GB0720891D0 - Chemical process - Google Patents
Chemical processInfo
- Publication number
- GB0720891D0 GB0720891D0 GBGB0720891.1A GB0720891A GB0720891D0 GB 0720891 D0 GB0720891 D0 GB 0720891D0 GB 0720891 A GB0720891 A GB 0720891A GB 0720891 D0 GB0720891 D0 GB 0720891D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- chemical process
- chemical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000001311 chemical methods and process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0720891A GB2453982B (en) | 2007-10-24 | 2007-10-24 | Chemical process for the preparation of Medetomidine |
ARP080104589A AR068952A1 (en) | 2007-10-24 | 2008-10-22 | PROCEDURE FOR THE PREPARATION OF MEDETOMIDINE |
UY31415A UY31415A1 (en) | 2007-10-24 | 2008-10-22 | PROCEDURE FOR THE PREPARATION OF MEDETOMIDINE |
PE2008001820A PE20091088A1 (en) | 2007-10-24 | 2008-10-23 | PROCESS FOR THE PREPARATION OF MEDETOMIDINE |
CL2008003185A CL2008003185A1 (en) | 2007-10-24 | 2008-10-24 | Procedure for the preparation of medetomidine that considers the coupling between a silyimidazole and a derivative of benzyl alcohol. |
PCT/GB2008/003613 WO2009053709A1 (en) | 2007-10-24 | 2008-10-24 | Process for the preparation of medetomidine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0720891A GB2453982B (en) | 2007-10-24 | 2007-10-24 | Chemical process for the preparation of Medetomidine |
Publications (3)
Publication Number | Publication Date |
---|---|
GB0720891D0 true GB0720891D0 (en) | 2007-12-05 |
GB2453982A GB2453982A (en) | 2009-04-29 |
GB2453982B GB2453982B (en) | 2009-09-16 |
Family
ID=38829878
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB0720891A Expired - Fee Related GB2453982B (en) | 2007-10-24 | 2007-10-24 | Chemical process for the preparation of Medetomidine |
Country Status (6)
Country | Link |
---|---|
AR (1) | AR068952A1 (en) |
CL (1) | CL2008003185A1 (en) |
GB (1) | GB2453982B (en) |
PE (1) | PE20091088A1 (en) |
UY (1) | UY31415A1 (en) |
WO (1) | WO2009053709A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114671811A (en) * | 2022-04-14 | 2022-06-28 | 南京正科医药股份有限公司 | Racemization recovery method of dexmedetomidine resolution byproduct |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101921234B (en) * | 2009-06-12 | 2012-05-30 | 中国中化股份有限公司 | Method for preparing medetomidine |
WO2011070069A1 (en) | 2009-12-09 | 2011-06-16 | I-Tech Ab | Process for preparation of medetomidine |
ES2665093T3 (en) * | 2011-07-22 | 2018-04-24 | Cambrex Karlskoga Ab | New procedure for preparing 4-substituted imidazoles |
SG11201405606RA (en) | 2012-05-08 | 2014-11-27 | Lonza Ag | Method for preparation of medetomidine |
EP2847157B1 (en) | 2012-05-08 | 2015-10-28 | Lonza Ltd | Method for preparation of 2-(2,3-dimethylphenyl)-1-propanal |
WO2012172119A2 (en) * | 2012-05-08 | 2012-12-20 | Lonza Ltd | Method for the preparation of medetomidine |
AU2012285677B2 (en) * | 2012-06-28 | 2016-03-31 | Lonza Ltd | Method for preparation of medetomidine with chloroacetone |
BR112014022268A8 (en) | 2012-06-28 | 2019-05-28 | Lonza Ag | Method for preparing 2- (2,3-dimethylphenyl) -1-propanal with chloroacetone |
CN106588777A (en) * | 2015-10-16 | 2017-04-26 | 江苏开元医药化工有限公司 | Industrial preparation method of dexmedetomidine hydrochloride |
KR20240148807A (en) | 2022-03-22 | 2024-10-11 | 옵쉐스트바 스 아그라니첸너이아트볫스트벤너스찌유 "빅-즈다로비예쥐보트니흐" | Method for preparing medetomidine and its derivatives |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2101114B (en) * | 1981-07-10 | 1985-05-22 | Farmos Group Ltd | Substituted imidazole derivatives and their preparation and use |
-
2007
- 2007-10-24 GB GB0720891A patent/GB2453982B/en not_active Expired - Fee Related
-
2008
- 2008-10-22 AR ARP080104589A patent/AR068952A1/en unknown
- 2008-10-22 UY UY31415A patent/UY31415A1/en not_active Application Discontinuation
- 2008-10-23 PE PE2008001820A patent/PE20091088A1/en not_active Application Discontinuation
- 2008-10-24 WO PCT/GB2008/003613 patent/WO2009053709A1/en active Application Filing
- 2008-10-24 CL CL2008003185A patent/CL2008003185A1/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114671811A (en) * | 2022-04-14 | 2022-06-28 | 南京正科医药股份有限公司 | Racemization recovery method of dexmedetomidine resolution byproduct |
Also Published As
Publication number | Publication date |
---|---|
GB2453982B (en) | 2009-09-16 |
UY31415A1 (en) | 2009-05-29 |
WO2009053709A1 (en) | 2009-04-30 |
AR068952A1 (en) | 2009-12-16 |
PE20091088A1 (en) | 2009-07-20 |
GB2453982A (en) | 2009-04-29 |
CL2008003185A1 (en) | 2009-03-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1125645 Country of ref document: HK |
|
REG | Reference to a national code |
Ref country code: HK Ref legal event code: GR Ref document number: 1125645 Country of ref document: HK |
|
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20111024 |