GB1331826A - Prostaglandin analogues and the preparation thereof - Google Patents
Prostaglandin analogues and the preparation thereofInfo
- Publication number
- GB1331826A GB1331826A GB5654571A GB5654571A GB1331826A GB 1331826 A GB1331826 A GB 1331826A GB 5654571 A GB5654571 A GB 5654571A GB 5654571 A GB5654571 A GB 5654571A GB 1331826 A GB1331826 A GB 1331826A
- Authority
- GB
- United Kingdom
- Prior art keywords
- endo
- hex
- cis
- compounds
- oxobicyclo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
- C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
- C07C35/27—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system containing six carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10333870A | 1970-12-31 | 1970-12-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1331826A true GB1331826A (en) | 1973-09-26 |
Family
ID=22294645
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5654571A Expired GB1331826A (en) | 1970-12-31 | 1971-12-06 | Prostaglandin analogues and the preparation thereof |
Country Status (10)
Country | Link |
---|---|
AU (1) | AU460611B2 (de) |
BE (1) | BE777612A (de) |
CA (1) | CA972356A (de) |
CH (1) | CH605726A5 (de) |
DE (1) | DE2165184A1 (de) |
FR (1) | FR2120163B1 (de) |
GB (1) | GB1331826A (de) |
NL (1) | NL7118204A (de) |
SE (2) | SE397087B (de) |
ZA (1) | ZA718157B (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110790737A (zh) * | 2019-11-07 | 2020-02-14 | 河南中烟工业有限责任公司 | 一种2,3-二氢-3,5-二羟基-6-乙基-4h-吡喃-4-酮的制备方法 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3983163A (en) * | 1973-05-21 | 1976-09-28 | The Upjohn Company | 5-Oxa phenyl- and phenoxy-substituted prostaglandin β, analogs |
US3968144A (en) * | 1973-05-21 | 1976-07-06 | The Upjohn Company | 5-Oxa-11-deoxy phenyl- and phenoxy-substituted prostalandin E1 analogs |
US3966795A (en) * | 1973-05-21 | 1976-06-29 | The Upjohn Company | 5-Oxa-11-deoxyphenyl- and phenoxy-substituted prostaglandin F1.sub.α analogs |
US3864387A (en) * | 1973-05-21 | 1975-02-04 | Upjohn Co | 5-Oxa phenyl-and phenoxy-substituted prostaglandin F{HD 1{301 {0 {B analogs |
US3983158A (en) * | 1974-04-11 | 1976-09-28 | The Upjohn Company | 3-Oxa phenyl-substituted PGA compounds |
US3980694A (en) * | 1974-04-11 | 1976-09-14 | The Upjohn Company | 4-Oxa phenyl-substituted PGA compounds |
US3983157A (en) * | 1974-04-11 | 1976-09-28 | The Upjohn Company | 4-Oxa phenyl-substituted PGF compounds |
-
1971
- 1971-12-02 CA CA129,135A patent/CA972356A/en not_active Expired
- 1971-12-06 ZA ZA718157A patent/ZA718157B/xx unknown
- 1971-12-06 GB GB5654571A patent/GB1331826A/en not_active Expired
- 1971-12-09 AU AU36678/71A patent/AU460611B2/en not_active Expired
- 1971-12-27 SE SE7116625A patent/SE397087B/xx unknown
- 1971-12-29 DE DE19712165184 patent/DE2165184A1/de not_active Withdrawn
- 1971-12-29 CH CH1916371A patent/CH605726A5/xx not_active IP Right Cessation
- 1971-12-30 FR FR7147672A patent/FR2120163B1/fr not_active Expired
- 1971-12-31 NL NL7118204A patent/NL7118204A/xx unknown
- 1971-12-31 BE BE777612A patent/BE777612A/xx not_active IP Right Cessation
-
1975
- 1975-02-17 SE SE7501733A patent/SE7501733L/xx unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110790737A (zh) * | 2019-11-07 | 2020-02-14 | 河南中烟工业有限责任公司 | 一种2,3-二氢-3,5-二羟基-6-乙基-4h-吡喃-4-酮的制备方法 |
CN110790737B (zh) * | 2019-11-07 | 2022-07-22 | 河南中烟工业有限责任公司 | 一种2,3-二氢-3,5-二羟基-6-乙基-4h-吡喃-4-酮的制备方法 |
Also Published As
Publication number | Publication date |
---|---|
ZA718157B (en) | 1972-09-27 |
FR2120163B1 (de) | 1975-10-10 |
SE397087B (sv) | 1977-10-17 |
CA972356A (en) | 1975-08-05 |
FR2120163A1 (de) | 1972-08-11 |
SE7501733L (sv) | 1975-02-17 |
CH605726A5 (de) | 1978-10-13 |
AU460611B2 (en) | 1975-05-01 |
DE2165184A1 (de) | 1972-07-13 |
NL7118204A (de) | 1972-07-04 |
AU3667871A (en) | 1973-06-14 |
BE777612A (fr) | 1972-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |