[go: up one dir, main page]

GB1220896A - Substituted thiazolo-pyrimidines - Google Patents

Substituted thiazolo-pyrimidines

Info

Publication number
GB1220896A
GB1220896A GB4716068A GB4716068A GB1220896A GB 1220896 A GB1220896 A GB 1220896A GB 4716068 A GB4716068 A GB 4716068A GB 4716068 A GB4716068 A GB 4716068A GB 1220896 A GB1220896 A GB 1220896A
Authority
GB
United Kingdom
Prior art keywords
denotes
formula
products
chlorine
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4716068A
Inventor
Robert Everett Manning
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB1220896A publication Critical patent/GB1220896A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/10—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

1,220,896. Sulphur - containing pyrimidine derivatives. SANDOZ Ltd. 4 Oct., 1968 [3 Nov., 1967; 2 July, 1968], No. 47160/68. Heading C2C. [Also in Division A5] The invention comprises thiazolo-pyrimidines of either of the formulµ in which R denotes a hydrogen atom or a phenyl radical, R 1 denotes a hydrogen, chlorine or fluorine atom, an alkoxy group of 1-4 carbon atoms or a phenyl radical, X denotes a hydrogen or chlorine atom or a trifluoromethyl group, A denotes a hydrogen atom, B denotes a hydroxy group, or A and B together denote a C-C bond, provided that, when X denotes chlorine, R 1 denotes chlorine also, and when X denotes a trifluoromethyl radical, R 1 denotes hydrogen. The compounds of the first formula are prepared by reacting a compound of the formula in which X 1 denotes a bromine or chlorine atom, with propylenethiourea of the formula The products of the second formula are prepared by dehydrating the products of the first formula by treatment with a strong mineral acid. The invention extends to the salts of the products with acids and also to the tautomeric equivalents of products of the first formula, these tautomers being assigned the formula Examples are given. The products have medicinal uses (see Division A5).
GB4716068A 1967-11-03 1968-10-04 Substituted thiazolo-pyrimidines Expired GB1220896A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68030767A 1967-11-03 1967-11-03
US74185668A 1968-07-02 1968-07-02

Publications (1)

Publication Number Publication Date
GB1220896A true GB1220896A (en) 1971-01-27

Family

ID=27102429

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4716068A Expired GB1220896A (en) 1967-11-03 1968-10-04 Substituted thiazolo-pyrimidines

Country Status (7)

Country Link
BE (1) BE723289A (en)
CH (2) CH498140A (en)
DE (1) DE1805948A1 (en)
ES (1) ES359831A1 (en)
FR (2) FR1595659A (en)
GB (1) GB1220896A (en)
SE (1) SE352088B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2195426B1 (en) * 1972-08-09 1975-10-17 Lipha

Also Published As

Publication number Publication date
SE352088B (en) 1972-12-18
ES359831A1 (en) 1970-10-01
CH498139A (en) 1970-10-31
DE1805948A1 (en) 1969-06-26
FR1595659A (en) 1970-06-15
BE723289A (en) 1969-04-30
CH498140A (en) 1970-10-31
FR8194M (en) 1970-09-07

Similar Documents

Publication Publication Date Title
GB1132082A (en) The manufacture of pyrimidine derivatives
IE32035L (en) Preparation of substituted vinyl pyrimidines and¹imidazolines
GB1140089A (en) Alkyl substituted phenothiazines
GB1260848A (en) Propanolamine derivatives
GB1287659A (en) Pyrimidinylpyrazole derivatives
GB1304623A (en)
IE34665B1 (en) Isothioureas and their derivatives
GB1220896A (en) Substituted thiazolo-pyrimidines
GB1187680A (en) New Heterocyclic Substituted Piperazines
GB1168391A (en) Substituted Uracils
GB1226250A (en)
GB1256723A (en)
GB1377308A (en) Pyrimidones
GB1174349A (en) Novel 2-Anilinomethylimidazoline Derivatives and process for the preparation thereof
GB1050554A (en)
GB1253368A (en) Benzodiazepine derivatives and process for preparing them
GB1299421A (en) 3-substituted amino-6-hydrazino-pyridazines
GB845823A (en) Stabilised compositions comprising therapeutic imine derivatives and the preparation thereof
GB1223032A (en) Benzodiazepine derivatives
GB1499286A (en) Imidazolidine-dione derivatives and their use as plant-growth regulators
GB1265744A (en)
GB1265866A (en)
GB1410303A (en) Piperazinyl-butanol derivatives
GB1058403A (en) Improvements in or relating to novel 4-aza-thiaxanthene derivatives
GB1201269A (en) 2-substituted-4(5)-nitroimidazoles