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GB1185283A - Copolymers and process for their manufacture - Google Patents

Copolymers and process for their manufacture

Info

Publication number
GB1185283A
GB1185283A GB947868A GB947868A GB1185283A GB 1185283 A GB1185283 A GB 1185283A GB 947868 A GB947868 A GB 947868A GB 947868 A GB947868 A GB 947868A GB 1185283 A GB1185283 A GB 1185283A
Authority
GB
United Kingdom
Prior art keywords
component
attached
amino
coating
blood vessels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB947868A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
Original Assignee
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba AG filed Critical Ciba AG
Publication of GB1185283A publication Critical patent/GB1185283A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/62—Monocarboxylic acids having ten or more carbon atoms; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

1,185,283. Artificial blood vessels. CIBA Ltd. 27 Feb., 1968 [1 March, 1967], No. 9478/68. Heading A5R. [Also in Divisions C3, D1 and D2] Artificial blood vessels are provided with antithrombogenic coatings by coating the inner surface of the blood vessel with a solution in an organic solvent of an amphoteric copolymer, allowing the solvent to evaporate, and then bringing the coating into prolonged contact with an aqueous solution of heparin, said amphoteric copolymer being the product obtained by copolymerising (a) at least one amino-ester or amino-amide monomer of the formula in which A is a C 2 -C 6 hydrocarbon group and the hetero atoms attached thereto are not attached to the same C atom of A, R 1 and R 2 are unsubstituted or substituted C 1 -C 6 hydrocarbon residues, or together with the attached N atom form a heterocyclic ring, and n and p each is 1 or 2, (b) at least one copolymerisable ethylenically unsaturated acid and (c) at least one water-insoluble, neutral copolymerisable monomer, in proportions (referred to the total weight of the monomers) of 15-30% component (a) the quantity of component (b) needed to neutralise component (a) within the limits of +15 stoichiometric equivalents %, and component (c) to a total of 100%.
GB947868A 1967-03-01 1968-02-27 Copolymers and process for their manufacture Expired GB1185283A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH297767A CH479636A (en) 1967-03-01 1967-03-01 Process for the production of copolymers

Publications (1)

Publication Number Publication Date
GB1185283A true GB1185283A (en) 1970-03-25

Family

ID=4245885

Family Applications (1)

Application Number Title Priority Date Filing Date
GB947868A Expired GB1185283A (en) 1967-03-01 1968-02-27 Copolymers and process for their manufacture

Country Status (6)

Country Link
BE (1) BE711489A (en)
CH (1) CH479636A (en)
DE (1) DE1720439A1 (en)
FR (1) FR1582824A (en)
GB (1) GB1185283A (en)
NL (1) NL6802886A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2452585A1 (en) * 1974-11-06 1976-05-13 Basf Ag PROCESS FOR THE PRODUCTION OF SHEAR-STABLE AQUATIC COPOLYMERISATE DISPERSIONS
US4314800A (en) 1980-04-11 1982-02-09 Rohm Gmbh Method for treating pelts and leather
DE3800199A1 (en) * 1988-01-07 1989-07-20 Sandoz Ag VINYL POLYMERS WITH SIDE CHAINS
EP0331528A1 (en) * 1988-03-03 1989-09-06 Sumitomo Chemical Company, Limited Antimicrobial ethylene copolymers and compositions thereof
AU595901B2 (en) * 1986-07-23 1990-04-12 Chemische Fabrik Stockhausen Gmbh The use of amphoteric water soluble polymers as grinding agents and/or dispersing agents
US4950412A (en) * 1985-01-15 1990-08-21 Lever Brothers Company Fabric conditioning composition
US4964873A (en) * 1985-01-15 1990-10-23 Lever Brothers Company Fabric conditioning method
EP0947205A2 (en) * 1998-04-03 1999-10-06 Medtronic Inc. Method for making biocompatible medical article

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2452585A1 (en) * 1974-11-06 1976-05-13 Basf Ag PROCESS FOR THE PRODUCTION OF SHEAR-STABLE AQUATIC COPOLYMERISATE DISPERSIONS
US4314800A (en) 1980-04-11 1982-02-09 Rohm Gmbh Method for treating pelts and leather
US4950412A (en) * 1985-01-15 1990-08-21 Lever Brothers Company Fabric conditioning composition
US4964873A (en) * 1985-01-15 1990-10-23 Lever Brothers Company Fabric conditioning method
AU595901B2 (en) * 1986-07-23 1990-04-12 Chemische Fabrik Stockhausen Gmbh The use of amphoteric water soluble polymers as grinding agents and/or dispersing agents
DE3800199A1 (en) * 1988-01-07 1989-07-20 Sandoz Ag VINYL POLYMERS WITH SIDE CHAINS
EP0331528A1 (en) * 1988-03-03 1989-09-06 Sumitomo Chemical Company, Limited Antimicrobial ethylene copolymers and compositions thereof
US5208016A (en) * 1988-03-03 1993-05-04 Sumitomo Chemical Co., Ltd. Antimicrobial substance and antimicrobial resin composition containing ethylene copolymer
EP0947205A2 (en) * 1998-04-03 1999-10-06 Medtronic Inc. Method for making biocompatible medical article
EP0947205A3 (en) * 1998-04-03 2001-01-17 Medtronic Inc. Method for making biocompatible medical article

Also Published As

Publication number Publication date
CH479636A (en) 1969-10-15
BE711489A (en) 1968-08-29
NL6802886A (en) 1968-09-02
DE1720439A1 (en) 1971-07-08
FR1582824A (en) 1969-10-10

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees