GB1109179A - Improvements relating to typhoid and paratyphoid vaccines - Google Patents
Improvements relating to typhoid and paratyphoid vaccinesInfo
- Publication number
- GB1109179A GB1109179A GB39819/64A GB3981964A GB1109179A GB 1109179 A GB1109179 A GB 1109179A GB 39819/64 A GB39819/64 A GB 39819/64A GB 3981964 A GB3981964 A GB 3981964A GB 1109179 A GB1109179 A GB 1109179A
- Authority
- GB
- United Kingdom
- Prior art keywords
- typhoid
- improvements relating
- flagella
- flagellar
- strain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 208000037386 Typhoid Diseases 0.000 title 1
- 201000008297 typhoid fever Diseases 0.000 title 1
- 210000003495 flagella Anatomy 0.000 abstract 2
- 101710194807 Protective antigen Proteins 0.000 abstract 1
- 241000531795 Salmonella enterica subsp. enterica serovar Paratyphi A Species 0.000 abstract 1
- 241000577483 Salmonella enterica subsp. enterica serovar Paratyphi B Species 0.000 abstract 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0275—Salmonella
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Vaccines comprise as protective antigen a killed, stable, non-motile strain of Salmonella typhi or S. paratyphi A or B which is devoid of flagella capable of producing the corresponding TH, TA or TB antibodies. An independent antigenic marker, e.g. a rare flagellar antigen such as S. aderike, S. weslaco, S. guinea or S. irigny, may be included. The non-flagellar strain may be a natural or artificial mutant or a phenotypical organism produced by mechanical removal or inhibition of the growth of the flagella.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB39819/64A GB1109179A (en) | 1964-09-30 | 1964-09-30 | Improvements relating to typhoid and paratyphoid vaccines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB39819/64A GB1109179A (en) | 1964-09-30 | 1964-09-30 | Improvements relating to typhoid and paratyphoid vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1109179A true GB1109179A (en) | 1968-04-10 |
Family
ID=10411678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB39819/64A Expired GB1109179A (en) | 1964-09-30 | 1964-09-30 | Improvements relating to typhoid and paratyphoid vaccines |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1109179A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1112747A1 (en) * | 1999-12-28 | 2001-07-04 | Akzo Nobel N.V. | Salmonella vaccine not inducing antibodies against flagellin or flagella |
| US20140186398A1 (en) * | 2011-07-18 | 2014-07-03 | Icahn School Of Medicine At Mount Sinai | BACTERIAL RNAs AS VACCINE ADJUVANTS |
-
1964
- 1964-09-30 GB GB39819/64A patent/GB1109179A/en not_active Expired
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1112747A1 (en) * | 1999-12-28 | 2001-07-04 | Akzo Nobel N.V. | Salmonella vaccine not inducing antibodies against flagellin or flagella |
| AU783508B2 (en) * | 1999-12-28 | 2005-11-03 | Intervet International B.V. | Salmonella vaccine |
| US20140186398A1 (en) * | 2011-07-18 | 2014-07-03 | Icahn School Of Medicine At Mount Sinai | BACTERIAL RNAs AS VACCINE ADJUVANTS |
| US9844592B2 (en) * | 2011-07-18 | 2017-12-19 | Icahn School Of Medicine At Mount Sinai | Bacterial RNAs as vaccine adjuvants |
| US10588964B2 (en) | 2011-07-18 | 2020-03-17 | Cornell University | Bacterial RNAs as vaccine adjuvants |
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