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GB1313164A - Blood plasma substitute - Google Patents

Blood plasma substitute

Info

Publication number
GB1313164A
GB1313164A GB2027970A GB2027970A GB1313164A GB 1313164 A GB1313164 A GB 1313164A GB 2027970 A GB2027970 A GB 2027970A GB 2027970 A GB2027970 A GB 2027970A GB 1313164 A GB1313164 A GB 1313164A
Authority
GB
United Kingdom
Prior art keywords
meq
ions
gelatin
blood plasma
chloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2027970A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KNOX GELATINE Inc
Original Assignee
KNOX GELATINE Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KNOX GELATINE Inc filed Critical KNOX GELATINE Inc
Publication of GB1313164A publication Critical patent/GB1313164A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1313164 Blood plasma substitutes KNOX GELATINE INC 28 April 1970 [28 April 1969] 20279/70 Heading ASB [Also in Division C3] A blood plasma substitute comprises an aqueous solution of: 0.5 to 6% of gelatin or gelatin derived compound; a non-toxic acetate, citrate, gluconate or lactate in an amount capable of generating in vivo 20 to 60 mEq of bicarbonate ions in body fluids for each litre of solution administered; and sodium, potassium and chloride ions in physiological concentration. Modified fluid gelatin, the reaction product of gelatin of average M.W. 15,000-36,000 with succinic anhydride, oxypolygelatin, and polypeptides coupled with diisocyanate are examples of gelatin derived compounds. The blood plasma substitute preferably contains 135-155 mEq sodium ions, 3-5 mEq potassium ions, 90-110 mEq chloride ions, 2-4 mEq magnesium ions and 3-5 mEq calcium ions per litre. An example discloses blood plasma substitutes comprised of one of the above gelatin-derived compounds, sodium chloride, potassium chloride, magnesium chloride, sodium lactate, glucose or fructose (optional) and distilled water.
GB2027970A 1969-04-28 1970-04-28 Blood plasma substitute Expired GB1313164A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81997369A 1969-04-28 1969-04-28

Publications (1)

Publication Number Publication Date
GB1313164A true GB1313164A (en) 1973-04-11

Family

ID=25229569

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2027970A Expired GB1313164A (en) 1969-04-28 1970-04-28 Blood plasma substitute

Country Status (4)

Country Link
DE (1) DE2020453A1 (en)
FR (1) FR2042381B1 (en)
GB (1) GB1313164A (en)
ZA (1) ZA702706B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3138094A1 (en) * 1980-09-25 1982-05-06 Yamanouchi Pharmaceutical Co., Ltd., Tokyo AGENT FOR IMPROVING BLOOD CIRCULATION
US6080538A (en) * 1993-06-04 2000-06-27 Biotime, Inc. Plasma like solution and methods of use
DE102007047040A1 (en) * 2007-10-01 2009-04-16 Fresenius Kabi Deutschland Gmbh Transparent cold gel
WO2011009797A3 (en) * 2009-07-20 2011-08-25 B. Braun Melsungen Ag Plasma-adapted and balanced gelatin solution

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2746109B1 (en) 1996-03-12 1998-04-17 Rhone Poulenc Rorer Sa ENVIRONMENT FOR THE CONSERVATION OF BIOLOGICAL MATERIAL

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE455206A (en) *
GB886553A (en) * 1958-01-22 1962-01-10 Hoechst Ag Substitutes for blood plasma and process for their manufacture

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3138094A1 (en) * 1980-09-25 1982-05-06 Yamanouchi Pharmaceutical Co., Ltd., Tokyo AGENT FOR IMPROVING BLOOD CIRCULATION
US6080538A (en) * 1993-06-04 2000-06-27 Biotime, Inc. Plasma like solution and methods of use
US6387612B1 (en) * 1993-06-04 2002-05-14 Biotime, Inc. Method of preparing a terminally heat sterilized plasma-like solution
US6406839B1 (en) 1993-06-04 2002-06-18 Biotime, Inc. Methods for using a plasma-like solution
US6410218B2 (en) * 1993-06-04 2002-06-25 Biotime, Inc. Plasma-like solution
US6444418B2 (en) * 1993-06-04 2002-09-03 Biotime, Inc. Plasma-like solution
DE102007047040A1 (en) * 2007-10-01 2009-04-16 Fresenius Kabi Deutschland Gmbh Transparent cold gel
US8865397B2 (en) 2007-10-01 2014-10-21 Fresenius Kabi Deutschland Gmbh Method for cooling an organ with a transparent cooling gel
WO2011009797A3 (en) * 2009-07-20 2011-08-25 B. Braun Melsungen Ag Plasma-adapted and balanced gelatin solution
CN102470147A (en) * 2009-07-20 2012-05-23 布朗·B·梅尔松根股份公司 Balanced gelatin solution suitable for plasma

Also Published As

Publication number Publication date
FR2042381B1 (en) 1974-02-01
ZA702706B (en) 1971-12-29
FR2042381A1 (en) 1971-02-12
DE2020453A1 (en) 1970-11-12

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee