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GB1046167A - Novel amine salts - Google Patents

Novel amine salts

Info

Publication number
GB1046167A
GB1046167A GB34212/65A GB3421265A GB1046167A GB 1046167 A GB1046167 A GB 1046167A GB 34212/65 A GB34212/65 A GB 34212/65A GB 3421265 A GB3421265 A GB 3421265A GB 1046167 A GB1046167 A GB 1046167A
Authority
GB
United Kingdom
Prior art keywords
amine salts
salt
novel amine
phenyltoloxamine
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB34212/65A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB1046167A publication Critical patent/GB1046167A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/105Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/105Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic
    • C07C65/11Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic with carboxyl groups on a condensed ring system containing two rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Phenyltoloxamine pamoate and metal salts thereof are prepared by reacting phenyltoloxamine or a salt thereof with pamoic acid or a salt thereof, optionally followed by conversion to a metal salt. The compounds of the invention may be administered orally in the form of pharmaceutical preparations containing them together with a carrier.
GB34212/65A 1964-08-17 1965-08-10 Novel amine salts Expired GB1046167A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US390204A US3372177A (en) 1964-08-17 1964-08-17 Phenyltoloxamine aluminum pamoate

Publications (1)

Publication Number Publication Date
GB1046167A true GB1046167A (en) 1966-10-19

Family

ID=23541541

Family Applications (1)

Application Number Title Priority Date Filing Date
GB34212/65A Expired GB1046167A (en) 1964-08-17 1965-08-10 Novel amine salts

Country Status (13)

Country Link
US (1) US3372177A (en)
BE (1) BE668227A (en)
BR (1) BR6572186D0 (en)
CH (1) CH464232A (en)
DE (1) DE1493489A1 (en)
DK (1) DK120957B (en)
ES (1) ES316439A1 (en)
FI (1) FI44623C (en)
FR (2) FR4762M (en)
GB (1) GB1046167A (en)
IL (1) IL24076A (en)
NL (1) NL6510752A (en)
SE (1) SE334161B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3491135A (en) * 1969-03-03 1970-01-20 American Cyanamid Co Pamoates of (3-cyclohexyl-3-hydroxy-3-phenylpropyl) triethylammonium having unobjectionable flavors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2731470A (en) * 1956-01-17 N-pyrtoylmethyl
US2578537A (en) * 1949-12-08 1951-12-11 Bristol Lab Inc Amine salt of penicillin
US2703324A (en) * 1950-08-30 1955-03-01 Bristol Lab Inc Basic ethers of aralkyl phenols and salts thereof
US2641610A (en) * 1950-10-27 1953-06-09 May & Baker Ltd Quaternary ammonium salts
NL83750C (en) * 1951-02-05
US3225091A (en) * 1962-02-01 1965-12-21 Lilly Co Eli Anticholinergic substituted butyramides
BE633486A (en) * 1962-06-18
US3261868A (en) * 1963-03-14 1966-07-19 Upjohn Co Aminoalkoxy-hydroxyacetophenones
US3173835A (en) * 1963-03-19 1965-03-16 Endo Lab Composition of n-acetyl-p-aminophenol and phenyltoloxamine for analgesia

Also Published As

Publication number Publication date
FR4762M (en) 1967-01-16
NL6510752A (en) 1966-02-18
BR6572186D0 (en) 1973-08-14
CH464232A (en) 1968-10-31
IL24076A (en) 1969-02-27
BE668227A (en) 1966-02-14
FI44623B (en) 1971-08-31
DK120957B (en) 1971-08-09
SE334161B (en) 1971-04-19
FI44623C (en) 1971-12-10
DE1493489A1 (en) 1969-04-24
ES316439A1 (en) 1966-04-01
US3372177A (en) 1968-03-05
FR1449108A (en) 1966-03-18

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