GB1321692A - Dihydro-3-piperidyl-2 3h-furanone derivatives - Google Patents
Dihydro-3-piperidyl-2 3h-furanone derivativesInfo
- Publication number
- GB1321692A GB1321692A GB1321692DA GB1321692A GB 1321692 A GB1321692 A GB 1321692A GB 1321692D A GB1321692D A GB 1321692DA GB 1321692 A GB1321692 A GB 1321692A
- Authority
- GB
- United Kingdom
- Prior art keywords
- piperidyl
- dihydro
- hydroxy
- acid
- furanone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1321692 Derivatives of 4-hydroxy-1-phenethylpiperidine SANDOZ Ltd 16 June 1970 [8 July 1969 (2) 5 Aug 1969 12 Nov 1969 5 March 1970 21 April 1970 (2)] 60018/72 Divided out of 1321691 Heading C2C The invention comprises compounds of formula and their acid addition salts, and a process for making them by reacting in an inert solvent and in presence of an acid-binding agent 4,5-dihydro- 3-(4-hydroxy-4-piperidyl-2(3H)-furanone with 2-R 1 C 6 H 4 CH 2 CH 2 X; R 1 being H or Cl, and X the acid radical of a reactive ester. Therapeutic compositions having analgesic activity comprise compounds of the above formula, which may be administered in unit doses or in sustained release form.
Applications Claiming Priority (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1040269A CH511885A (en) | 1969-07-08 | 1969-07-08 | Process for the production of new furanone derivatives |
CH1040369A CH511886A (en) | 1969-07-08 | 1969-07-08 | Process for the production of new furanone derivatives |
CH1184369 | 1969-08-05 | ||
CH1681169 | 1969-11-12 | ||
CH1814869A CH518973A (en) | 1969-07-08 | 1969-12-05 | Process for the production of new furanone derivatives |
CH319970 | 1970-03-05 | ||
CH589370 | 1970-04-21 | ||
CH589570 | 1970-04-21 | ||
GB6001872 | 1970-06-16 | ||
GB2923370 | 1970-06-16 | ||
NL7009431A NL7009431A (en) | 1969-07-08 | 1970-06-26 | |
DE19702033852 DE2033852A1 (en) | 1969-07-08 | 1970-07-01 | Process for the preparation of new heterocyclic compounds |
FR7024950A FR2059492B1 (en) | 1969-07-08 | 1970-07-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1321692A true GB1321692A (en) | 1973-06-27 |
Family
ID=27583939
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1321691D Expired GB1321691A (en) | 1969-07-08 | 1970-06-16 | Dihydro-3-piperidyl-2 3h-furanone derivatives |
GB1321692D Expired GB1321692A (en) | 1969-07-08 | 1970-06-16 | Dihydro-3-piperidyl-2 3h-furanone derivatives |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1321691D Expired GB1321691A (en) | 1969-07-08 | 1970-06-16 | Dihydro-3-piperidyl-2 3h-furanone derivatives |
Country Status (7)
Country | Link |
---|---|
AT (3) | AT317882B (en) |
BE (1) | BE753068A (en) |
CH (3) | CH511885A (en) |
DE (1) | DE2033852A1 (en) |
FR (1) | FR2059492B1 (en) |
GB (2) | GB1321691A (en) |
NL (1) | NL7009431A (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2112868A1 (en) * | 1970-03-20 | 1971-10-14 | Sandoz Ag | Process for the preparation of new heterocyclic compounds |
CH530387A (en) * | 1970-07-29 | 1972-11-15 | Sandoz Ag | Process for the production of new Furano derivatives |
US4381890A (en) * | 1980-05-19 | 1983-05-03 | Wallace George A | Incident light filter for cameras |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH497458A (en) * | 1967-04-19 | 1970-10-15 | Sandoz Ag | Process for the preparation of new phenothiazine derivatives |
-
1969
- 1969-07-08 CH CH1040269A patent/CH511885A/en not_active IP Right Cessation
- 1969-07-08 CH CH1040369A patent/CH511886A/en not_active IP Right Cessation
- 1969-12-05 CH CH1814869A patent/CH518973A/en not_active IP Right Cessation
-
1970
- 1970-06-16 GB GB1321691D patent/GB1321691A/en not_active Expired
- 1970-06-16 GB GB1321692D patent/GB1321692A/en not_active Expired
- 1970-06-26 NL NL7009431A patent/NL7009431A/xx unknown
- 1970-07-01 DE DE19702033852 patent/DE2033852A1/en active Pending
- 1970-07-06 BE BE753068D patent/BE753068A/en unknown
- 1970-07-06 FR FR7024950A patent/FR2059492B1/fr not_active Expired
- 1970-07-07 AT AT241472A patent/AT317882B/en not_active IP Right Cessation
- 1970-07-07 AT AT614570A patent/AT312586B/en not_active IP Right Cessation
- 1970-07-07 AT AT241572A patent/AT317883B/en active
Also Published As
Publication number | Publication date |
---|---|
NL7009431A (en) | 1971-01-12 |
BE753068A (en) | 1971-01-06 |
FR2059492A1 (en) | 1971-06-04 |
FR2059492B1 (en) | 1974-06-14 |
AT317882B (en) | 1974-09-25 |
CH511886A (en) | 1971-08-31 |
DE2033852A1 (en) | 1971-01-14 |
GB1321691A (en) | 1973-06-27 |
CH518973A (en) | 1972-02-15 |
AT312586B (en) | 1974-01-10 |
AT317883B (en) | 1974-09-25 |
CH511885A (en) | 1971-08-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
426 | Order made revoking patent and granting patent of addition in lieu thereof (sect. 26(2)/1949) | ||
PLNP | Patent lapsed through nonpayment of renewal fees |