[go: up one dir, main page]

GB2061934B - Mercaptoacyldihydropyrazole carboxylic acid derivatives - Google Patents

Mercaptoacyldihydropyrazole carboxylic acid derivatives

Info

Publication number
GB2061934B
GB2061934B GB8034001A GB8034001A GB2061934B GB 2061934 B GB2061934 B GB 2061934B GB 8034001 A GB8034001 A GB 8034001A GB 8034001 A GB8034001 A GB 8034001A GB 2061934 B GB2061934 B GB 2061934B
Authority
GB
United Kingdom
Prior art keywords
mercaptoacyldihydropyrazole
carboxylic acid
acid derivatives
derivatives
carboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8034001A
Other versions
GB2061934A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/088,425 external-priority patent/US4254267A/en
Priority claimed from US06/140,355 external-priority patent/US4266065A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB2061934A publication Critical patent/GB2061934A/en
Application granted granted Critical
Publication of GB2061934B publication Critical patent/GB2061934B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB8034001A 1979-10-25 1980-10-22 Mercaptoacyldihydropyrazole carboxylic acid derivatives Expired GB2061934B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/088,425 US4254267A (en) 1979-10-25 1979-10-25 Mercaptoacyldihydropyrazole carboxylic acid derivatives
US06/140,355 US4266065A (en) 1980-04-14 1980-04-14 Mercaptoacyldihydropyrazole carboxylic acid derivatives

Publications (2)

Publication Number Publication Date
GB2061934A GB2061934A (en) 1981-05-20
GB2061934B true GB2061934B (en) 1984-06-06

Family

ID=26778642

Family Applications (2)

Application Number Title Priority Date Filing Date
GB8034001A Expired GB2061934B (en) 1979-10-25 1980-10-22 Mercaptoacyldihydropyrazole carboxylic acid derivatives
GB08300874A Expired GB2129420B (en) 1979-10-25 1983-01-13 Pyrazoline carboxylic acids

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB08300874A Expired GB2129420B (en) 1979-10-25 1983-01-13 Pyrazoline carboxylic acids

Country Status (5)

Country Link
CA (1) CA1156236A (en)
DE (1) DE3040258A1 (en)
FR (2) FR2482099A1 (en)
GB (2) GB2061934B (en)
IT (1) IT1134037B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE454355B (en) * 1983-01-24 1988-04-25 Roussel Uclaf ACRYLIC ACID DERIVATIVES CONTAINING A FURYL, PYRANYL, BENZOFURANYL, OXAZOLYL OR ISOXAZOLYL GROUP, PROCEDURES FOR PREPARING THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEMSELVES
IT1179503B (en) * 1984-07-20 1987-09-16 Roussel Maestretti Spa New 4-furyl-4-oxo-butenoic acid derivs.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3013015A (en) * 1959-09-29 1961-12-12 Gen Aniline & Film Corp 1-substituted-2-pyrazoline-3-carbox-aldehyde dye intermediates
US3666772A (en) * 1970-02-26 1972-05-30 Carlisle Chemical Works Preparation of pyrazolines by cyclization of an azine
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4211786A (en) * 1979-03-08 1980-07-08 E. R. Squibb & Sons, Inc. Mercaptoacyldihydropyrazole carboxylic acid derivatives
US4288368A (en) * 1979-07-30 1981-09-08 E. R. Squibb & Sons, Inc. Dithioacylproline derivatives

Also Published As

Publication number Publication date
CA1156236A (en) 1983-11-01
GB2129420B (en) 1984-10-31
IT1134037B (en) 1986-07-24
GB2129420A (en) 1984-05-16
FR2474494B1 (en) 1983-06-17
FR2482099A1 (en) 1981-11-13
IT8025575A0 (en) 1980-10-24
FR2482099B1 (en) 1983-09-30
FR2474494A1 (en) 1981-07-31
GB2061934A (en) 1981-05-20
DE3040258A1 (en) 1981-05-21
GB8300874D0 (en) 1983-02-16

Similar Documents

Publication Publication Date Title
GB2057440B (en) Quinoline carboxylic acid derivatives
NZ189776A (en) Phenoxy-alkyl carboxylic acid derivatives
PT71744B (en) Substituted beta-carbolin-3-carboxylic acid derivatives
JPS5625146A (en) 33aminopropanesulfonic acid derivative
GB2055101B (en) Dithioacyldihydiopyrazole carboxylic acid derivatives dithioacylproline derivatives and related compounds
AU535924B2 (en) Carboxylic acid derivatives
GB2058773B (en) Cyclohexane carboxylic acid derivatives
ZA801016B (en) Mercaptoacyldihydropyrazole carboxylic acid derivatives
GB2117774B (en) Oximinoacetic acid derivatives
JPS5612365A (en) Mercaptoacylamino acid derivative
GB2055363B (en) Alkanoic acid derivatives
JPS5677262A (en) Mercaptoacyldihydropyrazolecarboxylic acid derivative
JPS5659742A (en) Nnacyllamino acid derivative
GB2053912B (en) Acylaminobenzoic acid derivatives
JPS55149251A (en) Substituted pyrrolidinylbenzoic acid derivative
GB2061934B (en) Mercaptoacyldihydropyrazole carboxylic acid derivatives
GB2025402B (en) Quinolopyran -4-one - 2 carboxylic acid derivatives
GB2093018B (en) 6,8-difluoro-quinoline carboxylic acid derivatives
ZA803734B (en) Acylaminobenzoic acid derivatives
JPS5615269A (en) Dihydronicotinic acid derivative
GB2051781B (en) Oxoamino acid derivatives
GB2125035B (en) 6b-halopenicillanic acid derivatives
JPS5640661A (en) Carboxylic acid derivative
ZA806246B (en) Oxayohimbane-carboxylic acid derivatives
JPS5625167A (en) Transs33*44oxoo4hhquinazolinee33yl**22propenic acid derivative

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee