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GB1166123A - Process for the Preparation of 1,2,3,4,5,6-Hexahydro-2,5-Benzodiazocine Derivatives - Google Patents

Process for the Preparation of 1,2,3,4,5,6-Hexahydro-2,5-Benzodiazocine Derivatives

Info

Publication number
GB1166123A
GB1166123A GB44711/66A GB4471166A GB1166123A GB 1166123 A GB1166123 A GB 1166123A GB 44711/66 A GB44711/66 A GB 44711/66A GB 4471166 A GB4471166 A GB 4471166A GB 1166123 A GB1166123 A GB 1166123A
Authority
GB
United Kingdom
Prior art keywords
hexahydro
substituted
general formula
benzodiazocine
oct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB44711/66A
Inventor
William Joseph Houlihan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB1166123A publication Critical patent/GB1166123A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D245/00Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
    • C07D245/04Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D245/06Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,166,123. Benzodiazocine derivatives. SANDOZ Ltd. 6 Oct., 1966 [18 Oct., 1965], No. 44711/66. Heading C2C. 1 - Substituted - 1,2,3,4,5,6 - hexahydro - 2,5- benzodiazocines of the general formula wherein R is a phenyl or p-chlorophenyl radical, and acid addition salts thereof are prepared by reduction of a 9b - substituted - 1,2,3,9btetrahydro - 5H - imidazo[2,1 - a]isoindol - 5- one of the general formula with an aluminium hydride, followed by optional conversion to an acid addition salt of the product. Pharmaceutical compositions comprising a 1- substituted - 1,2,3,4,5,6 - hexahydro - 2,5- benzodiazocine of the first general formula above, as active ingredient, in addition to a physiologically acceptable, inert carrier, are central nervous stimulants and appetite depressants and may be administered orally or parenterally. Reference has been directed by the Comptroller to Specification 1,059,174.
GB44711/66A 1965-10-18 1966-10-06 Process for the Preparation of 1,2,3,4,5,6-Hexahydro-2,5-Benzodiazocine Derivatives Expired GB1166123A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49746765A 1965-10-18 1965-10-18

Publications (1)

Publication Number Publication Date
GB1166123A true GB1166123A (en) 1969-10-08

Family

ID=23977003

Family Applications (1)

Application Number Title Priority Date Filing Date
GB44711/66A Expired GB1166123A (en) 1965-10-18 1966-10-06 Process for the Preparation of 1,2,3,4,5,6-Hexahydro-2,5-Benzodiazocine Derivatives

Country Status (8)

Country Link
AT (1) AT265287B (en)
BE (1) BE688325A (en)
CH (1) CH476741A (en)
DE (1) DE1620413A1 (en)
ES (1) ES332284A1 (en)
FR (2) FR1502948A (en)
GB (1) GB1166123A (en)
NL (1) NL6614399A (en)

Also Published As

Publication number Publication date
DE1620413A1 (en) 1970-02-19
NL6614399A (en) 1967-04-19
FR1502948A (en) 1967-11-24
FR6151M (en) 1968-07-01
AT265287B (en) 1968-10-10
ES332284A1 (en) 1967-12-01
BE688325A (en) 1967-04-17
CH476741A (en) 1969-08-15

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Legal Events

Date Code Title Description
416 Proceeding under section 16 patents act 1949
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees