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GB2006185A - Method for producing purine arabinosides - Google Patents

Method for producing purine arabinosides

Info

Publication number
GB2006185A
GB2006185A GB7832560A GB7832560A GB2006185A GB 2006185 A GB2006185 A GB 2006185A GB 7832560 A GB7832560 A GB 7832560A GB 7832560 A GB7832560 A GB 7832560A GB 2006185 A GB2006185 A GB 2006185A
Authority
GB
United Kingdom
Prior art keywords
producing purine
purine arabinosides
arabinosides
purine
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7832560A
Other versions
GB2006185B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9576677A external-priority patent/JPS5432695A/en
Priority claimed from JP15873877A external-priority patent/JPS5492695A/en
Priority claimed from JP180278A external-priority patent/JPS5495793A/en
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of GB2006185A publication Critical patent/GB2006185A/en
Application granted granted Critical
Publication of GB2006185B publication Critical patent/GB2006185B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

A 9-( beta -D-arabinofuranosyl) purine which is optionally substituted at the 2,6-and/or 8-position can be produced by reacting an arabinose donor with a purine source in the presence of an enzyme capable of effecting transarabinosylation.
GB7832560A 1977-08-10 1978-08-08 Method for producing purine arabinosides Expired GB2006185B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP9576677A JPS5432695A (en) 1977-08-10 1977-08-10 Preparation of purine arabinosides
JP15873877A JPS5492695A (en) 1977-12-28 1977-12-28 2-substituted hypoxanthinearabinoside and its preparation
JP180278A JPS5495793A (en) 1978-01-11 1978-01-11 Preparation of purine arabinoside

Publications (2)

Publication Number Publication Date
GB2006185A true GB2006185A (en) 1979-05-02
GB2006185B GB2006185B (en) 1982-04-28

Family

ID=27275082

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7832560A Expired GB2006185B (en) 1977-08-10 1978-08-08 Method for producing purine arabinosides

Country Status (5)

Country Link
CA (1) CA1120876A (en)
DE (1) DE2835151A1 (en)
FR (1) FR2400033A1 (en)
GB (1) GB2006185B (en)
NL (1) NL7808321A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1464708A1 (en) * 2003-04-03 2004-10-06 Pro. Bio. Sint. S.p.A. A process for the preparation of fludarabine phosphate from 2-fluoroadenine
RU2563257C1 (en) * 2014-11-07 2015-09-20 Федеральное государственное бюджетное учреждение науки Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова РАН (ИБХ РАН) METHOD OF PRODUCING 9-(BETA-D-ARABINOFURANOSYL)-6-(Nα-L-SERYLAMIDO)-2-CHLOROPURINE

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0275065B1 (en) * 1982-04-01 1991-06-19 Yamasa Shoyu Kabushiki Kaisha New phosphorylase producing microorganism

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3269917A (en) * 1963-03-18 1966-08-30 Takeda Chemical Industries Ltd Process for producing purine-nucleosides
GB1159290A (en) * 1966-12-30 1969-07-23 Parke Davis & Co Fermentation process for 9-(beta-D-Arabinofuranosyl) Adenine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1464708A1 (en) * 2003-04-03 2004-10-06 Pro. Bio. Sint. S.p.A. A process for the preparation of fludarabine phosphate from 2-fluoroadenine
WO2004087939A1 (en) * 2003-04-03 2004-10-14 Pro.Bio.Sint. S.P.A. A process for the preparation of fludarabine phosphate from 2-fluoroadenine and fludarabine phosphate salts with amines or ammonia
RU2563257C1 (en) * 2014-11-07 2015-09-20 Федеральное государственное бюджетное учреждение науки Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова РАН (ИБХ РАН) METHOD OF PRODUCING 9-(BETA-D-ARABINOFURANOSYL)-6-(Nα-L-SERYLAMIDO)-2-CHLOROPURINE

Also Published As

Publication number Publication date
FR2400033A1 (en) 1979-03-09
NL7808321A (en) 1979-02-13
GB2006185B (en) 1982-04-28
CA1120876A (en) 1982-03-30
DE2835151C2 (en) 1988-07-14
DE2835151A1 (en) 1979-02-22
FR2400033B1 (en) 1982-07-30

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 19980807