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GB1399087A - Penicillin compounds - Google Patents

Penicillin compounds

Info

Publication number
GB1399087A
GB1399087A GB2095172A GB2095172A GB1399087A GB 1399087 A GB1399087 A GB 1399087A GB 2095172 A GB2095172 A GB 2095172A GB 2095172 A GB2095172 A GB 2095172A GB 1399087 A GB1399087 A GB 1399087A
Authority
GB
United Kingdom
Prior art keywords
group
syn
acylamidopenam
compounds
organic group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2095172A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Priority to GB2095172A priority Critical patent/GB1399087A/en
Publication of GB1399087A publication Critical patent/GB1399087A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

1399087 Penicillin compounds GLAXO LABORATORIES Ltd 12 May 1972 [14 May 1971] 20951/72 Divided out of 1399086 Heading C2C Novel 6#-acylamidopenam carboxylic acids and salts, esters and 1-sulphoxides thereof, wherein the acylamido group has the structure: in which R is hydrogen or an organic group and R<SP>a</SP> is an etherifying monovalent organic group linked to the oxygen atom through a carbon atom, the said compounds being either in the syn or anti isomeric form as regards the configuration of the group OR<SP>a</SP> with respect to the carboxamido group, or being a mixture of the syn and anti isomers containing at least 75% of one such isomer, are prepared by acylating a 6-amino or 6-isocyanato penam carboxylic acid or salt, ester or 1-oxide thereof, with an acylating agent corresponding to the acid of formula and then recovering the desired acylamidopenam compound, if necessary after separation of the syn and anti isomers.
GB2095172A 1971-05-14 1971-05-14 Penicillin compounds Expired GB1399087A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2095172A GB1399087A (en) 1971-05-14 1971-05-14 Penicillin compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2095172A GB1399087A (en) 1971-05-14 1971-05-14 Penicillin compounds

Publications (1)

Publication Number Publication Date
GB1399087A true GB1399087A (en) 1975-06-25

Family

ID=10154593

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2095172A Expired GB1399087A (en) 1971-05-14 1971-05-14 Penicillin compounds

Country Status (1)

Country Link
GB (1) GB1399087A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0210815A2 (en) * 1985-07-25 1987-02-04 Beecham Group Plc 6-Beta-(alpha-etherified oxyimino)-acylamino penicillanic-acid derivatives, their preparation and use
EP0386940A1 (en) * 1989-03-07 1990-09-12 Beecham Group Plc 6-Beta-(alpha-etherified oxymino)-acyl amino penicillins

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0210815A2 (en) * 1985-07-25 1987-02-04 Beecham Group Plc 6-Beta-(alpha-etherified oxyimino)-acylamino penicillanic-acid derivatives, their preparation and use
EP0210815A3 (en) * 1985-07-25 1988-04-20 Beecham Group Plc 6-beta-(alpha-etherified oxyimino)-acylamino penicillanic-acid derivatives, their preparation and use
US4816452A (en) * 1985-07-25 1989-03-28 Beecham Group P.L.C. Aminothiazole substituted penicillins and antibacterial compositions thereof
EP0386940A1 (en) * 1989-03-07 1990-09-12 Beecham Group Plc 6-Beta-(alpha-etherified oxymino)-acyl amino penicillins

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee