GB2139091A - Bone marrow cavity sealing plug - Google Patents
Bone marrow cavity sealing plug Download PDFInfo
- Publication number
- GB2139091A GB2139091A GB08408622A GB8408622A GB2139091A GB 2139091 A GB2139091 A GB 2139091A GB 08408622 A GB08408622 A GB 08408622A GB 8408622 A GB8408622 A GB 8408622A GB 2139091 A GB2139091 A GB 2139091A
- Authority
- GB
- United Kingdom
- Prior art keywords
- peg
- sealing
- bone marrow
- marrow cavity
- cavity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000001185 bone marrow Anatomy 0.000 title claims abstract description 34
- 238000007789 sealing Methods 0.000 title claims abstract description 27
- 239000001506 calcium phosphate Substances 0.000 claims abstract description 11
- -1 calcium phosphate compound Chemical class 0.000 claims abstract description 8
- 229910000389 calcium phosphate Inorganic materials 0.000 claims abstract description 7
- 235000011010 calcium phosphates Nutrition 0.000 claims abstract description 7
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 12
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 11
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 8
- 229910052587 fluorapatite Inorganic materials 0.000 claims description 6
- 229910000391 tricalcium phosphate Inorganic materials 0.000 claims description 5
- 235000019731 tricalcium phosphate Nutrition 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- GBNXLQPMFAUCOI-UHFFFAOYSA-H tetracalcium;oxygen(2-);diphosphate Chemical compound [O-2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GBNXLQPMFAUCOI-UHFFFAOYSA-H 0.000 claims description 4
- 229940078499 tricalcium phosphate Drugs 0.000 claims description 4
- 230000000903 blocking effect Effects 0.000 claims description 3
- JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 claims description 3
- 229940043256 calcium pyrophosphate Drugs 0.000 claims description 3
- 235000019821 dicalcium diphosphate Nutrition 0.000 claims description 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
- 125000004430 oxygen atom Chemical group O* 0.000 claims 1
- 210000004394 hip joint Anatomy 0.000 abstract description 12
- 210000000689 upper leg Anatomy 0.000 abstract description 10
- 230000000399 orthopedic effect Effects 0.000 abstract description 4
- 239000002639 bone cement Substances 0.000 description 18
- 230000037431 insertion Effects 0.000 description 8
- 210000000988 bone and bone Anatomy 0.000 description 7
- 210000001519 tissue Anatomy 0.000 description 7
- 238000003780 insertion Methods 0.000 description 6
- 238000012360 testing method Methods 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 3
- 229910019142 PO4 Inorganic materials 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000002093 peripheral effect Effects 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- 238000005245 sintering Methods 0.000 description 2
- 238000009864 tensile test Methods 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000000748 compression moulding Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 125000001153 fluoro group Chemical group F* 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 210000004197 pelvis Anatomy 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30721—Accessories
- A61F2/30723—Plugs or restrictors for sealing a cement-receiving space
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/30199—Three-dimensional shapes
- A61F2002/30205—Three-dimensional shapes conical
- A61F2002/3021—Three-dimensional shapes conical frustoconical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/30199—Three-dimensional shapes
- A61F2002/30224—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0067—Three-dimensional shapes conical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Compositions Of Oxide Ceramics (AREA)
Abstract
A sealing peg, used in the art of orthopedics to block a bone marrow cavity of a femur when a stem of an artificial hip joint is inserted into the bone marrow cavity and fixed therein, is made of a calcium phosphate compound and has a compressive strength of not less than 500 kg/cm<2>.
Description
SPECIFICATION
Sealing peg for blocking bone marrow cavity
Background of the invention
Field of the invention
The present invention relates to a sealing peg made of a calcium phosphate compound to be implanted into a bone marrow cavity to block the same.
Prior art
In the art of orthopedics, when it is required to substitute a joint at the linkage between the femur and the pelvis, an artifical hip joint having an integral stem is implanted with the stem inserted to be fixed in the bone marrow cavity of the femur. In general, a so-called bone cement is used for fixing the stem within the bone marrow cavity. It is, of course, desirous that the hip joint be implanted so that it is durable for long use.It is also preferred that the bone cement is applied onto the peripheral surface of the stem under sufficient pressure to fill recessed portions, such as notches, grooves or indents, provided over the peripheral surface of the stem and to adhere intimately in-between the recessed portions, thereby intimately adhering over the living bone tissue so as not to leave gaps or empty voids between the interior surface of the bone marrow cavity and the filling bone cement in order to exclude the risk that the humors enter into such gaps or voids.
However, in the conventional operation method wherein a bone cement is initially filled in the bone marrow cavity and then the stem of an artificial hip joint is inserted into the cavity filled with the bone cement, significant amount of bone cement is pushed off by the stem being inserted, resulting in deficiency of adhesion required for fixation. On the other hand, although it may be possible to fill up the bone marrow cavity entirely by the bone cement to achieve satisfactory fixation by adhesion, the quantity of bone cement required for such complete filling is extremely increased. This is not only uneconomical but also the dosage of extremely large amount of bone cement into the bone marrow cavity, which is one of the important organisms of the living body, is harmful to the living tissue since the bone cement is a foreign matter to the living tissue.
Alternatively, it has been proposed to cut off the spongiosus bone having required dimensions from the resected femoral caput and to insert the thus obtained spongiosus bone into the bone marrow cavity as a sealing peg. However, since the excision of spongiosus bone should be conducted as a part of the operation, the patient suffers increased strain as the time for operation is prolonged. Further, there are many cases for such patient where the quantity of spongiosus bone contained in the resected femoral caput of the patient under operation is too small to meet the requirement for such insertion even though more quantity of spongiosus bone is desired to be resected.
Under these circumstances, we have made efforts to eliminate the disadvantages involved in the conventional orthopedics and accomplished the present invention.
Objects and summary of the invention
A principal object of this invention is to provide a sealing peg to be inserted into a bone marrow cavity during the orthopedic operation, wherein an artificial hip joint is implanted, in order to block the bone marrow cavity to facilitate intimate adherence between the stem of the hip joint and the bone cement and between the bone cement and the interior peripheral wall of the bone marrow cavity, thereby to ensure firm fixation of the stem.
Another object of this invention is to provide a sealing peg having excellent adaptability or compatibility with living tissue without causing appreciable inflammation even when it is implanted into a bone marrow cavity of living body for a long time.
According to the invention, there is provided a sealing peg to be inserted into a bone marrow cavity for blocking the cavity, wherein the peg is made of a calcium phosphate compound and wherein the peg has a compressive strength of not less than 500 kg/cm2.
Description of the invention
The present invention will now be described in detail hereinbelow.
Although a variety of materials, including metals, organic substances and alumina, have been investigated as a material for a sealing peg to be inserted into a bone marrow cavity, it has been found that calcium phosphate compounds are the most favorable for such purpose since they have excellent adaptability or compatibility to living tissue when implanted in the bone marrow cavity for a long period.
The calcium phosphate compounds which may be used in the present invention include tricalcium phosphate (Ca3(PO4)2), hydroxyapatite (Ca5(PO4)30H), tetracalcium phosphate (Ca40(PO4)2), oxyapatite, calcium pyrophosphate (Ca2P207), fluoroapatite, hydroxyapatite derivatives each having one or more hydroxyl groups substituted by fluorine or oxygen ions, and mixtures thereof. It is preferred to use tricalcium phosphate, hydroxyapatite, tetracalcium phosphate, oxyapatite, fluoroapatite, or mixtures thereof, since they do not cause inflammation and have more excellent compatibility to living tissue.
The sealing peg according to the present invention is fixed at the position in the bone marrow cavity slightly deeper than the length of the stem of an artificial hip joint to block the bone marrow cavity, whereby the bone cement filled in the cavity is prevented from moving deeper in the cavity when the stem of the artificial hip joint is inserted therein. As a result, an increased pressure is developed within the cavity by the insertion of stem so that the filling bone cement is applied on the stem and the interior wall of the cavity under increased pressure to adhere intimately over the surface of the stem and the interior wall of the cavity to ensure firm fixation of the stem after it is solidified.
For this purpose, the sealing peg of the invention should be capable of being inserted into the bone marrow cavity and should be sustainable for bearing the pressure developed by the insertion of the artificial hip joint. Accordingly, the peg should have a compressive strength of not less than 500 kg/cm2, preferably not less than 800 kg/cm2, more preferably not less than 1200 kg/cm2. If the compressive strength of the sealing peg is less than 500 kg/cm2, it is apt to be broken during the insertion operation or it cannot bearthe pressure developed by the insertion of the stem.
The sealing peg of the invention should have shape and dimensions such that it can be fixed within the bone marrow cavity at the position slightly deeper than the length of the stem of the artificial hip joint and it can bear the pressure developed by insertion of the stem to be held fixedly at the implanted position.
Preferably, the peg has a contour of truncated conical shape or combination of a truncated cone and a cylinder. The peg of truncated conical shape, for example, is thrusted into the bone marrow cavity with its base surface, i.e. the face having larger area, facing upside and being engaged by suitable pushing means, such as a stainless pipe. For facilitating the insertion operation, the base or upside surface of the peg may be provided with a cylindrical projection for ensuring firm engagement with the end of the pushing pipe.
Alternatively, the base or upside surface of the peg may be provided with a central recess for receiving the end of pushing means having solid bar-like shape. When an artificial hip joint having a relatively short stem is implanted into a bone marrow cavity and when the cavity does not have to be cut into a cylindrical shape, a peg having a contour to be accommodated snugly within the shape of the bone marrow cavity may be prepared and fixed at a desired position. Principally, the shape of the sealing peg is not critical provided that the peg can bear the pressure developed by insertion of the stem of an artificial hip joint to be held in the fixed position.
The sealing peg of the invention may be prepared by sintering a calcium phosphate compound to obtain a sintered mass which is then machined to form a peg having desired shape and dimensions. Otherwise, powders of calcium phosphate may be molded by compression molding using a rubber press or may be formed using a lathe to have desired shape and dimensions, followed by sintering.
Examples of the invention
The present invention will be described in detail by referring to specific examples thereof.
Example 1 Five samples each having a truncated conical shape (Diameter of the Base: 10 mm, Diameter of the
Smaller Surface: 8 mm, Height: 5 mm) and made of hydroxyapatite, tricalcium phosphate and fluoroapatite having a variety of compressive strengths as shown in Table 1 were thrusted in bores each having a diameter of 9 mm drilled in the femurs of killed cattles. The number of broken pegs of each sample was checked, and the pegs which were thrusted without breakdown were pushed from the side reverse to the thrust direction by applying a force of 50 kg/cm2 to check the number of pegs pushed off from the bores. The compressive strength was determined using a test specimen of 5 mm~ x 5 mmL and using a universal testing machine (produced by Instron Engineering Corp.). The results are shown in Table 1.
TABLE 1
Number of Peg
Left after
Compressive Application of
Strength Unbroken Peg Pressure
Material (kg/cm2) Inserted Peg Unbroken Peg
Hydroxyapatite 400 4/5 0/4
500 5/5 3/5
800 5/5 4/5
1450 5/5 5/5
8200 5/5 5/5
Tricalcium 300 3/5 0/3
Phosphate 500 5/5 3/5
1010 5/5 4/5
1200 5/5 5/5
7630 5/5 5/5
Fluoroapatite 350 4/5 0/4
500 5/5 3/5
1200 5/5 5/5
9250 5/5 5/5
Example 2
A femoral caput at the vicinity of the end of the femur of a killed dog, the femur being frozen immediately after killing, was excised and a bone cement was filled in the thus exposed bone marrow cavity in which a stainless steel bar having a diameter of 5 mm and a length of 20 cm with the surface rugged like a file was inserted by 4 cm.A similar femur of a killed dog was drilled to remove the bone marrow and to form a bore of 5 mm in diameter extending along the length of the bone marrow. Into the thus formed bore implanted was a sample peg made of hydroxyapatite and having a diameter of base of 5.5 mm, a diameter of smaller surface of 4.5 mm and a height of 3 mm, the compressive strength of the peg being 1200 kg/cm2, and then the cavity blocked by the implanted peg was filled with the same bone cement. A stainless steel bar having a diameter of 5 mm and a length of 20 cm with the surface rugged like a file was inserted by 4 cm in the bone cement.
The free end, i.e. the end other than the end inserted into the bone marrow cavity of the femur, of each of stainless steel bars was clamped by a chuck of a universal testing machine (produced by Instron Engineering
Corp.) and the femur was clamped by the other chuck of the testing machine to subject each sample to tensile tests. The results of the tensile tests revealed that the sample without implanted with the hydroxyapatite peg was peeled off at the interface between the bone and the bone cement when the pulling force reached 30 kg/cm2, whereas the joining face of the sample implanted with the hydroxyapatite peg was not broken even when the pulling force reached 60 kg/cm2.
Example 3
Into a bone marrow of a femur of a living dog implanted was each of pegs having the dimensions of 3 mm x 3 mm x 3 mm and made respectivelyoftricalcium phosphate (Compressive Strength: 1200kg/cm2), hydroxyapatite (Compressive Strength: 1450 kg/cm2), tetracalcium phosphate (Compressive Strength: 1110 kg/cm2), fluoroapatite (Compressive Strength: 1200 kg/cm2) and a mixture of hydroxyapatite and oxyapatite (Compressive Strength: 2530 kg/cm2). The tissue at the vicinity of each of the implanted pegs was inspected after the lapse of six months to ascertain that no inflammation was observed in the tissue around the implanted peg. This result reveals that all of the tested pegs according to the invention has satisfactory adaptabilities or compatibilities with living body.
In the foregoing description, the present invention has been specifically disclosed by referring to some examples thereof. However, it should be appreciated that various modifications and variations can be easily made by those skilled in the art without departing from the spirit of the invention. It is, thus, intended to include all such modifications and variations within the wide scope of the present invention defined by the
Claims (12)
1. A sealing peg to be inserted into a bone marrow cavity for blocking the cavity, wherein the peg is made of a calcium phosphate compound, and wherein the peg has a compressive strength of not less than 500 kg/cm2.
2. A sealing peg according to claim 1, wherein the calcium phosphate compound is tricalcium phosphate, hydroxyapatite, tetracalcium phosphate, oxyapatatite, calcium pyrophosphate, fluoroapatite, a hydroxyapatite derivative having one or more hydroxyl groups substituted by fluroine or oxygen atoms, or a mixture thereof.
3. A sealing peg according to either preceding claim, wherein the peg has a compressive strength of not less than 800 kg/cm2.
4. A sealing peg according to claim 3, wherein the peg has a compressive strength of not less than 1200 kg/cm2.
5. A sealing peg according to any of claims 1 to 4, wherein the peg has a contour of generally truncated conical shape.
6. A sealing peg according to any of claims 1 to 4, wherein the peg includes a first segment of generally truncated conical shape and a second segment contiguous with the first segment and having a contour of generally cylindrical shape.
7. A sealing peg according to any preceding claim, wherein the peg is provided with engagement means for engaging with external means for thrusting the peg into the bone marrow cavity.
8. A sealing peg according to claim 7, wherein the external means is a tubular pipe and the engagement means is a cylindrical projection provided at the top face of the peg.
9. A sealing peg according to claim 7, wherein the external means is a solid bar and the engagement means is a concave recess formed in the top face of the peg.
10. A sealing peg according to claim 7, wherein the external means is a solid bar and the engagement means is a stub pipe extending from the top face of the peg for receiving the fore end of the solid bar.
11. A sealing peg according to any preceding claim, wherein the peg has a general contour to be accommodated snugly within the bone marrow cavity.
12. A sealing peg according to claim 1, substantially as described herein.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58061539A JPS59189841A (en) | 1983-04-09 | 1983-04-09 | Sealing gasket for filling bone carnal |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB8408622D0 GB8408622D0 (en) | 1984-05-16 |
| GB2139091A true GB2139091A (en) | 1984-11-07 |
| GB2139091B GB2139091B (en) | 1986-04-30 |
Family
ID=13174012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB08408622A Expired GB2139091B (en) | 1983-04-09 | 1984-04-04 | Bone marrow cavity sealing plug |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS59189841A (en) |
| CH (1) | CH662948A5 (en) |
| DE (1) | DE3412224A1 (en) |
| FR (1) | FR2543820B1 (en) |
| GB (1) | GB2139091B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2300810A (en) * | 1995-05-16 | 1996-11-20 | Asahi Optical Co Ltd | Bone marrow plug |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60150756A (en) * | 1984-01-18 | 1985-08-08 | 住友セメント株式会社 | Bone formation inducing material |
| JPH01166765A (en) * | 1987-12-23 | 1989-06-30 | Kobe Steel Ltd | Bone substitute and its preparation |
| DE8808701U1 (en) * | 1988-07-04 | 1989-08-03 | Mecron Medizinische Produkte Gmbh, 1000 Berlin | Endoprosthesis |
| DE3831657A1 (en) * | 1988-09-17 | 1990-03-22 | Boehringer Ingelheim Kg | DEVICE FOR THE OSTEOSYNTHESIS AND METHOD FOR THE PRODUCTION THEREOF |
| JPH07108303B2 (en) * | 1991-01-10 | 1995-11-22 | 晋輔 高杉 | Barhole button for skull valve fixation |
| DE4216496C2 (en) * | 1992-05-19 | 1994-09-22 | Werner Prof Dr Med Sattel | Use of a lead body for insertion into a bone cavity, in particular in the medullary cavity of a long bone |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2078696A (en) * | 1930-09-13 | 1937-04-27 | Ernest J Svenson | Hydraulic material working apparatus |
| DE2334643C2 (en) * | 1973-07-07 | 1974-09-19 | Friedrichsfeld Gmbh, Steinzeug- Und Kunststoffwerke, 6800 Mannheim | Aid for fastening an endoprosthesis |
| AT370710B (en) * | 1974-08-02 | 1983-04-25 | Sterling Drug Inc | METHOD FOR PRODUCING A POROUS, POLYCRYSTALLINE SINTER CERAMIC |
| GB1511859A (en) * | 1974-12-24 | 1978-05-24 | Friedrichsfeld Gmbh | Hip-joint endoprostheses |
| JPS5264199A (en) * | 1975-11-21 | 1977-05-27 | Tokyo Ika Shika Daigakuchiyou | Artificial bone and dental root with sintered apatite and method of producing same |
| US4097935A (en) * | 1976-07-21 | 1978-07-04 | Sterling Drug Inc. | Hydroxylapatite ceramic |
| JPS55130854A (en) * | 1979-03-31 | 1980-10-11 | Mitsubishi Mining & Cement Co | Method of burning hydroxyyapatite sintered body |
| GB2054383B (en) * | 1979-07-25 | 1983-08-03 | Univ Exeter | Plugs for the medullary canal of a bone |
| US4293962A (en) * | 1980-02-14 | 1981-10-13 | Zimmer Usa, Inc. | Bone plug inserting system |
| FR2485504A1 (en) * | 1980-06-30 | 1981-12-31 | Centre Nat Rech Scient | Sintered fluoro:apatite for bone prostheses - made with porous structure free from foreign phases |
-
1983
- 1983-04-09 JP JP58061539A patent/JPS59189841A/en active Pending
-
1984
- 1984-04-02 DE DE19843412224 patent/DE3412224A1/en active Granted
- 1984-04-02 CH CH1663/84A patent/CH662948A5/en not_active IP Right Cessation
- 1984-04-04 GB GB08408622A patent/GB2139091B/en not_active Expired
- 1984-04-06 FR FR8405534A patent/FR2543820B1/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2300810A (en) * | 1995-05-16 | 1996-11-20 | Asahi Optical Co Ltd | Bone marrow plug |
Also Published As
| Publication number | Publication date |
|---|---|
| CH662948A5 (en) | 1987-11-13 |
| JPS59189841A (en) | 1984-10-27 |
| FR2543820B1 (en) | 1989-06-02 |
| FR2543820A1 (en) | 1984-10-12 |
| GB8408622D0 (en) | 1984-05-16 |
| GB2139091B (en) | 1986-04-30 |
| DE3412224A1 (en) | 1984-10-11 |
| DE3412224C2 (en) | 1987-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19930404 |