GB1178984A - Improvements in or relating to Hepatic Medicines - Google Patents

Improvements in or relating to Hepatic Medicines

Info

Publication number: GB1178984A
Authority: GB; United Kingdom
Prior art keywords: hepatic; medicines; june; relating; mixture
Prior art date: 1966-06-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

GB28880/67A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bracco SpA

Original Assignee

Bracco SpA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1966-06-23

Filing date

1967-06-22

Publication date

1970-01-28

1967-06-22 Application filed by Bracco SpA filed Critical Bracco SpA

1970-01-28 Publication of GB1178984A publication Critical patent/GB1178984A/en

Status Expired legal-status Critical Current

Links

229940079593 drug Drugs 0.000 title abstract 2
239000003814 drug Substances 0.000 title abstract 2
230000002440 hepatic effect Effects 0.000 title abstract 2
239000000203 mixture Substances 0.000 abstract 3
YOZNUFWCRFCGIH-BYFNXCQMSA-L hydroxocobalamin Chemical compound O[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O YOZNUFWCRFCGIH-BYFNXCQMSA-L 0.000 abstract 2
UGQMRVRMYYASKQ-DEGSGYPDSA-N 9-[(2s,3s,4r,5s)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purin-6-one Chemical compound O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(NC=NC2=O)=C2N=C1 UGQMRVRMYYASKQ-DEGSGYPDSA-N 0.000 abstract 1
GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 abstract 1
229930024421 Adenine Natural products 0.000 abstract 1
DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 abstract 1
229960000643 adenine Drugs 0.000 abstract 1
AGVAZMGAQJOSFJ-WZHZPDAFSA-M cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].N#[C-].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(O)(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O AGVAZMGAQJOSFJ-WZHZPDAFSA-M 0.000 abstract 1
235000000639 cyanocobalamin Nutrition 0.000 abstract 1
239000011666 cyanocobalamin Substances 0.000 abstract 1
RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 abstract 1
VVIAGPKUTFNRDU-ABLWVSNPSA-N folinic acid Chemical compound C1NC=2NC(N)=NC(=O)C=2N(C=O)C1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 VVIAGPKUTFNRDU-ABLWVSNPSA-N 0.000 abstract 1
235000004867 hydroxocobalamin Nutrition 0.000 abstract 1
239000011704 hydroxocobalamin Substances 0.000 abstract 1
229960001103 hydroxocobalamin Drugs 0.000 abstract 1
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1
208000019423 liver disease Diseases 0.000 abstract 1
FFEARJCKVFRZRR-UHFFFAOYSA-N methionine Chemical compound CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

GB28880/67A 1966-06-23 1967-06-22 Improvements in or relating to Hepatic Medicines Expired GB1178984A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH913566		1966-06-23

Publications (1)

Publication Number	Publication Date
GB1178984A true GB1178984A (en)	1970-01-28

Family

ID=4348691

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GB28880/67A Expired GB1178984A (en)	1966-06-23	1967-06-22	Improvements in or relating to Hepatic Medicines

Country Status (4)

Country	Link
BE (1)	BE700365A (zh)
DE (1)	DE1670234A1 (zh)
FR (1)	FR7028M (zh)
GB (1)	GB1178984A (zh)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6787527B1 (en) *	1994-11-10	2004-09-07	Duke University	Methods of preventing and treating HIV infection
EP1621202A1 (en) *	2003-05-07	2006-02-01	Eisai Co., Ltd.	Freeze-dried preparation containing methylcobalamin and process for producing the same

1967
- 1967-05-31 FR FR108516A patent/FR7028M/fr not_active Expired
- 1967-06-03 DE DE19671670234 patent/DE1670234A1/de active Pending
- 1967-06-22 BE BE700365D patent/BE700365A/xx unknown
- 1967-06-22 GB GB28880/67A patent/GB1178984A/en not_active Expired

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6787527B1 (en) *	1994-11-10	2004-09-07	Duke University	Methods of preventing and treating HIV infection
EP1621202A1 (en) *	2003-05-07	2006-02-01	Eisai Co., Ltd.	Freeze-dried preparation containing methylcobalamin and process for producing the same
EP1621202A4 (en) *	2003-05-07	2007-10-31	Eisai R&D Man Co Ltd	LYOPHILIZED PREPARATION CONTAINING METHYLCOBALAMINE AND PROCESS FOR PRODUCING THE PREPARATION

Also Published As

Publication number	Publication date
DE1670234A1 (de)	1971-01-07
FR7028M (zh)	1969-06-09
BE700365A (zh)	1967-12-22

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