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GB201109231D0 - Pharmaceutical composition comprising bosentan - Google Patents

Pharmaceutical composition comprising bosentan

Info

Publication number
GB201109231D0
GB201109231D0 GBGB1109231.9A GB201109231A GB201109231D0 GB 201109231 D0 GB201109231 D0 GB 201109231D0 GB 201109231 A GB201109231 A GB 201109231A GB 201109231 D0 GB201109231 D0 GB 201109231D0
Authority
GB
United Kingdom
Prior art keywords
pharmaceutical composition
bosentan
diluent
filler
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GBGB1109231.9A
Other versions
GB2491205A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfred E Tiefenbacher GmbH and Co KG
Original Assignee
Alfred E Tiefenbacher GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfred E Tiefenbacher GmbH and Co KG filed Critical Alfred E Tiefenbacher GmbH and Co KG
Priority to GB1109231.9A priority Critical patent/GB2491205A/en
Publication of GB201109231D0 publication Critical patent/GB201109231D0/en
Publication of GB2491205A publication Critical patent/GB2491205A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)

Abstract

A stable solid pharmaceutical composition comprises: - bosentan or a pharmaceutically acceptable salt thereof; - a first diluent or filler which is a cellulose derivative; - a second diluent or filler which is different from the first diluent. Preferably the second diluents is starch or lactose. Also disclosed is a process for manufacturing the inventive pharmaceutical composition, wherein a granulate is prepared from a powder mixture of the ingredients, compressing the mixture and applying a coating thereto.
GB1109231.9A 2011-05-25 2011-05-25 Composition comprising bosentan and diluents Withdrawn GB2491205A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1109231.9A GB2491205A (en) 2011-05-25 2011-05-25 Composition comprising bosentan and diluents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1109231.9A GB2491205A (en) 2011-05-25 2011-05-25 Composition comprising bosentan and diluents

Publications (2)

Publication Number Publication Date
GB201109231D0 true GB201109231D0 (en) 2011-07-13
GB2491205A GB2491205A (en) 2012-11-28

Family

ID=44310740

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1109231.9A Withdrawn GB2491205A (en) 2011-05-25 2011-05-25 Composition comprising bosentan and diluents

Country Status (1)

Country Link
GB (1) GB2491205A (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19743681A1 (en) * 1997-10-02 1999-04-08 Knoll Ag Use of endothelin receptor antagonists to prevent transplant rejection
CN101404981A (en) * 2006-03-13 2009-04-08 恩希赛弗制药公司 Methods and compositions for treatment of diastolic heart failure

Also Published As

Publication number Publication date
GB2491205A (en) 2012-11-28

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)