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GB201008720D0 - RxLR-leader peptides and protein translocation - Google Patents

RxLR-leader peptides and protein translocation

Info

Publication number
GB201008720D0
GB201008720D0 GBGB1008720.3A GB201008720A GB201008720D0 GB 201008720 D0 GB201008720 D0 GB 201008720D0 GB 201008720 A GB201008720 A GB 201008720A GB 201008720 D0 GB201008720 D0 GB 201008720D0
Authority
GB
United Kingdom
Prior art keywords
rxlr
proteins
protein translocation
leader peptides
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1008720.3A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Aberdeen
Original Assignee
University of Aberdeen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Aberdeen filed Critical University of Aberdeen
Priority to GBGB1008720.3A priority Critical patent/GB201008720D0/en
Publication of GB201008720D0 publication Critical patent/GB201008720D0/en
Priority to PCT/GB2011/000801 priority patent/WO2011148135A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

This invention relates to proteins comprising sequence elements found in the AVR3a protein from the potato late blight pathogen Phytophthora infestans. The present invention also related to derivatives of these proteins and methods of modulating their function and activity. The invention describes a number of uses of these proteins, including the use to direct protein translocation into eukaryotic cells.
GBGB1008720.3A 2010-05-25 2010-05-25 RxLR-leader peptides and protein translocation Ceased GB201008720D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB1008720.3A GB201008720D0 (en) 2010-05-25 2010-05-25 RxLR-leader peptides and protein translocation
PCT/GB2011/000801 WO2011148135A1 (en) 2010-05-25 2011-05-25 Translocation across eukaryotic cell membranes based on oomycete protein sequence motifs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1008720.3A GB201008720D0 (en) 2010-05-25 2010-05-25 RxLR-leader peptides and protein translocation

Publications (1)

Publication Number Publication Date
GB201008720D0 true GB201008720D0 (en) 2010-07-07

Family

ID=42341284

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1008720.3A Ceased GB201008720D0 (en) 2010-05-25 2010-05-25 RxLR-leader peptides and protein translocation

Country Status (2)

Country Link
GB (1) GB201008720D0 (en)
WO (1) WO2011148135A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201309664D0 (en) * 2013-05-30 2013-07-17 Univ Aberdeen Fish vaccine
GB201808910D0 (en) 2018-05-31 2018-07-18 Univeristy Court Of The Univ Of Aberdeen Translocation into eukaryotic cells
CN111718402A (en) * 2019-09-20 2020-09-29 山东农业大学 A Phytophthora capsicum effector protein and its encoding gene and application
CN110904124B (en) * 2019-10-25 2020-12-11 华南农业大学 Avirulence Gene AvrPit of Rice Blast Fungus and Its Application
CN112979773B (en) * 2021-03-16 2021-12-28 南京林业大学 Phytophthora camphora effector protein RxLR29 and its application
KR102727673B1 (en) * 2021-09-29 2024-11-07 서울대학교산학협력단 dsRNA targeting Avr8 for inhibiting Phytophthora infestans proliferation and uses thereof
CN116286850B (en) * 2022-08-19 2024-08-06 中国农业大学 A negative regulatory gene for resistance to rice false smut and its use

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3710795A (en) 1970-09-29 1973-01-16 Alza Corp Drug-delivery device with stretched, rate-controlling membrane
NL8200523A (en) 1982-02-11 1983-09-01 Univ Leiden METHOD FOR TRANSFORMING IN VITRO PLANT PROTOPLASTS WITH PLASMIDE DNA.
ATE52800T1 (en) 1983-01-13 1990-06-15 Max Planck Gesellschaft METHOD OF INTRODUCING EXPRESSIONABLE GENES INTO PLANT CELL GENOMES AND HYBRID TI PLASMID VECTORS CONTAINING AGROBACTERIUM STRAINS USABLE IN THIS METHOD.
CA1280081C (en) 1984-09-24 1991-02-12 Calgene, Inc. Plant cell microinjection technique
US5100792A (en) 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
EP0265502A1 (en) 1986-04-30 1988-05-04 Boyce Thompson Institute For Plant Research, Inc. Electric field mediated dna transformation of plant cells and organelles
US5004863B2 (en) 1986-12-03 2000-10-17 Agracetus Genetic engineering of cotton plants and lines
EP0574356A1 (en) 1987-05-05 1993-12-15 Sandoz Ag Plant tissue transformation
EP0331083A3 (en) 1988-03-02 1990-11-28 Schweizerische Eidgenossenschaft Eidgenössische Technische Hochschule (Eth) Method for the production of transgenic plants
US5108921A (en) 1989-04-03 1992-04-28 Purdue Research Foundation Method for enhanced transmembrane transport of exogenous molecules
ATE130371T1 (en) 1989-12-19 1995-12-15 Ciba Geigy Ag METHOD AND DEVICE FOR THE GENETIC TRANSFORMATION OF CELLS.
DE4005152A1 (en) 1990-02-17 1991-08-22 Guenter Prof Dr Kahl Transforming plant protoplast(s) with DNA-histone complex - providing high and reproducible transfer rate, and expression of foreign genes
CA2036935A1 (en) 1990-02-26 1991-08-27 Paul Christou Plant transformation process with early identification of germ line transformation events
US5932782A (en) 1990-11-14 1999-08-03 Pioneer Hi-Bred International, Inc. Plant transformation method using agrobacterium species adhered to microprojectiles
NZ239977A (en) 1990-11-14 1993-08-26 Pioneer Hi Bred Int Transforming plants by the use of agrobacterium
DE69133512T2 (en) 1990-11-23 2006-09-28 Bayer Bioscience N.V. Process for the transformation of monocotyledonous plants
WO1994000583A1 (en) 1992-06-23 1994-01-06 South Dakota State University Transformation of plants by direct injection of dna
EP2291188A4 (en) * 2008-05-19 2012-08-22 Virginia Tech Intell Prop COMPOSITIONS AND METHOD FOR PROTECTION OF CELLS BY BLOCKING THE INPUT OF PATHOGENIC PROTEINS

Also Published As

Publication number Publication date
WO2011148135A1 (en) 2011-12-01

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)