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GB2142544A - Surgical implant - Google Patents

Surgical implant Download PDF

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Publication number
GB2142544A
GB2142544A GB08417032A GB8417032A GB2142544A GB 2142544 A GB2142544 A GB 2142544A GB 08417032 A GB08417032 A GB 08417032A GB 8417032 A GB8417032 A GB 8417032A GB 2142544 A GB2142544 A GB 2142544A
Authority
GB
United Kingdom
Prior art keywords
implant
sheet material
substrate
bonding
mesh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB08417032A
Other versions
GB8417032D0 (en
GB2142544B (en
Inventor
Samuel Medcraft
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomet UK Ltd
Original Assignee
Oec Orthopaedic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838318070A external-priority patent/GB8318070D0/en
Application filed by Oec Orthopaedic Ltd filed Critical Oec Orthopaedic Ltd
Priority to GB08417032A priority Critical patent/GB2142544B/en
Publication of GB8417032D0 publication Critical patent/GB8417032D0/en
Publication of GB2142544A publication Critical patent/GB2142544A/en
Application granted granted Critical
Publication of GB2142544B publication Critical patent/GB2142544B/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30907—Nets or sleeves applied to surface of prostheses or in cement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A61F2/36—Femoral heads ; Femoral endoprostheses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/02—Elements
    • C08K3/08—Metals

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

A method of making a surgical implant includes diffusion bonding to a surface of a substrate of a biocompatible material (eg titanium, titanium alloy, or cobalt-based alloy,) a mesh-form sheet material of e.g titanium, titanium alloy, or cobalt-based alloy so that there is provided on the surface a porous coating into which bone tissue can grow or surgical cement can enter.

Description

SPECIFICATION A surgical implant and a method of making the same According to one aspect of thq present invention, there is provided a surgical implant, comprising a substrate and a porous coating adhered to and extending over at least part of the surface of said substrate, said coating and said surface consisting of material substantially non-corrodible and nondegradable by body fluids, and said porous coating having been formed by bonding mesh-form sheet material to said surface.
According to another aspect of the present invention, there is provided a method of making a surgical implant, including bonding to at least part of a surface of a substrate, which surface is of material substantially non-corrodible and non-degradable by body fluids, mesh-form sheet material which is also substantially non-corrodible and non-degradable by body fluids, so that there is provided on said surface a porous coating.
In order that the invention may be clearly understood and readily carried into effect, examples thereof will now be described.
A metal substrate in the form of a surgical implant, for example a femoral prosthesis of a total hip, has applied to its surface, for example over an intramedullar stem thereof, one or more layers of meshform sheet material of a woven or expanded form, and the layer or layers is or are diffusion-bonded to the substrate. The mesh-form sheet material can be of titanium, a titanium alloy, a cobalt-based alloy, or another biologically compatible metal, in other words a metal which is substantially non-corrodible and non-degradable by body fluids.
Similarly, the substrate can be of titanium, a titanium alloy, a cobalt-based alloy, or another biologically compatible metal.
The hole size of the mesh and the pore size of the porous coating thereby formed on the substrate are sufficient to permit the growth of bone tissue into the coating and/or the entry of surgical cement into the coating.
The overall thickness of the layer(s) of sheet material is advantageously between 0.05 mm. and 1.00 mm., whilst the hole size of the mesh is advantageously between 0.10 mm. and 2.00 mm., the strand gauge of the mesh being as low as practicable.
The diffusion bonding of the sheet material to the substrate can be performed in a vacuum furnace under a suitable pressure and at a temperature of between 925 C and 9750C for between 0.5 and 3.0 hours.
In one particular example of the present invention, a substrate of titanium 6V4AL alloy had a single layer of expanded titanium CP115 applied thereto under a load of 4 lbsdin.2to ensure surface-to-surface contact. The layer thickness was 0.10 mm., the diamond shaped hole size of the mesh was 0.75 mm. smallest width and 1.00 mm. largest width, and the strand gauge was 0.12 mm. the assembly comprising the substrate and the sheet material was placed in a vacuum furnace which was pumped down to cold with a pressure of 1 x 10-4 millibars, the furnace temperature was raised to 9500C and maintained there for 11/2 hours, and then the furnace was vacuum cooled to 8500C with a pressure of 5 x 10-5 millibars, and thereafter the assembly was quenched under Argon at 1.05 bars to ambient.
In another particular example, the same materials and process were employed as in the above particular example, except that four layers of mesh each of 0.10 mm. thick were laid one upon another on the substrate.
In a further particular example, the same materials and process were employed except that the substrate was a cobalt-based alloy CoCrMo.
Attachment of the implant to the body can be achieved in any of the following ways: (1) By ingrowth of bone tissue and/orfibrous tissue into the multiplicity of pores provided in the coating, no cement or other fixation device being used.
(2) By incorporating adjuvant fixation devices to give implant stability until sufficient tissue ingrowth has occurred.
(3) By embedding in cement in some zones of the porous coating to give implant stability until suffi cienttissue ingrowth has occurred in the uncemented zones of the coating.
(4) By embedding all the porous coated areas into cement.

Claims (12)

1. A surgical implant, comprising a substrate and a porous coating adhered to and extending over at least part of the surface of said substrate, said coating and said surface consisting of material substantially non-corrodible and non-degradable by body fluids, and said porous coating having been formed by bonding mesh-form sheet material to said surface.
2. A method of making a surgical implant, including bonding to at least part of a surface of a substrate, which surface is of material substantially non-corrodible and non-degradable by body fluids, mesh-form sheet material which is also substantially non-corrodible and non-degradable by body fluids, so that there is provided on said surface a porous coating.
3. An implant as claimed in claim 1 or a method as claimed in claim 2, wherein said bonding comprises diffusion bonding.
4. An implant or a method as claimed in any preceding claim, wherein the overall thickness of said sheet material is between 0.05 mm. and 1.00 mm.
5. An implant or a method as claimed in any preceding claim, wherein the hole size of the mesh of said sheet material is between 0.10 mm. and 1.00 mm.
6. An implant or a method as claimed in any preceding claim, wherein said sheet material comprises a plurality of layers bonded to each other.
7. An implant or a method as claimed in claim 6, wherein the bonding of said layers to each other comprises diffusion bonding.
8. An implant or a method as claimed in any preceding claim, wherein said substrate and/or said sheet material comprise(s) any of titanium, a titanium alloy and a cobalt-based alloy.
9. An implant or a method as claimed In any preceding claim, wherein said sheet material is of a woven or expanded form.
10. A method as claimed in claims 3 and 8, wherein said diffusion bonding is performed at a temperature of between 9250C and 9750C for between 0.5 and 3.0 hours.
11. A surgical implant, substantially in accordance with any example hereinbefore described,
12. A method of making a surgical implant, substantially in accordance with any example hereinbefore described.
GB08417032A 1983-07-04 1984-07-04 Surgical implant Expired GB2142544B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB08417032A GB2142544B (en) 1983-07-04 1984-07-04 Surgical implant

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838318070A GB8318070D0 (en) 1983-07-04 1983-07-04 Surgical implant
GB08417032A GB2142544B (en) 1983-07-04 1984-07-04 Surgical implant

Publications (3)

Publication Number Publication Date
GB8417032D0 GB8417032D0 (en) 1984-08-08
GB2142544A true GB2142544A (en) 1985-01-23
GB2142544B GB2142544B (en) 1987-03-25

Family

ID=26286534

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08417032A Expired GB2142544B (en) 1983-07-04 1984-07-04 Surgical implant

Country Status (1)

Country Link
GB (1) GB2142544B (en)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0191152A1 (en) * 1985-01-08 1986-08-20 GebràœDer Sulzer Aktiengesellschaft Metallic implant for bones
US4660755A (en) * 1985-09-09 1987-04-28 Zimmer, Inc. Method for constructing a surgical implant
GB2183256A (en) * 1985-11-20 1987-06-03 Permelec Electrode Ltd Titanium composite having a porous surface and process for its production
GB2198356A (en) * 1986-12-05 1988-06-15 Haruyuki Kawahara Endosseous implants
US4829152A (en) * 1987-11-16 1989-05-09 Rostoker, Inc. Method of resistance welding a porous body to a substrate
US4889685A (en) * 1985-11-27 1989-12-26 Permelec Electrode Ltd. Process of producing titanium composite having a coil-shaped skeletal structure on the surface thereof
FR2635967A1 (en) * 1988-09-08 1990-03-09 Bristol Myers Co FIXING MECHANISM FOR ATTACHING AN ADDITIONAL ELEMENT TO AN IMPLANT
US5013324A (en) * 1987-08-24 1991-05-07 Zimmer, Inc. Prosthetic implant with wrapped porous surface
US5018285A (en) * 1987-08-24 1991-05-28 Zimmer, Inc. Method of constructing prosthetic implant with wrapped porous surface
US5080674A (en) * 1988-09-08 1992-01-14 Zimmer, Inc. Attachment mechanism for securing an additional portion to an implant
EP0566427A2 (en) * 1992-04-17 1993-10-20 Kyocera Corporation A prothesis and a method of making the same
US5323954A (en) * 1990-12-21 1994-06-28 Zimmer, Inc. Method of bonding titanium to a cobalt-based alloy substrate in an orthophedic implant device
US5496372A (en) * 1992-04-17 1996-03-05 Kyocera Corporation Hard tissue prosthesis including porous thin metal sheets
US5591234A (en) * 1993-02-01 1997-01-07 Axel Kirsch Post-surgery orthopedic covering
US5741257A (en) * 1993-02-01 1998-04-21 Kirsch; Axel Membrane for temporarily covering a bone surgery site
US7918382B2 (en) * 2002-06-18 2011-04-05 Zimmer Technology, Inc. Method for attaching a porous metal layer to a metal substrate
US8727203B2 (en) 2010-09-16 2014-05-20 Howmedica Osteonics Corp. Methods for manufacturing porous orthopaedic implants

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2059267A (en) * 1979-09-28 1981-04-23 Leuven Res & Dev Vzw Compound material for prosthetic devices
WO1983000282A1 (en) * 1981-07-27 1983-02-03 Battelle Development Corp Production of porous coating on a prosthesis
EP0071242A2 (en) * 1981-07-30 1983-02-09 CERAVER Société anonyme dite: Prosthetic stem composed of titanium or its alloys for the cementless fixation in a long bone
EP0075378A1 (en) * 1981-09-18 1983-03-30 Crucible Materials Corporation Prosthesis device and method of manufacture

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2059267A (en) * 1979-09-28 1981-04-23 Leuven Res & Dev Vzw Compound material for prosthetic devices
WO1983000282A1 (en) * 1981-07-27 1983-02-03 Battelle Development Corp Production of porous coating on a prosthesis
EP0071242A2 (en) * 1981-07-30 1983-02-09 CERAVER Société anonyme dite: Prosthetic stem composed of titanium or its alloys for the cementless fixation in a long bone
EP0075378A1 (en) * 1981-09-18 1983-03-30 Crucible Materials Corporation Prosthesis device and method of manufacture

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0191152A1 (en) * 1985-01-08 1986-08-20 GebràœDer Sulzer Aktiengesellschaft Metallic implant for bones
US4660755A (en) * 1985-09-09 1987-04-28 Zimmer, Inc. Method for constructing a surgical implant
US5034186A (en) * 1985-11-20 1991-07-23 Permelec Electrode Ltd. Process for providing titanium composite having a porous surface
GB2183256A (en) * 1985-11-20 1987-06-03 Permelec Electrode Ltd Titanium composite having a porous surface and process for its production
GB2183256B (en) * 1985-11-20 1989-10-04 Permelec Electrode Ltd Titanium composite having a porous surface and process for its production
US4889685A (en) * 1985-11-27 1989-12-26 Permelec Electrode Ltd. Process of producing titanium composite having a coil-shaped skeletal structure on the surface thereof
GB2198356A (en) * 1986-12-05 1988-06-15 Haruyuki Kawahara Endosseous implants
GB2198356B (en) * 1986-12-05 1991-04-24 Haruyuki Kawahara Endosseous implant having mesh pore structure
US5013324A (en) * 1987-08-24 1991-05-07 Zimmer, Inc. Prosthetic implant with wrapped porous surface
US5018285A (en) * 1987-08-24 1991-05-28 Zimmer, Inc. Method of constructing prosthetic implant with wrapped porous surface
US4829152A (en) * 1987-11-16 1989-05-09 Rostoker, Inc. Method of resistance welding a porous body to a substrate
BE1003104A5 (en) * 1988-09-08 1991-11-26 Bristol Myers Squibb Co FIXING MECHANISM FOR ATTACHING AN ADDITIONAL ELEMENT TO AN IMPLANT.
FR2635967A1 (en) * 1988-09-08 1990-03-09 Bristol Myers Co FIXING MECHANISM FOR ATTACHING AN ADDITIONAL ELEMENT TO AN IMPLANT
US5080674A (en) * 1988-09-08 1992-01-14 Zimmer, Inc. Attachment mechanism for securing an additional portion to an implant
US5323954A (en) * 1990-12-21 1994-06-28 Zimmer, Inc. Method of bonding titanium to a cobalt-based alloy substrate in an orthophedic implant device
EP0566427A2 (en) * 1992-04-17 1993-10-20 Kyocera Corporation A prothesis and a method of making the same
EP0566427A3 (en) * 1992-04-17 1994-06-15 Kyocera Corp A prothesis and a method of making the same
US5496372A (en) * 1992-04-17 1996-03-05 Kyocera Corporation Hard tissue prosthesis including porous thin metal sheets
US5591234A (en) * 1993-02-01 1997-01-07 Axel Kirsch Post-surgery orthopedic covering
US5741257A (en) * 1993-02-01 1998-04-21 Kirsch; Axel Membrane for temporarily covering a bone surgery site
US7918382B2 (en) * 2002-06-18 2011-04-05 Zimmer Technology, Inc. Method for attaching a porous metal layer to a metal substrate
US8191760B2 (en) 2002-06-18 2012-06-05 Zimmer Technology, Inc. Method for attaching porous metal layer to a metal substrate
US8985430B2 (en) 2002-06-18 2015-03-24 Zimmer, Inc. Method for attaching a porous metal layer to a metal substrate
US9656358B2 (en) 2002-06-18 2017-05-23 Zimmer, Inc. Method for attaching a porous metal layer to a metal substrate
US8727203B2 (en) 2010-09-16 2014-05-20 Howmedica Osteonics Corp. Methods for manufacturing porous orthopaedic implants

Also Published As

Publication number Publication date
GB8417032D0 (en) 1984-08-08
GB2142544B (en) 1987-03-25

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19970704