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GB2200358B - Materials for in vivo detection of cardiac damage, and methods for their preparation - Google Patents

Materials for in vivo detection of cardiac damage, and methods for their preparation

Info

Publication number
GB2200358B
GB2200358B GB8701691A GB8701691A GB2200358B GB 2200358 B GB2200358 B GB 2200358B GB 8701691 A GB8701691 A GB 8701691A GB 8701691 A GB8701691 A GB 8701691A GB 2200358 B GB2200358 B GB 2200358B
Authority
GB
United Kingdom
Prior art keywords
preparation
materials
methods
vivo detection
cardiac damage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8701691A
Other versions
GB8701691D0 (en
GB2200358A (en
Inventor
Peter Cummins
Bernadette Cummins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Birmingham
Original Assignee
University of Birmingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Birmingham filed Critical University of Birmingham
Priority to GB8701691A priority Critical patent/GB2200358B/en
Publication of GB8701691D0 publication Critical patent/GB8701691D0/en
Publication of GB2200358A publication Critical patent/GB2200358A/en
Application granted granted Critical
Publication of GB2200358B publication Critical patent/GB2200358B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1018—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Optics & Photonics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
GB8701691A 1987-01-27 1987-01-27 Materials for in vivo detection of cardiac damage, and methods for their preparation Expired - Lifetime GB2200358B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB8701691A GB2200358B (en) 1987-01-27 1987-01-27 Materials for in vivo detection of cardiac damage, and methods for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8701691A GB2200358B (en) 1987-01-27 1987-01-27 Materials for in vivo detection of cardiac damage, and methods for their preparation

Publications (3)

Publication Number Publication Date
GB8701691D0 GB8701691D0 (en) 1987-03-04
GB2200358A GB2200358A (en) 1988-08-03
GB2200358B true GB2200358B (en) 1991-02-27

Family

ID=10611246

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8701691A Expired - Lifetime GB2200358B (en) 1987-01-27 1987-01-27 Materials for in vivo detection of cardiac damage, and methods for their preparation

Country Status (1)

Country Link
GB (1) GB2200358B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4243648A1 (en) * 1992-12-23 1994-07-07 Boehringer Mannheim Gmbh Method for the determination of myocardial necrosis by means of antibodies against the N-terminal troponin I peptide
CA2162121A1 (en) * 1993-05-17 1994-11-24 Richard W. Wicks Assay for cardiac troponin i
CA2130280C (en) * 1993-08-24 1999-08-31 Lilian Lee Method for purification of cardiac troponin i
WO1996010076A1 (en) * 1994-09-28 1996-04-04 Spectral Diagnostics Inc. A monoclonal antibody to human cardiac troponin i
US6248869B1 (en) 1997-05-29 2001-06-19 Medical Analysis Systems, Inc. Troponin I forms and use of the same
EP2532748B1 (en) * 2011-06-07 2014-10-08 Postech Academy-industry Foundation DNA aptamer specifically binding to human cardiac troponin I
CN106198997B (en) * 2016-06-28 2017-07-28 广州华弘生物科技有限公司 A kind of kit of Quantitative detection troponin and creatine kinase isozyme

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0131834A2 (en) * 1983-07-06 1985-01-23 Yamasa Shoyu Kabushiki Kaisha Monoclonal antibody having specificity to only one type of an isozyme of human cardiac myosin heavy chain

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0131834A2 (en) * 1983-07-06 1985-01-23 Yamasa Shoyu Kabushiki Kaisha Monoclonal antibody having specificity to only one type of an isozyme of human cardiac myosin heavy chain

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Experimental Cell Research (1978)Vol 117 No.2 pp357-370 *
Febs Letters (1974)Vol 40 pages 253-257 *

Also Published As

Publication number Publication date
GB8701691D0 (en) 1987-03-04
GB2200358A (en) 1988-08-03

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19960127