GB2238476A

GB2238476A - Therapeutic aquatic animal and garlic products

Info

Publication number: GB2238476A
Application number: GB8924968A
Authority: GB
Inventors: K T Lalvani
Original assignee: Individual
Current assignee: Individual
Priority date: 1989-11-04
Filing date: 1989-11-04
Publication date: 1991-06-05
Also published as: GB8924968D0

Abstract

Products comprised from oils and/or derivatives and/or preparations derived from fish and/or other aquatic animals and oils and/or extracts and/or powders derived from mature or immature garlic including or excluding the garlic active principle Allicin are useful in lowering cholesterol and saturated fat levels in blood.

Description

COMPOSITIONS OF SOME THERAPEUTIC ADVANTAGE FROM FISH AND OTHER AQUATIC ANIMALS COMBINED WITH GARLIC INCLUDING OR EXCLUDING THE GARLIC ACTIVE PRINCIPLE ALLICIN This invention relates to a novel composition of therapeutic significance prepared from oils and/or derivatives and/or preparations derived from fish and/or other aquatic animals and oils and/or extracts and/or powders derived from mature or immature garlic including or excluding the garlic active principle Allicin.

Garlic has been used for thousands of years both as a culinary flavouring and as a preventative medicine. It appears to have a unique cardiovascular prophylactic effect.

It can significantly reduce blood fats and cholesterol, and seems to have an antithrombotic effect similar to that of aspirin.

The therapeutic value of oils derived from fish and other aquatic animals has only recently been appreciated. The are rich in long chain polyunsaturated fatty acids of the Omega3 series. The two most important Omega-3 acids are Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA).

These have been shown to have a hypotriglyceridaemic action and to a lesser extent a hypocholesterolaemic effect. When these fatty acids are present in the cell membranes and are metabolised to other compounds, the net results include antithrombotic and anti-inflammatory effects. Beneficial effects of these polyunsaturated fatty acids has also been noted in arthritis, cancer, diabetes, heart related diseases including high blood pressure and coronary heart disease, kidney related disorders and psoriasis.

Previously, garlic and aquatic animal preparations have always been presented seperately. Although these previously know individual compositions have given some therapeutic satisfaction, products combining the two would compliment each other and offer increased therapeutic advantage with improved patient compliance and convenience of a two-in-one therapy in a single dose.

It is therefore the principle object of this invention to provide products having therapeutic significance prepared from oils and/or derivatives and/or preparations derived from fish and/or other aquatic animals and oils and/or extracts and/or powders derived from mature or immature garlic including or excluding the garlic active principle Allicin. These products will be presented in hard or soft gelatin capsules and as a liquid for oral administration.

These combination products providing a convenient two-in-one dosage form would have combined desired therapeutic properties which would be more effective than the presently available seperately existing compositions.

Accordingly, the above object has been achieved by providing the two therapies in combinationtcomprising oils and/or derivatives and/or preparations derived from fish and/or other aquatic animals with oils and/or extracts and/r powders derived from mature or immature garlic including or excluding the garlic active principle Allicin. The mixture is encapsulated in hard or soft gelatin capsules or in a liquidoral form with or without any additives, oils or derivatives from plant and animal sources e.g. Beta-sitosterol, a naturally occuring substance found in wheat germ knows for its anticholesterol properties.

It is believed that these combination preparations of oils and/or derivatives and/or preparations derived from fish and/or other aquatic animals with oils and/or extracts and/or powders derived from mature or immature garlic including or excluding active principle Allicin has an added therapeutic advantage over previously known seperately existing compositions.

The following examples illustrate the invention and the advantages thereof. These examples are given by way of illustration only, and are not to be construed as limiting the invention either in scope or in spirit, as many modifications will be apparent from this disclosure to those skilled in the art.

Example i:- Garlic Oil & Cod Liver Oil in Hard or Soft Gelatin Capsules COMPONENT AMOUNT PER CAPSULE Garlic Oil 0.2 mg Cod Liver Oil or Fish Oil 999.8 mg The mixture is blended and then encapsulated in hard or soft gelatin capsules.

Example 2:- Garlic Oil & Cod Liver Oil in Hard or Soft Gelatin Capsules COMPONENT AMOUNT PER CAPSULE Garlic Oil i.O mg Cod Liver Oil or Fish Oil 99.0 mg The mixture is blended and then encapsulated in hard or soft gelatin capsules.

Example 3:- Salmon Oil and Garlic Oil COMPONENT AMOUNT PER TEASPOON (5 gm) Salmon Oil 4.995 gm Garlic Oil 0.005 gm The mixture is blended with or without malt extract and then bottled.

Example 4:- Marine Animal Oil and Garlic Powder in Hard or Soft P Gelatin Capsules COMPONENT AMOUNT PER CAPSULE Marine Animal Oil 0.75 gm Garlic Powder 0.25 gm The mixture is blended and then encapsulated in hard or soft gelatin capsules.

Example 5:- Marine Oil, Garlic Oil & Beta-sitosterol COMPONENT AMOUSTT PER CAPSULE Marine Oil 500 mg Garlic Oil 0.2 mg Beta-sitosterol 100 mg The mixture is blended and then bottled.

Products comprised from oils and/or derivatives and/or preparations derived from fish and /or other aquatic animals and oils and/or extracts and/or powders derived from mature or immature garlic including or excluding the garlic active principle Allicin combined as disclosed herein will have physiological properties of therapeutic importance with respect to the treatment and/or prophylaxis of arthris, cancer, diabetes, heart related diseases including high blood pressure and coranory heart disease, kidney related disorders and psoriasis. Garlic and aquatic animal oil have a dual antithrombotic and anti-inflammatory effect. They lower blood cholesterol and fat levels which is physiologically important.

Claims

i. Compositions of therapeutic significance comprising of oils and/or derivatives and/or preparations derived from fish and/or other aquatic animals with oils and/or extracts and/or powders derived from mature or immature garlic including or excluding the garlic active principle Allicin.
2. Compositions as in Claim 1 in which Beta-sitosterol (a derivative from wheat embryo) may or may not be used.
3. Compositions as in Claim 1 wherein one or more plant based additives and their derivatives or oils may or may not be incorporated.
4. Compositions as in Claims 1,2 & 3 wherein the mixture is encapsulated in hard or soft gelatin capsules.
5. Compositions as in Claims 1,2 & 3 wherein the mixture is bottled as an oral liquid supplement with or without additives such as malt.
6. Compositions as in Claims 2,3 & 4 whereby the product may be used as a therapeutic food for the treatment and/or prophylaxis of arthritis, cancer, diabetes, heart related diseases-including high blood pressure and coronary heart disease, kidney related disorders and psoriasis.
7. Compositions as in Claims 2,3,4 & 5 whereby the product may be used as an antithrombotic and/or anti-inflammatory.
8. Compositions as in Claims 2,3,4 & 5 in which the product may be used to lower blood cholesterol and saturated fat levels.