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GB2291593B - A pharmacuetical composition for lowering the blood pressure and a process for the preparation thereof - Google Patents

A pharmacuetical composition for lowering the blood pressure and a process for the preparation thereof

Info

Publication number
GB2291593B
GB2291593B GB9515205A GB9515205A GB2291593B GB 2291593 B GB2291593 B GB 2291593B GB 9515205 A GB9515205 A GB 9515205A GB 9515205 A GB9515205 A GB 9515205A GB 2291593 B GB2291593 B GB 2291593B
Authority
GB
United Kingdom
Prior art keywords
lowering
preparation
blood pressure
pharmacuetical composition
pharmacuetical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9515205A
Other versions
GB9515205D0 (en
GB2291593A (en
Inventor
Margit Nagy
Csaba Farsang
Lodia Fedina
Katalin Szemeredi
Gabor Szenasi
Janos Egri
Antal Mosonyi
Borbala Baria
Gizella Toth
Ibolya Nyaradi
Frigyes Goergenyi
Zsuzsa Orr
Geza Floris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of GB9515205D0 publication Critical patent/GB9515205D0/en
Publication of GB2291593A publication Critical patent/GB2291593A/en
Application granted granted Critical
Publication of GB2291593B publication Critical patent/GB2291593B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB9515205A 1994-07-26 1995-07-25 A pharmacuetical composition for lowering the blood pressure and a process for the preparation thereof Expired - Fee Related GB2291593B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9402193A HU214582B (en) 1994-07-26 1994-07-26 Spayable antihypertensive composition and process for it`s production

Publications (3)

Publication Number Publication Date
GB9515205D0 GB9515205D0 (en) 1995-09-20
GB2291593A GB2291593A (en) 1996-01-31
GB2291593B true GB2291593B (en) 1998-03-11

Family

ID=10985460

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9515205A Expired - Fee Related GB2291593B (en) 1994-07-26 1995-07-25 A pharmacuetical composition for lowering the blood pressure and a process for the preparation thereof

Country Status (18)

Country Link
JP (1) JPH08169829A (en)
AT (1) AT402690B (en)
AU (1) AU699386B2 (en)
BE (1) BE1011413A4 (en)
CZ (1) CZ286399B6 (en)
DE (1) DE19527140A1 (en)
EE (1) EE9500029A (en)
FR (1) FR2722988B1 (en)
GB (1) GB2291593B (en)
HR (1) HRP950374A2 (en)
HU (1) HU214582B (en)
IT (1) IT1277348B1 (en)
LT (1) LT4042B (en)
LV (1) LV11026B (en)
PL (1) PL181069B1 (en)
SK (1) SK280463B6 (en)
UA (1) UA39880C2 (en)
YU (1) YU50795A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8236285B2 (en) 1997-10-01 2012-08-07 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001517689A (en) * 1997-10-01 2001-10-09 フレミントン ファーマシューティカル コーポレイション Polar or non-polar buccal spray or capsule
US20030095925A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders
CA2597956C (en) 2005-02-17 2013-07-09 Velcera Pharmaceuticals Transmucosal administration of drug compositions for treating and preventing disorders in animals
DE102006027794A1 (en) * 2006-06-16 2007-12-20 Lts Lohmann Therapie-Systeme Ag Antihypertensive combination wafer
FR2906140B1 (en) * 2006-09-22 2008-12-05 Philippe Perovitch GALENIC FORM FOR TRANSMUCOSUS ADMINISTRATION OF ACTIVE INGREDIENTS

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863970A (en) * 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
US5298258A (en) * 1989-12-28 1994-03-29 Nitto Denko Corporation Acrylic oily gel bioadhesive material and acrylic oily gel preparation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3307422A1 (en) * 1983-03-03 1984-09-06 Bayer Ag, 5090 Leverkusen LIQUID PREPARATIONS OF DIHYDROPYRIDINES, A METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN THE FIGHT AGAINST DISEASES
EP0175671A1 (en) * 1984-08-23 1986-03-26 Kuhlemann & Co. Pharmaceutical preparation and method for the administration of this pharmaceutical preparation
DE3544692A1 (en) * 1985-12-18 1987-06-19 Bayer Ag DIHYDROPYRIDINE SPRAY, METHOD FOR THE PRODUCTION THEREOF AND ITS PHARMACEUTICAL USE
DE3775960D1 (en) * 1986-03-10 1992-02-27 Burghart Kurt PHARMACEUTICAL PREPARATION AND METHOD FOR THE PRODUCTION THEREOF.
DE3779999T2 (en) * 1986-11-14 1992-12-10 Theratech Inc INCREASE IN PENETRATION CAPABILITY BY MEANS OF A SUBSTANCE AND SHORT-CHAIN ALCOHOLIC SYSTEM CONTAINING CHANGES IN THE CELL HELL.
JPS63170316A (en) * 1986-12-30 1988-07-14 Fujimoto Seiyaku Kk Percutaneously absorbable pharmaceutical of nifedipine for external use
DE3714402A1 (en) * 1987-04-30 1988-11-10 Kali Chemie Pharma Gmbh DRUG FORMULATION
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
AT391269B (en) * 1988-12-30 1990-09-10 Burghart Kurt PHARMACEUTICAL PREPARATION
HU205249B (en) * 1990-11-09 1992-04-28 Egyt Gyogyszervegyeszeti Gyar Process for producing suspensive aerosole composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863970A (en) * 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
US5298258A (en) * 1989-12-28 1994-03-29 Nitto Denko Corporation Acrylic oily gel bioadhesive material and acrylic oily gel preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8236285B2 (en) 1997-10-01 2012-08-07 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem

Also Published As

Publication number Publication date
CZ181195A3 (en) 1996-02-14
HU9402193D0 (en) 1994-09-28
JPH08169829A (en) 1996-07-02
LT95084A (en) 1996-06-25
HUT75457A (en) 1997-05-28
PL181069B1 (en) 2001-05-31
LT4042B (en) 1996-09-25
ATA121495A (en) 1996-12-15
EE9500029A (en) 1996-02-15
AU2326995A (en) 1996-02-08
UA39880C2 (en) 2001-07-16
DE19527140A1 (en) 1996-02-01
LV11026B (en) 1996-04-20
AU699386B2 (en) 1998-12-03
FR2722988A1 (en) 1996-02-02
YU50795A (en) 1998-05-15
GB9515205D0 (en) 1995-09-20
IT1277348B1 (en) 1997-11-10
HU214582B (en) 1998-04-28
AT402690B (en) 1997-07-25
GB2291593A (en) 1996-01-31
CZ286399B6 (en) 2000-04-12
ITMI951621A1 (en) 1997-01-26
FR2722988B1 (en) 1999-10-08
SK92295A3 (en) 1996-05-08
SK280463B6 (en) 2000-02-14
HRP950374A2 (en) 1997-10-31
BE1011413A4 (en) 1999-09-07
ITMI951621A0 (en) 1995-07-26
LV11026A (en) 1996-02-20
PL309757A1 (en) 1996-02-05

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20020725