GB1447162A - Triterpene derivatives - Google Patents
Triterpene derivativesInfo
- Publication number
- GB1447162A GB1447162A GB1088174A GB1088174A GB1447162A GB 1447162 A GB1447162 A GB 1447162A GB 1088174 A GB1088174 A GB 1088174A GB 1088174 A GB1088174 A GB 1088174A GB 1447162 A GB1447162 A GB 1447162A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- optionally followed
- glycyrrhetinic
- derivatives
- triterpene derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1447162 Glycyrrhetinic derivatives LANDERLAN SA 12 March 1974 10881/74 Heading C2U The invention comprises compounds of formula (wherein R is H or acyl of at least 2 carbon atoms, and R 1 is C 1-4 alkyl), and the hydrochlorides, hydrobromides and N-(C 1-4 alkyl) quaternary ammonium salts thereof; and their preparation from glycyrrhetinic acid or a 3- acylate thereof by reaction with a 1-alkyl-2- halomethylpyrrolidine to give I as an HCl or HBr salt, optionally followed by desalification with an aqueous or alcoholic alkali, optionally followed by quaternization. The inventive compounds are said to inhibit gastroduodenal ulcers.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1088174A GB1447162A (en) | 1974-03-12 | 1974-03-12 | Triterpene derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1088174A GB1447162A (en) | 1974-03-12 | 1974-03-12 | Triterpene derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1447162A true GB1447162A (en) | 1976-08-25 |
Family
ID=9976047
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1088174A Expired GB1447162A (en) | 1974-03-12 | 1974-03-12 | Triterpene derivatives |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1447162A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007041969A1 (en) * | 2005-10-14 | 2007-04-19 | Tianjin Institute Of Pharmaceutical Research | Glycyrrhetinic acid-30-amide derivatives and the uses thereof |
-
1974
- 1974-03-12 GB GB1088174A patent/GB1447162A/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007041969A1 (en) * | 2005-10-14 | 2007-04-19 | Tianjin Institute Of Pharmaceutical Research | Glycyrrhetinic acid-30-amide derivatives and the uses thereof |
US7790759B2 (en) | 2005-10-14 | 2010-09-07 | Tianjin Institute Of Pharmaceutical Research | Glycyrrhetinic acid-30-amide derivatives and their use |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
414F | Notice of opposition given (sect. 14/1949) | ||
414B | Case decided by the comptroller ** grants allowed (sect. 14/1949) | ||
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |