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GB2160544B - Monoclonal antibody to hli and its use for purifying hli - Google Patents

Monoclonal antibody to hli and its use for purifying hli

Info

Publication number
GB2160544B
GB2160544B GB08504271A GB8504271A GB2160544B GB 2160544 B GB2160544 B GB 2160544B GB 08504271 A GB08504271 A GB 08504271A GB 8504271 A GB8504271 A GB 8504271A GB 2160544 B GB2160544 B GB 2160544B
Authority
GB
United Kingdom
Prior art keywords
hli
purifying
monoclonal antibody
monoclonal
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08504271A
Other versions
GB8504271D0 (en
GB2160544A (en
Inventor
Theophil Staehlin
Christian Stahli
Vincenzo Miggiano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1343/81A external-priority patent/CH651476A5/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB8504271D0 publication Critical patent/GB8504271D0/en
Publication of GB2160544A publication Critical patent/GB2160544A/en
Application granted granted Critical
Publication of GB2160544B publication Critical patent/GB2160544B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6866Interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GB08504271A 1981-02-27 1985-02-19 Monoclonal antibody to hli and its use for purifying hli Expired GB2160544B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1343/81A CH651476A5 (en) 1981-02-27 1981-02-27 Antibodies against proteins
CH777381 1981-12-04

Publications (3)

Publication Number Publication Date
GB8504271D0 GB8504271D0 (en) 1985-03-20
GB2160544A GB2160544A (en) 1985-12-24
GB2160544B true GB2160544B (en) 1986-06-18

Family

ID=25687398

Family Applications (2)

Application Number Title Priority Date Filing Date
GB08205667A Expired GB2111527B (en) 1981-02-27 1982-02-26 Monoclonal antibodies to human leucocyte interferon
GB08504271A Expired GB2160544B (en) 1981-02-27 1985-02-19 Monoclonal antibody to hli and its use for purifying hli

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB08205667A Expired GB2111527B (en) 1981-02-27 1982-02-26 Monoclonal antibodies to human leucocyte interferon

Country Status (15)

Country Link
AT (1) ATA74082A (en)
AU (2) AU561649B2 (en)
CA (1) CA1213226A (en)
DE (1) DE3206743A1 (en)
DK (1) DK86382A (en)
FR (1) FR2500754B1 (en)
GB (2) GB2111527B (en)
IE (1) IE52269B1 (en)
IL (1) IL65105A0 (en)
IT (1) IT1150201B (en)
LU (1) LU83978A1 (en)
NL (1) NL8200786A (en)
NZ (1) NZ199833A (en)
PH (1) PH18323A (en)
SE (2) SE8201226L (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8303165D0 (en) * 1983-02-04 1983-03-09 Secher D S Monoclonal antibody
DE3306060A1 (en) * 1983-02-22 1984-08-23 Boehringer Ingelheim International GmbH, 6507 Ingelheim NEW IMMUNGLOBULIN-PRODUCING HYBRID CELL LINES, THEIR USE AND METHOD FOR THE PRODUCTION THEREOF
JPS59172496A (en) * 1983-03-18 1984-09-29 Kyowa Hakko Kogyo Co Ltd Monoclonal antibody
FR2560212B1 (en) * 1984-02-24 1989-12-29 Unicet MONOCLONAL ANTIBODIES AGAINST INTERFERON A2 AND HYBRIDOMAS PRODUCING SUCH ANTIBODIES
GB9213135D0 (en) * 1992-06-20 1992-08-05 Atomic Energy Authority Uk A filter
US7087726B2 (en) 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI77877C (en) * 1979-04-20 1989-05-10 Technobiotic Ltd Process for the preparation and purification of human Le-shaped interferon protein.
AU7035781A (en) * 1980-04-11 1981-10-26 Secher, D. S. Monoclonal antibodies
DE3426077A1 (en) * 1984-07-14 1986-01-23 Dr. Karl Thomae Gmbh, 7950 Biberach MONOCLONAL ANTIBODIES AGAINST HUMANES IFN- (GAMMA), THESE ANTIBODY-PRODUCING HYBRID CELL LINES, USE OF THE NEW ANTIBODIES AND METHOD FOR THE PRODUCTION THEREOF
IL78444A (en) * 1986-04-08 1992-05-25 Yeda Res & Dev Human gamma interferon-specific receptor protein,antibody against said protein,and compositions containing said protein and antibody

Also Published As

Publication number Publication date
DE3206743A1 (en) 1982-09-23
IT1150201B (en) 1986-12-10
SE9000931D0 (en) 1990-03-15
FR2500754B1 (en) 1986-06-27
SE8201226L (en) 1982-09-24
GB2111527A (en) 1983-07-06
IL65105A0 (en) 1982-04-30
FR2500754A1 (en) 1982-09-03
GB8504271D0 (en) 1985-03-20
GB2111527B (en) 1986-01-15
SE9000931L (en) 1991-09-16
PH18323A (en) 1985-05-31
AU561649B2 (en) 1987-05-14
IT8219854A0 (en) 1982-02-25
DK86382A (en) 1982-08-28
NZ199833A (en) 1985-04-30
AU8077282A (en) 1982-09-02
ATA74082A (en) 1990-01-15
CA1213226A (en) 1986-10-28
NL8200786A (en) 1982-09-16
IE52269B1 (en) 1987-08-19
AU590688B2 (en) 1989-11-09
GB2160544A (en) 1985-12-24
AU6984487A (en) 1987-06-18
LU83978A1 (en) 1983-06-07

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Legal Events

Date Code Title Description
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee