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GB2034323B - Production of dna comprising the b hepatitis viral genome - Google Patents

Production of dna comprising the b hepatitis viral genome

Info

Publication number
GB2034323B
GB2034323B GB7943491A GB7943495A GB2034323B GB 2034323 B GB2034323 B GB 2034323B GB 7943491 A GB7943491 A GB 7943491A GB 7943495 A GB7943495 A GB 7943495A GB 2034323 B GB2034323 B GB 2034323B
Authority
GB
United Kingdom
Prior art keywords
dna
production
viral genome
hepatitis viral
hepatitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7943491A
Other versions
GB2034323A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Institut Pasteur
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM, Institut Pasteur filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Publication of GB2034323A publication Critical patent/GB2034323A/en
Priority to EP80304259A priority Critical patent/EP0030804B1/en
Priority to DE8080304259T priority patent/DE3065399D1/en
Priority to AT80304259T priority patent/ATE5076T1/en
Priority to GB8038588A priority patent/GB2065646B/en
Priority to US06/212,897 priority patent/US4343934A/en
Priority to ZA00807578A priority patent/ZA807578B/en
Priority to CA000366213A priority patent/CA1154760A/en
Priority to AU65151/80A priority patent/AU538458B2/en
Priority to IL61667A priority patent/IL61667A/en
Priority to PT72207A priority patent/PT72207B/en
Priority to YU3169/80A priority patent/YU40784B/en
Priority to MX80101456U priority patent/MX6561E/en
Priority to NZ195867A priority patent/NZ195867A/en
Priority to KR1019800004825A priority patent/KR840000156B1/en
Priority to ES497862A priority patent/ES8204484A1/en
Priority to PH24997A priority patent/PH17320A/en
Priority to DK537880A priority patent/DK157196C/en
Priority to IE2658/80A priority patent/IE50634B1/en
Priority to NO803848A priority patent/NO149242C/en
Priority to JP17967580A priority patent/JPS5697297A/en
Priority to AR283700A priority patent/AR229023A1/en
Priority to FI803959A priority patent/FI69470C/en
Priority to GR63714A priority patent/GR72757B/el
Application granted granted Critical
Publication of GB2034323B publication Critical patent/GB2034323B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GB7943491A 1978-12-18 1979-12-18 Production of dna comprising the b hepatitis viral genome Expired GB2034323B (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
EP80304259A EP0030804B1 (en) 1979-12-18 1980-11-27 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
DE8080304259T DE3065399D1 (en) 1979-12-18 1980-11-27 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
AT80304259T ATE5076T1 (en) 1979-12-18 1980-11-27 CRYSTALLINE-4,1',6'-TRICHLORO-4,1',6'-TRIDEOXYGALACTOSUCROSE.
GB8038588A GB2065646B (en) 1979-12-18 1980-12-02 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose
US06/212,897 US4343934A (en) 1979-12-18 1980-12-04 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
ZA00807578A ZA807578B (en) 1979-12-18 1980-12-04 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
CA000366213A CA1154760A (en) 1979-12-18 1980-12-05 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy- galactosucrose
AU65151/80A AU538458B2 (en) 1979-12-18 1980-12-08 Crystalline 4,1:,6:-trichloro-4,1:,61-trideoxygalactosucros
IL61667A IL61667A (en) 1979-12-18 1980-12-09 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose,method for the preparation thereof and comestible compositions containing it
PT72207A PT72207B (en) 1979-12-18 1980-12-16 Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose crystalline
YU3169/80A YU40784B (en) 1979-12-18 1980-12-16 Process for preparing 4,1'6',-trichloro-4,1,6'-trideoxy-galaceto saccharose
MX80101456U MX6561E (en) 1979-12-18 1980-12-16 PROCEDURE FOR THE PREPARATION OF 4,1,6-TRICHLORO-4,1 ', 6'-TRIDESOXI-GALACTOSACAROSA CRISTALINA ANHIDRA
NZ195867A NZ195867A (en) 1979-12-18 1980-12-17 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose and use as sweetener
KR1019800004825A KR840000156B1 (en) 1979-12-18 1980-12-17 Crystalline 4,1',6',trichloro,4,1',6' trideoxi-galactosucrose
ES497862A ES8204484A1 (en) 1979-12-18 1980-12-17 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose.
PH24997A PH17320A (en) 1979-12-18 1980-12-17 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
DK537880A DK157196C (en) 1979-12-18 1980-12-17 Crystalline 4,1 ', 6'-TRICHLOR-4,1', 6
IE2658/80A IE50634B1 (en) 1979-12-18 1980-12-17 Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
NO803848A NO149242C (en) 1979-12-18 1980-12-18 Crystalline, 4,1`, 6`-TRIKLOR-4,1`, 6`-TRIDEOXYGALACTOSUCROSE
JP17967580A JPS5697297A (en) 1979-12-18 1980-12-18 Crystalline 4*1**6**trichloroo4*1**6** trideoxygalactose
AR283700A AR229023A1 (en) 1979-12-18 1980-12-18 NEW CRYSTALLINE FORM OF 4.1 ', 6'-TRICLORO-4,1', 6'-TRIDESOXIGALACTO SUCROSA USEFUL AS A SWEETENER AND CONTAINING SWEETENING COMPOSITIONS
FI803959A FI69470C (en) 1979-12-18 1980-12-18 CRYSTALS 4,1 ', 6'-TRICHLORO-4,1', 6'-TRIDEOXI-GALACTOSACKAROS
GR63714A GR72757B (en) 1979-12-18 1980-12-18

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7835588A FR2444713A1 (en) 1978-12-18 1978-12-18 PROCESS FOR PRODUCING DNA COMPRISING THE GENOME OF HEPATITIS B VIRUS AND VECTOR COMPRISING SAME

Publications (2)

Publication Number Publication Date
GB2034323A GB2034323A (en) 1980-06-04
GB2034323B true GB2034323B (en) 1983-01-12

Family

ID=9216265

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7943491A Expired GB2034323B (en) 1978-12-18 1979-12-18 Production of dna comprising the b hepatitis viral genome

Country Status (6)

Country Link
BE (1) BE880670A (en)
CH (1) CH646456A5 (en)
DE (1) DE2950995A1 (en)
FR (1) FR2444713A1 (en)
GB (1) GB2034323B (en)
OA (1) OA06416A (en)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2480779B2 (en) * 1979-08-30 1986-07-18 Anvar VECTOR CONTAINING A NUCLEOTIDE SEQUENCE OF THE SURFACE ANTIGEN OF HEPATITIS B VIRUS AND METHOD FOR MANUFACTURING AN IMMUNOGENIC MOLECULE USING THE SAME
NZ192465A (en) * 1978-12-22 1983-09-30 Biogen Nv Recombinant dna molecule comprising gene coding for polypeptide displaying hbv (hepatitis b virus) antigenicity usesthereof
US6297355B1 (en) 1978-12-22 2001-10-02 Biogen, Inc. Polypeptides displaying HBV antigenicity or hbv antigen specificity
EP0182442B2 (en) * 1978-12-22 1996-04-03 Biogen, Inc. Recombinant DNA molecules and their method of production
US5196194A (en) * 1979-05-24 1993-03-23 The Regents Of The University Of California Vaccines containing Hepatitis B S-protein
IE52036B1 (en) * 1979-05-24 1987-05-27 Univ California Non-passageable viruses
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
US6835557B1 (en) 1980-01-08 2004-12-28 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides
DE3176404D1 (en) * 1980-04-22 1987-10-08 Pasteur Institut Vaccine against viral hepatitis b, method and transformed eucaryotic cells for the preparation of this vaccine
US4393133A (en) * 1980-06-12 1983-07-12 The Wistar Institute Of Anatomy And Biology Human hepatoma derived cell line, process for preparation thereof, and uses therefor
US5145782A (en) * 1980-12-08 1992-09-08 The Regents Of The University Of California DNA expression vector suitable for direct expression of a foreign gene
US4446237A (en) * 1981-03-27 1984-05-01 Life Technologies, Inc. Method for detection of a suspect viral deoxyribonucleic acid in an acellular biological fluid
EP0062286A1 (en) * 1981-03-31 1982-10-13 Albert Einstein College Of Medicine Of Yeshiva University Diagnostic test for hepatitis B virus
US4711955A (en) * 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
US4769238A (en) 1981-08-04 1988-09-06 The Regents Of The University Of California Synthesis of human virus antigens by yeast
ZW18282A1 (en) 1981-08-31 1983-03-23 Genentech Inc Preparation of polypeptides in vertebrate cell culture
US4803164A (en) * 1981-08-31 1989-02-07 Genentech, Inc. Preparation of hepatitis b surface antigen in yeast
AU8746582A (en) * 1981-09-02 1983-03-10 Biogen N.V. Hepatitis b virus e type antigen
FI63596C (en) * 1981-10-16 1983-07-11 Orion Yhtymae Oy MICROBIA DIAGNOSIS FOERFARANDE SOM GRUNDAR SIG PAO SKIKTSHYBRIDISERING AV NUCLEINSYROR OCH VID FOERFARANDET ANVAENDA KOMBINATIONER AV REAGENSER
US4480040A (en) * 1981-12-03 1984-10-30 The United States Of America As Represented By The Secretary Of Agriculture Sensitive and rapid diagnosis of viroid diseases and viruses
JPS5931799A (en) * 1982-08-16 1984-02-20 Science & Tech Agency Recombinant plasmid and preparation of transformed yeast and hepatitis virus b surface antigen using the same
USRE35491E (en) * 1982-11-04 1997-04-08 The Regents Of The University Of California Methods and compositions for detecting human tumors
US4699877A (en) * 1982-11-04 1987-10-13 The Regents Of The University Of California Methods and compositions for detecting human tumors
US4820642A (en) * 1983-04-04 1989-04-11 The Regents Of The University Of California Amplified expression vector
FR2560995B1 (en) * 1984-03-07 1988-02-19 Pasteur Institut REAGENTS AND KITS FOR THE QUANTITATIVE DETERMINATION OF A VIRAL NUCLEIC ACID IN A BIOLOGICAL MEDIUM AND METHOD FOR DETERMINING SUCH A VIRAL NUCLEIC ACID
US6607727B1 (en) 1991-08-26 2003-08-19 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus
US5780036A (en) * 1991-08-26 1998-07-14 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepattis B virus
CA2124928C (en) * 1991-12-23 2003-06-17 Bruce D. Irvine Hbv amplifier probes for use in solution phase sandwich hybridization assays
US6235288B1 (en) 1992-08-26 2001-05-22 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus
WO2000077179A2 (en) 1999-06-16 2000-12-21 Icos Corporation Human poly(adp-ribose) polymerase 2 materials and methods
AU2002241556B2 (en) 2000-11-01 2007-07-19 Elusys Therapeutics, Inc. Method of producing bispecific molecules by protein trans-splicing
EP2631294A3 (en) 2005-04-29 2013-11-20 The Rockefeller University Human microRNAs and methods for inhibiting same
DK1928492T3 (en) 2005-09-01 2011-06-06 Celgene Corp Immunological applications of immunomodulatory compounds for vaccine and therapy for infectious diseases
US9931377B2 (en) 2007-06-27 2018-04-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cell expressing complexes of IL-15 and IL-15Ralpha
AU2009279682B2 (en) 2008-08-04 2015-01-22 University Of Miami STING (stimulator of interferon genes), a regulator of innate immune responses
US8691502B2 (en) 2008-10-31 2014-04-08 Tremrx, Inc. T-cell vaccination with viral vectors via mechanical epidermal disruption
EP2389443B1 (en) 2009-01-23 2018-11-14 Roger Williams Hospital Retroviral vectors encoding multiple highly homologous non-viral polypeptides and the use of same
US9216189B2 (en) 2010-01-25 2015-12-22 Icahn School Of Medicine At Mount Sinai Antibodies which bind type I cannabinoid receptor/angiotensis II receptor heteromers
WO2012151272A2 (en) 2011-05-02 2012-11-08 Tremrx, Inc. T-cell vaccination with viral vectors via mechanical epidermal disruption
JP6253596B2 (en) 2012-02-16 2017-12-27 ザ ペン ステイト リサーチ ファンデーション Acyl coenzyme A: a method for identifying an inhibitor of expression, function or activity of lysocardiolipin acyltransferase 1 (ALCAT1)
JP6486272B2 (en) 2012-09-07 2019-03-20 マサチューセッツ・アイ・アンド・イア・インファーマリー Methods and compositions for hair cell and / or feeder cell regeneration
JP6359019B2 (en) 2012-10-24 2018-07-18 ノバルティス アーゲー IL-15Rα type, cells expressing IL-15Rα type, and therapeutic use of IL-15Rα and IL-15 / IL-15Rα complex
WO2016018920A1 (en) 2014-07-29 2016-02-04 Admune Therapeutics Llc Il-15 and il-15ralpha heterodimer dose escalation regimens for treating conditions
WO2016069906A1 (en) 2014-10-29 2016-05-06 Massachusetts Eye And Ear Infirmary Efficient delivery of therapeutic molecules to cells of the inner ear
US10258697B2 (en) 2014-10-29 2019-04-16 Massachusetts Eye And Ear Infirmary Efficient delivery of therapeutic molecules in vitro and in vivo
US20220118077A1 (en) 2018-09-11 2022-04-21 Shanghai Public Health Clinical Center Immunogen for broad-spectrum influenza vaccine and application thereof
US11786592B2 (en) 2021-05-19 2023-10-17 The University Of Hong Kong Compositions of cardiolipin adjuvants and methods of use thereof
WO2023077147A2 (en) 2021-11-01 2023-05-04 Pellis Therapeutics, Inc. T-cell vaccines for patients with reduced humoral immunity
WO2023220283A1 (en) 2022-05-12 2023-11-16 Pellis Therapeutics, Inc. Poxvirus adjuvant for t-cell vaccination

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521032A (en) * 1974-08-08 1978-08-09 Ici Ltd Biological treatment
DE2712615A1 (en) * 1977-03-18 1978-09-21 Max Planck Gesellschaft PROCESS FOR MANUFACTURING FILAMENTOES PHAGEN AS A VECTOR FOR SYNTHETIC RECOMBINATES

Also Published As

Publication number Publication date
BE880670A (en) 1980-06-18
FR2444713B1 (en) 1981-02-06
DE2950995C2 (en) 1991-05-02
OA06416A (en) 1981-09-30
GB2034323A (en) 1980-06-04
CH646456A5 (en) 1984-11-30
FR2444713A1 (en) 1980-07-18
DE2950995A1 (en) 1980-07-24

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Legal Events

Date Code Title Description
CTFF Supplementary protection certificate filed

Free format text: SPC/GB93/162, 930702

CTFG Supplementary protection certificate granted

Free format text: SPC/GB93/162, 930702 SECOND APPLICANT:INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, EXPIRES:YYYYMMDD

CTFW Application to withdraw or offer to surrender a supplementary protection certificate

Free format text: SPC/GB93/162

PE20 Patent expired after termination of 20 years

Effective date: 19991217