GB1333322A - Process for the preparation of a 7-chloro-benzodiazepine - Google Patents
Process for the preparation of a 7-chloro-benzodiazepineInfo
- Publication number
- GB1333322A GB1333322A GB1333322DA GB1333322A GB 1333322 A GB1333322 A GB 1333322A GB 1333322D A GB1333322D A GB 1333322DA GB 1333322 A GB1333322 A GB 1333322A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzodiazepine
- chloro
- preparation
- march
- ravizza
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YOFINTQUFDULBP-UHFFFAOYSA-N 7-chloro-1h-1,2-benzodiazepine Chemical compound N1N=CC=CC2=CC(Cl)=CC=C21 YOFINTQUFDULBP-UHFFFAOYSA-N 0.000 title 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- SVUOLADPCWQTTE-UHFFFAOYSA-N 1h-1,2-benzodiazepine Chemical compound N1N=CC=CC2=CC=CC=C12 SVUOLADPCWQTTE-UHFFFAOYSA-N 0.000 abstract 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- 229960001760 dimethyl sulfoxide Drugs 0.000 abstract 1
- HDXLZRWEZZFDKA-UHFFFAOYSA-N n-(2-benzoyl-4-chlorophenyl)-2-chloroacetamide Chemical compound ClCC(=O)NC1=CC=C(Cl)C=C1C(=O)C1=CC=CC=C1 HDXLZRWEZZFDKA-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1333322 Benzodiazepine RAVIZZA SA 2 March 1972 [5 March 1971] 6139/71 Heading C2C 7 - Chloro - 5 - phenyl - 2,3 - dihydro - 1H- 1,4 - benzodiazepinone-(2) is prepared by cyclizing 2-chloroacetamido-5-chlorobenzophenone with ammonia in dimethyl sulphoxide. Reference has been directed by the Comptroller to Specification 972,968.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB613971 | 1971-03-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1333322A true GB1333322A (en) | 1973-10-10 |
Family
ID=9809140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1333322D Expired GB1333322A (en) | 1971-03-05 | 1971-03-05 | Process for the preparation of a 7-chloro-benzodiazepine |
Country Status (6)
Country | Link |
---|---|
AT (1) | AT340929B (en) |
CH (1) | CH530406A (en) |
ES (1) | ES396635A1 (en) |
FR (1) | FR2128273B1 (en) |
GB (1) | GB1333322A (en) |
NL (1) | NL7115791A (en) |
-
1971
- 1971-03-05 GB GB1333322D patent/GB1333322A/en not_active Expired
- 1971-07-29 CH CH1118171A patent/CH530406A/en not_active IP Right Cessation
- 1971-10-29 AT AT935171A patent/AT340929B/en not_active IP Right Cessation
- 1971-11-04 ES ES396635A patent/ES396635A1/en not_active Expired
- 1971-11-16 NL NL7115791A patent/NL7115791A/xx unknown
- 1971-11-25 FR FR7142244A patent/FR2128273B1/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2128273B1 (en) | 1974-09-13 |
NL7115791A (en) | 1972-09-07 |
ES396635A1 (en) | 1974-05-16 |
AT340929B (en) | 1978-01-10 |
FR2128273A1 (en) | 1972-10-20 |
CH530406A (en) | 1972-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PLE | Entries relating assignments, transmissions, licences in the register of patents | ||
PCNP | Patent ceased through non-payment of renewal fee |