabolism and for reducing the risk of alcohol induced diseases |
| US9402849B2 (en) | 2005-07-29 | 2016-08-02 | Tima Foundation | Composition for moderating alcohol metabolism and for reducing the risk of alcohol induced diseases |
| EP2223617A1 (en) * | 2008-11-20 | 2010-09-01 | Platinum Prestige, S.L. | Method for producing a substance for reducing alcohol levels in the blood, and substance produce |
| EP2223617A4 (en) * | 2008-11-20 | 2011-04-27 | Nicolas Jose Antonio Belda | Method for producing a substance for reducing alcohol levels in the blood, and substance produce |
| WO2021069615A1 (en) | 2019-10-10 | 2021-04-15 | Zobrius Pharma As | Improved anti-hangover composition, its preparation and uses |
Also Published As
| Publication number | Publication date |
|---|---|
| GB9526741D0 (en) | 1996-02-28 |
| GB2308810B (en) | 1999-03-24 |
| GB9627003D0 (en) | 1997-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20071227 |