GB1175482A - Reduction of Corticosteroid Side Effects - Google Patents
Reduction of Corticosteroid Side EffectsInfo
- Publication number
- GB1175482A GB1175482A GB2078/68A GB207868A GB1175482A GB 1175482 A GB1175482 A GB 1175482A GB 2078/68 A GB2078/68 A GB 2078/68A GB 207868 A GB207868 A GB 207868A GB 1175482 A GB1175482 A GB 1175482A
- Authority
- GB
- United Kingdom
- Prior art keywords
- corticosteroid
- side effects
- compositions
- pyridyl
- cortisone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
1,175,482. Corticosteroid compositions. UNIMED Inc. 15 Jan., 1968 [9 March, 1967], No. 2078/68. Heading A5B. Corticosteroid compositions with reduced corticosteroid side effects comprise a corticosteroid and at least one compound selected from beta-(2- or 4- pyridyl) alkyl alkylamines and dialkylamines; 1-(2<SP>1</SP>- or 41-pyridyl)-2, 3- cis- or trans-dicarboxylic acid cyclobutanes; alphapicolinic acid dialkylamides; and non- toxic acid addition salts thereof. Examples of anti-inflammatory corticosteroids include cortisone, cortisone phosphate, hydrocortisone and the acetate and 21-sodium succinate thereof, prednisone, dexamethasone and the sodium phosphate salt thereof, ACTH, corticosterone, 11-dehydrocorticosterone, 11-desoxycorticosterone and aldosterone. Suitable salts include the hydrochloride, sulphate, tartrate, fumarate and gluconate. The compositions may be administered orally, parenterally or topically in the form of tablets, ampoules, drops, suspensions or ointments. Corticosteroid side effects are reduced by administering to a non-human animal simultaneously with, before or after administration of the corticosteroid at least one of the above-mentioned compounds.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62179167A | 1967-03-09 | 1967-03-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1175482A true GB1175482A (en) | 1969-12-23 |
Family
ID=24491653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2078/68A Expired GB1175482A (en) | 1967-03-09 | 1968-01-15 | Reduction of Corticosteroid Side Effects |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3474168A (en) |
| BE (1) | BE710504A (en) |
| DE (1) | DE1667925A1 (en) |
| FR (1) | FR7356M (en) |
| GB (1) | GB1175482A (en) |
| IE (1) | IE31885B1 (en) |
| IL (1) | IL29319A (en) |
| NL (1) | NL6801136A (en) |
| SE (1) | SE347874B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4353896A (en) * | 1981-06-08 | 1982-10-12 | Levy Michael A | Penetrating topical medicament |
| US4945089A (en) * | 1987-12-29 | 1990-07-31 | Alcon Laboratories, Inc. | Use of tetrahydrocortexolone to prevent elevations in intraocular pressure caused by corticosteroids |
| US5358943A (en) * | 1987-12-29 | 1994-10-25 | Clark Abbot F | Use of tetrahydrocortisol to prevent elevations in intraocular pressure caused by corticosteroids |
| US20060074063A1 (en) * | 1995-12-29 | 2006-04-06 | Fernandez-Pol Jose A | Pharmacological agent and method of treatment |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2794763A (en) * | 1955-01-27 | 1957-06-04 | Pfizer & Co C | Pressor amines |
| US3105010A (en) * | 1959-06-19 | 1963-09-24 | Schering Corp | Steroid-amino acid compositions for preventing negative nitrogen balance |
| US3415833A (en) * | 1964-04-16 | 1968-12-10 | Unimed Inc | Pyridyl-dicarboxylic acid cyclobutane derivatives |
| US3984304A (en) * | 1974-11-11 | 1976-10-05 | Ppg Industries, Inc. | Electrode unit |
-
1967
- 1967-03-09 US US621791A patent/US3474168A/en not_active Expired - Lifetime
-
1968
- 1968-01-15 GB GB2078/68A patent/GB1175482A/en not_active Expired
- 1968-01-15 DE DE19681667925 patent/DE1667925A1/en active Pending
- 1968-01-17 IL IL29319A patent/IL29319A/en unknown
- 1968-01-19 SE SE00763/68A patent/SE347874B/xx unknown
- 1968-01-23 IE IE93/68A patent/IE31885B1/en unknown
- 1968-01-25 NL NL6801136A patent/NL6801136A/xx unknown
- 1968-02-08 BE BE710504D patent/BE710504A/xx unknown
- 1968-02-20 FR FR140522A patent/FR7356M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3474168A (en) | 1969-10-21 |
| NL6801136A (en) | 1968-09-10 |
| DE1667925A1 (en) | 1971-07-22 |
| IE31885B1 (en) | 1973-02-07 |
| IL29319A (en) | 1971-11-29 |
| SE347874B (en) | 1972-08-21 |
| FR7356M (en) | 1969-10-20 |
| BE710504A (en) | 1968-06-17 |
| IE31885L (en) | 1968-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |