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GB1321692A - Dihydro-3-piperidyl-2 3h-furanone derivatives - Google Patents

Dihydro-3-piperidyl-2 3h-furanone derivatives

Info

Publication number
GB1321692A
GB1321692A GB1321692DA GB1321692A GB 1321692 A GB1321692 A GB 1321692A GB 1321692D A GB1321692D A GB 1321692DA GB 1321692 A GB1321692 A GB 1321692A
Authority
GB
United Kingdom
Prior art keywords
piperidyl
dihydro
hydroxy
acid
furanone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB1321692A publication Critical patent/GB1321692A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1321692 Derivatives of 4-hydroxy-1-phenethylpiperidine SANDOZ Ltd 16 June 1970 [8 July 1969 (2) 5 Aug 1969 12 Nov 1969 5 March 1970 21 April 1970 (2)] 60018/72 Divided out of 1321691 Heading C2C The invention comprises compounds of formula and their acid addition salts, and a process for making them by reacting in an inert solvent and in presence of an acid-binding agent 4,5-dihydro- 3-(4-hydroxy-4-piperidyl-2(3H)-furanone with 2-R 1 C 6 H 4 CH 2 CH 2 X; R 1 being H or Cl, and X the acid radical of a reactive ester. Therapeutic compositions having analgesic activity comprise compounds of the above formula, which may be administered in unit doses or in sustained release form.
GB1321692D 1969-07-08 1970-06-16 Dihydro-3-piperidyl-2 3h-furanone derivatives Expired GB1321692A (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
CH1040269A CH511885A (en) 1969-07-08 1969-07-08 Process for the production of new furanone derivatives
CH1040369A CH511886A (en) 1969-07-08 1969-07-08 Process for the production of new furanone derivatives
CH1184369 1969-08-05
CH1681169 1969-11-12
CH1814869A CH518973A (en) 1969-07-08 1969-12-05 Process for the production of new furanone derivatives
CH319970 1970-03-05
CH589370 1970-04-21
CH589570 1970-04-21
GB6001872 1970-06-16
GB2923370 1970-06-16
NL7009431A NL7009431A (en) 1969-07-08 1970-06-26
DE19702033852 DE2033852A1 (en) 1969-07-08 1970-07-01 Process for the preparation of new heterocyclic compounds
FR7024950A FR2059492B1 (en) 1969-07-08 1970-07-06

Publications (1)

Publication Number Publication Date
GB1321692A true GB1321692A (en) 1973-06-27

Family

ID=27583939

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1321691D Expired GB1321691A (en) 1969-07-08 1970-06-16 Dihydro-3-piperidyl-2 3h-furanone derivatives
GB1321692D Expired GB1321692A (en) 1969-07-08 1970-06-16 Dihydro-3-piperidyl-2 3h-furanone derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB1321691D Expired GB1321691A (en) 1969-07-08 1970-06-16 Dihydro-3-piperidyl-2 3h-furanone derivatives

Country Status (7)

Country Link
AT (3) AT317882B (en)
BE (1) BE753068A (en)
CH (3) CH511885A (en)
DE (1) DE2033852A1 (en)
FR (1) FR2059492B1 (en)
GB (2) GB1321691A (en)
NL (1) NL7009431A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2112868A1 (en) * 1970-03-20 1971-10-14 Sandoz Ag Process for the preparation of new heterocyclic compounds
CH530387A (en) * 1970-07-29 1972-11-15 Sandoz Ag Process for the production of new Furano derivatives
US4381890A (en) * 1980-05-19 1983-05-03 Wallace George A Incident light filter for cameras

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH497458A (en) * 1967-04-19 1970-10-15 Sandoz Ag Process for the preparation of new phenothiazine derivatives

Also Published As

Publication number Publication date
NL7009431A (en) 1971-01-12
BE753068A (en) 1971-01-06
FR2059492A1 (en) 1971-06-04
FR2059492B1 (en) 1974-06-14
AT317882B (en) 1974-09-25
CH511886A (en) 1971-08-31
DE2033852A1 (en) 1971-01-14
GB1321691A (en) 1973-06-27
CH518973A (en) 1972-02-15
AT312586B (en) 1974-01-10
AT317883B (en) 1974-09-25
CH511885A (en) 1971-08-31

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Legal Events

Date Code Title Description
PS Patent sealed
426 Order made revoking patent and granting patent of addition in lieu thereof (sect. 26(2)/1949)
PLNP Patent lapsed through nonpayment of renewal fees