GB1241024A - Pharmaceutical tablet base and a process for its manufacture - Google Patents
Pharmaceutical tablet base and a process for its manufactureInfo
- Publication number
- GB1241024A GB1241024A GB5129868A GB5129868A GB1241024A GB 1241024 A GB1241024 A GB 1241024A GB 5129868 A GB5129868 A GB 5129868A GB 5129868 A GB5129868 A GB 5129868A GB 1241024 A GB1241024 A GB 1241024A
- Authority
- GB
- United Kingdom
- Prior art keywords
- spray
- suspension
- drying
- finely divided
- binder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
1,241,024. Tabletting compositions. BOEHRINGER INGELHEIM G.m.b.H. 29 Oct., 1968, No. 51298/68. Heading A5B. A pharmaceutical tablet base is made by spray-drying a suspension of (a) finely divided silica or alumina, (b) a finely divided inert excipient and, (c) an aqueous solution of a water-soluble binder in proportions such that the spray-dried preparation contains the constituents in the proportions by weight of 1-20% of (a), 60-98% of (b) and 1-20% binder. The viscosity of the suspension may be adjusted prior to spray-drying by introducing a gas into and/or foaming the suspension. In making tablets, the base is preferably mixed with an additional material which is the product of spray-drying a suspension of finely divided silica or alumina in a solution of a swellable binder. Suitable binders (for both spray-dried materials) are soluble starch (APS starch) and hydrophilic cellulose derivatives.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5129868A GB1241024A (en) | 1968-10-29 | 1968-10-29 | Pharmaceutical tablet base and a process for its manufacture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5129868A GB1241024A (en) | 1968-10-29 | 1968-10-29 | Pharmaceutical tablet base and a process for its manufacture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1241024A true GB1241024A (en) | 1971-07-28 |
Family
ID=10459453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5129868A Expired GB1241024A (en) | 1968-10-29 | 1968-10-29 | Pharmaceutical tablet base and a process for its manufacture |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1241024A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2531866A1 (en) * | 1982-08-20 | 1984-02-24 | Narcisse Guy | Rapidly disintegrating tablets comprising benzodiazepine type compounds |
| EP1886671A1 (en) * | 2006-08-10 | 2008-02-13 | The Jordanian Pharmaceutical Manufacturing Co. | Starch silica co-precipitate, method for preparing the same and use thereof |
| WO2008086844A2 (en) * | 2007-01-18 | 2008-07-24 | The Jordanian Pharmaceutical Manufacturing Co. | Co-precipitate, method for preparing the same and uses thereof |
| US9891239B2 (en) | 2007-02-23 | 2018-02-13 | Gilead Sciences, Inc. | Modulators of pharmacokinetic properties of therapeutics |
| US10039718B2 (en) | 2008-05-02 | 2018-08-07 | Gilead Sciences, Inc. | Use of solid carrier particles to improve the processability of a pharmaceutical agent |
-
1968
- 1968-10-29 GB GB5129868A patent/GB1241024A/en not_active Expired
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2531866A1 (en) * | 1982-08-20 | 1984-02-24 | Narcisse Guy | Rapidly disintegrating tablets comprising benzodiazepine type compounds |
| EP1886671A1 (en) * | 2006-08-10 | 2008-02-13 | The Jordanian Pharmaceutical Manufacturing Co. | Starch silica co-precipitate, method for preparing the same and use thereof |
| WO2008017335A2 (en) * | 2006-08-10 | 2008-02-14 | The Jordanian Pharmaceutical Manufacturing Co. | Starch silica co-precipitate, method for preparing the same and use thereof |
| WO2008017335A3 (en) * | 2006-08-10 | 2008-03-27 | Jordanian Pharmaceutical Mfg | Starch silica co-precipitate, method for preparing the same and use thereof |
| WO2008086844A2 (en) * | 2007-01-18 | 2008-07-24 | The Jordanian Pharmaceutical Manufacturing Co. | Co-precipitate, method for preparing the same and uses thereof |
| WO2008086844A3 (en) * | 2007-01-18 | 2009-02-26 | Jordanian Pharmaceutical Mfg | Co-precipitate, method for preparing the same and uses thereof |
| US9891239B2 (en) | 2007-02-23 | 2018-02-13 | Gilead Sciences, Inc. | Modulators of pharmacokinetic properties of therapeutics |
| US10039718B2 (en) | 2008-05-02 | 2018-08-07 | Gilead Sciences, Inc. | Use of solid carrier particles to improve the processability of a pharmaceutical agent |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4036948A (en) | L-ascorbic acid tablets | |
| US3079303A (en) | Basic tablet granulation and process of using same | |
| AU611999B2 (en) | Pharmaceutical granulate | |
| GB1235787A (en) | Sustained release pharmaceutical tablets | |
| IL40475A0 (en) | Novel tetrazole derivatives,their preparation and pharmaceutical compositions containing them | |
| IL42781A0 (en) | Derivatives of (4'-(3" -indolyl)piperidino)alkylarylketones,process for preparing them and pharmaceutical compositions | |
| US3116204A (en) | Pharmaceutical compositions and method of preparing the same | |
| GB1439381A (en) | Alkaline earth carbonate products | |
| GB1241024A (en) | Pharmaceutical tablet base and a process for its manufacture | |
| US4800086A (en) | Preparation of ascorbic acid granules | |
| GB1464923A (en) | Compositions burnt refractory shapes and methods of producing the same | |
| KR910011241A (en) | Spray drying to prepare pharmaceutical powder compositions that can be compressed directly into tablets | |
| US3493659A (en) | Compositions and process for the production thereof | |
| AU456547B2 (en) | Chromanone basic ethers, methods for their preparation and compositions containing them | |
| CA941825A (en) | Redispersible hydrophobic starch derivatives and process for their preparation | |
| US3696188A (en) | Laminated tablets | |
| IL39845A0 (en) | Novel quinazolinone derivatives,their preparation and pharmaceutical compositions containing them | |
| EP0063884A1 (en) | Oxazole derivatives, their preparation and use | |
| US3740432A (en) | Vitamin complexes of niacinamide,riboflavin and sodium ascorbate | |
| CA960655A (en) | N(6)-aralkyl adenosine derivatives, process for their preparation and pharmaceutical compositions containing the same | |
| CA1024988A (en) | Derivatives of 4-chloro-5-sulfamoyl-anthranilic acid, their preparation and pharmaceutical compositions comprising them | |
| AU464013B2 (en) | Derivatives of 1,2,3,4-tetrahydropyrimidine processes for their preparation, and compositions incorporation them | |
| GB1257594A (en) | ||
| GB827635A (en) | Vitamin preparations | |
| IL34549A0 (en) | Benzofuran derivatives,process for the preparation thereof and pharmaceutical compositions containing the same |