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GB1551993A - Pharmacologiclly active derivatives of 1 alkyl 4-phenylpiperazines and the preparation thereof - Google Patents

Pharmacologiclly active derivatives of 1 alkyl 4-phenylpiperazines and the preparation thereof

Info

Publication number
GB1551993A
GB1551993A GB3909676A GB3909676A GB1551993A GB 1551993 A GB1551993 A GB 1551993A GB 3909676 A GB3909676 A GB 3909676A GB 3909676 A GB3909676 A GB 3909676A GB 1551993 A GB1551993 A GB 1551993A
Authority
GB
United Kingdom
Prior art keywords
pharmacologiclly
phenylpiperazines
alkyl
preparation
active derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3909676A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Malesci Instituto Farmacobiologico SpA
Original Assignee
Malesci Instituto Farmacobiologico SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Malesci Instituto Farmacobiologico SpA filed Critical Malesci Instituto Farmacobiologico SpA
Priority to GB3909676A priority Critical patent/GB1551993A/en
Publication of GB1551993A publication Critical patent/GB1551993A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
GB3909676A 1976-09-21 1976-09-21 Pharmacologiclly active derivatives of 1 alkyl 4-phenylpiperazines and the preparation thereof Expired GB1551993A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3909676A GB1551993A (en) 1976-09-21 1976-09-21 Pharmacologiclly active derivatives of 1 alkyl 4-phenylpiperazines and the preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3909676A GB1551993A (en) 1976-09-21 1976-09-21 Pharmacologiclly active derivatives of 1 alkyl 4-phenylpiperazines and the preparation thereof

Publications (1)

Publication Number Publication Date
GB1551993A true GB1551993A (en) 1979-09-05

Family

ID=10407614

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3909676A Expired GB1551993A (en) 1976-09-21 1976-09-21 Pharmacologiclly active derivatives of 1 alkyl 4-phenylpiperazines and the preparation thereof

Country Status (1)

Country Link
GB (1) GB1551993A (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2543139A1 (en) * 1983-03-22 1984-09-28 Cerm Cent Europ Rech Mauvernay (1-ALCOXY 2-AMINO) ETHYL PYRIDINE OR PYRAZINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
DE3425477A1 (en) * 1983-07-11 1985-01-31 Malesci S.p.A. Istituto Farmacobiologico, Florenz/Firenze METHOD FOR THE PRODUCTION OF 1-PYRIDYLALKYL-4-ARYLPIPERAZINES USED AS BLOOD PRESSURE-REDUCING COMPOUNDS AND THEIR SEPARATION THEREOF, AND THE STEREOISOMERS OBTAINED THEREFORE
US4829065A (en) * 1987-04-24 1989-05-09 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US4935417A (en) * 1987-04-24 1990-06-19 Syntex Pharmaceuticals Ltd. Sustituted imidazolyl-alkyl-piperazine and -diazepine derivatives for treating cerebrovascular disease
US4973591A (en) * 1988-10-21 1990-11-27 Syntex Pharmaceuticals, Ltd. Parenteral formulations of 1-diphenylmethyl-4-((2-(4-methylphenyl)-5-methyl-1H-imidazol-4-yl)methyl)piperazine
US5010075A (en) * 1987-04-24 1991-04-23 Syntex Pharmaceuticals Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US5043447A (en) * 1987-04-24 1991-08-27 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US5063220A (en) * 1988-10-21 1991-11-05 Syntex Pharmaceuticals, Ltd. Parenteral formulations of 1-diphenylmethyl-4-((2-(4-methylphenyl)-5-methyl-1H-imidazol-4-yl)methyl)piperazine
US5089497A (en) * 1990-09-20 1992-02-18 Warner-Lambert Company Substituted piperazines as central nervous system agents
US5091428A (en) * 1987-04-24 1992-02-25 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US5142052A (en) * 1988-04-22 1992-08-25 Laboratoires Syntex Cationic effect-driven carbinol/amine reaction
US5252736A (en) * 1987-04-24 1993-10-12 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2543139A1 (en) * 1983-03-22 1984-09-28 Cerm Cent Europ Rech Mauvernay (1-ALCOXY 2-AMINO) ETHYL PYRIDINE OR PYRAZINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
EP0120770A1 (en) * 1983-03-22 1984-10-03 Riom Laboratoires- C.E.R.M. "R.L.-Cerm" - (S.A.) 2-Aminoethyl pyridine or pyrazine derivatives, their preparation and pharmaceutical compositions containing them
DE3425477A1 (en) * 1983-07-11 1985-01-31 Malesci S.p.A. Istituto Farmacobiologico, Florenz/Firenze METHOD FOR THE PRODUCTION OF 1-PYRIDYLALKYL-4-ARYLPIPERAZINES USED AS BLOOD PRESSURE-REDUCING COMPOUNDS AND THEIR SEPARATION THEREOF, AND THE STEREOISOMERS OBTAINED THEREFORE
US5010075A (en) * 1987-04-24 1991-04-23 Syntex Pharmaceuticals Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US4935417A (en) * 1987-04-24 1990-06-19 Syntex Pharmaceuticals Ltd. Sustituted imidazolyl-alkyl-piperazine and -diazepine derivatives for treating cerebrovascular disease
US4829065A (en) * 1987-04-24 1989-05-09 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US5043447A (en) * 1987-04-24 1991-08-27 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US5091428A (en) * 1987-04-24 1992-02-25 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US5252736A (en) * 1987-04-24 1993-10-12 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US5142052A (en) * 1988-04-22 1992-08-25 Laboratoires Syntex Cationic effect-driven carbinol/amine reaction
US4973591A (en) * 1988-10-21 1990-11-27 Syntex Pharmaceuticals, Ltd. Parenteral formulations of 1-diphenylmethyl-4-((2-(4-methylphenyl)-5-methyl-1H-imidazol-4-yl)methyl)piperazine
US5063220A (en) * 1988-10-21 1991-11-05 Syntex Pharmaceuticals, Ltd. Parenteral formulations of 1-diphenylmethyl-4-((2-(4-methylphenyl)-5-methyl-1H-imidazol-4-yl)methyl)piperazine
US5089497A (en) * 1990-09-20 1992-02-18 Warner-Lambert Company Substituted piperazines as central nervous system agents

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee