GB1374326A - Amino acids - Google Patents
Amino acidsInfo
- Publication number
- GB1374326A GB1374326A GB5000172A GB5000172A GB1374326A GB 1374326 A GB1374326 A GB 1374326A GB 5000172 A GB5000172 A GB 5000172A GB 5000172 A GB5000172 A GB 5000172A GB 1374326 A GB1374326 A GB 1374326A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- amino acids
- oct
- compounds
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical compound BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 239000012059 conventional drug carrier Substances 0.000 abstract 1
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000012454 non-polar solvent Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Abstract
1374326 Amino acids ROEMMERS SOC ANON INDUSTRIAL COMERCIAL Y FINANOIERA 30 Oct 1972 [28 Oct 1971] 50001/72 Heading C2C The invention comprises compounds having the formula wherein X is =OH- or =N-; R 1 is an aliphatic radical containing at least one alcoholic hydroxyl, carboxylic or amino group; and R 2 and R 3 , which may be the same or different, are a hydrogen, chlorine, bromine or fluorine atom, or a methyl, substituted methyl, -CN, or group. They may be prepared by reacting an acid of the formula with an amine of the formula in a polar or non-polar solvent. The compounds of the invention exhibit anti-inflammatory activity and may be mixed with conventional pharmaceutical carriers and diluents.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AR23873471 | 1971-10-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1374326A true GB1374326A (en) | 1974-11-20 |
Family
ID=3462212
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5000172A Expired GB1374326A (en) | 1971-10-28 | 1972-10-30 | Amino acids |
Country Status (2)
Country | Link |
---|---|
BE (1) | BE790749A (en) |
GB (1) | GB1374326A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5444076A (en) * | 1990-11-26 | 1995-08-22 | Roemmers S.A.I.C.F. | Pharmaceutical preparation for topical application |
US5626872A (en) * | 1992-06-16 | 1997-05-06 | Roemmers S.A.I.C.F. | Pharmaceutical soft capsules containing lysine clonixinate and a process for their preparation |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2262967B1 (en) * | 1974-03-07 | 1977-11-04 | Roemmers Sa Ind Comercial |
-
0
- BE BE790749D patent/BE790749A/en not_active IP Right Cessation
-
1972
- 1972-10-30 GB GB5000172A patent/GB1374326A/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5444076A (en) * | 1990-11-26 | 1995-08-22 | Roemmers S.A.I.C.F. | Pharmaceutical preparation for topical application |
US5626872A (en) * | 1992-06-16 | 1997-05-06 | Roemmers S.A.I.C.F. | Pharmaceutical soft capsules containing lysine clonixinate and a process for their preparation |
Also Published As
Publication number | Publication date |
---|---|
DE2253134A1 (en) | 1973-05-03 |
DE2253134B2 (en) | 1976-02-12 |
BE790749A (en) | 1973-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PE20 | Patent expired after termination of 20 years |