GB1100643A - ª-alkyl thyronines and method of preparing these compounds - Google Patents
ª-alkyl thyronines and method of preparing these compoundsInfo
- Publication number
- GB1100643A GB1100643A GB13872/65A GB1387265A GB1100643A GB 1100643 A GB1100643 A GB 1100643A GB 13872/65 A GB13872/65 A GB 13872/65A GB 1387265 A GB1387265 A GB 1387265A GB 1100643 A GB1100643 A GB 1100643A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- general formula
- methylhydantoin
- diiodo
- acylated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 5
- VMAQYKGITHDWKL-UHFFFAOYSA-N 5-Methyl hydantoin Natural products CC1NC(=O)NC1=O VMAQYKGITHDWKL-UHFFFAOYSA-N 0.000 abstract 3
- 239000002904 solvent Substances 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 239000012670 alkaline solution Substances 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000000664 diazo group Chemical group [N-]=[N+]=[*] 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 abstract 1
- 229940091173 hydantoin Drugs 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000026045 iodination Effects 0.000 abstract 1
- 238000006192 iodination reaction Methods 0.000 abstract 1
- 125000002346 iodo group Chemical group I* 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000010792 warming Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
- C07D233/78—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEC0032613 | 1964-04-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1100643A true GB1100643A (en) | 1968-01-24 |
Family
ID=7020410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB13872/65A Expired GB1100643A (en) | 1964-04-10 | 1965-04-01 | ª-alkyl thyronines and method of preparing these compounds |
Country Status (13)
| Country | Link |
|---|---|
| AT (3) | AT268553B (fr) |
| BE (1) | BE662271A (fr) |
| BR (1) | BR6568876D0 (fr) |
| CH (1) | CH469664A (fr) |
| DE (1) | DE1793776A1 (fr) |
| DK (1) | DK123229B (fr) |
| ES (1) | ES311669A1 (fr) |
| FI (1) | FI43439C (fr) |
| FR (1) | FR1587317A (fr) |
| GB (1) | GB1100643A (fr) |
| NL (1) | NL142402B (fr) |
| OA (1) | OA01689A (fr) |
| SE (1) | SE332994B (fr) |
-
1965
- 1965-03-08 AT AT372066A patent/AT268553B/de active
- 1965-03-08 AT AT371966A patent/AT268552B/de active
- 1965-03-08 AT AT203465A patent/AT268547B/de active
- 1965-03-11 DE DE19651793776 patent/DE1793776A1/de active Pending
- 1965-03-15 NL NL656503266A patent/NL142402B/xx unknown
- 1965-04-01 GB GB13872/65A patent/GB1100643A/en not_active Expired
- 1965-04-05 FI FI650814A patent/FI43439C/fi active
- 1965-04-07 CH CH480865A patent/CH469664A/de unknown
- 1965-04-08 BE BE662271A patent/BE662271A/xx unknown
- 1965-04-09 OA OA51586A patent/OA01689A/fr unknown
- 1965-04-09 FR FR1587317D patent/FR1587317A/fr not_active Expired
- 1965-04-09 SE SE04627/65A patent/SE332994B/xx unknown
- 1965-04-09 BR BR168876/65A patent/BR6568876D0/pt unknown
- 1965-04-09 DK DK183165AA patent/DK123229B/da unknown
- 1965-04-09 ES ES0311669A patent/ES311669A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BR6568876D0 (pt) | 1973-08-07 |
| DK123229B (da) | 1972-05-29 |
| SE332994B (fr) | 1971-03-01 |
| FI43439C (fi) | 1971-04-13 |
| NL142402B (nl) | 1974-06-17 |
| AT268553B (de) | 1969-02-10 |
| FI43439B (fr) | 1970-12-31 |
| FR1587317A (fr) | 1970-03-20 |
| AT268547B (de) | 1969-02-10 |
| NL6503266A (fr) | 1965-10-11 |
| CH469664A (de) | 1969-03-15 |
| ES311669A1 (es) | 1965-07-01 |
| OA01689A (fr) | 1969-12-15 |
| AT268552B (de) | 1969-02-10 |
| BE662271A (fr) | 1965-10-08 |
| DE1793776A1 (de) | 1974-08-29 |
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