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GB0716005D0 - Single molecule spectroscopy using nanoporpus membranes - Google Patents

Single molecule spectroscopy using nanoporpus membranes

Info

Publication number
GB0716005D0
GB0716005D0 GBGB0716005.4A GB0716005A GB0716005D0 GB 0716005 D0 GB0716005 D0 GB 0716005D0 GB 0716005 A GB0716005 A GB 0716005A GB 0716005 D0 GB0716005 D0 GB 0716005D0
Authority
GB
United Kingdom
Prior art keywords
volume
nanoporpus
membranes
single molecule
pore
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0716005.4A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ip2ipo Innovations Ltd
Original Assignee
Imperial Innovations Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Innovations Ltd filed Critical Imperial Innovations Ltd
Priority to GBGB0716005.4A priority Critical patent/GB0716005D0/en
Publication of GB0716005D0 publication Critical patent/GB0716005D0/en
Priority to PCT/GB2008/002776 priority patent/WO2009022152A1/en
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0038—Investigating nanoparticles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Apparatus for characterizing molecules comprises a barrier (10, 14) between a first volume (24) and a second volume (32), the barrier having a pore (18) through it, a pair of electrodes (36, 38) arranged to generate an electrical potential difference between the first and second volumes to drive molecules from the first volume to the second volume, and optical sensing means (44, 40, 42) arranged to detect light from the pore thereby to detect passage of a molecule through the pore.
GBGB0716005.4A 2007-08-16 2007-08-16 Single molecule spectroscopy using nanoporpus membranes Ceased GB0716005D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB0716005.4A GB0716005D0 (en) 2007-08-16 2007-08-16 Single molecule spectroscopy using nanoporpus membranes
PCT/GB2008/002776 WO2009022152A1 (en) 2007-08-16 2008-08-15 Single molecule spectroscopy using nanoporous membranes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0716005.4A GB0716005D0 (en) 2007-08-16 2007-08-16 Single molecule spectroscopy using nanoporpus membranes

Publications (1)

Publication Number Publication Date
GB0716005D0 true GB0716005D0 (en) 2007-09-26

Family

ID=38566507

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0716005.4A Ceased GB0716005D0 (en) 2007-08-16 2007-08-16 Single molecule spectroscopy using nanoporpus membranes

Country Status (2)

Country Link
GB (1) GB0716005D0 (en)
WO (1) WO2009022152A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2781581C (en) * 2009-12-01 2018-03-06 Oxford Nanopore Technologies Limited Biochemical analysis instrument
JP5764296B2 (en) * 2010-03-31 2015-08-19 株式会社日立ハイテクノロジーズ Characterization of biopolymers
WO2012107778A2 (en) 2011-02-11 2012-08-16 Oxford Nanopore Technologies Limited Mutant pores
CN104350067A (en) 2012-04-10 2015-02-11 牛津纳米孔技术公司 mutant lysin pore
GB201313477D0 (en) 2013-07-29 2013-09-11 Univ Leuven Kath Nanopore biosensors for detection of proteins and nucleic acids
CN106459159B (en) 2014-05-02 2021-11-30 牛津纳米孔技术公司 Abrupt change hole
WO2016034591A2 (en) 2014-09-01 2016-03-10 Vib Vzw Mutant pores
US10266885B2 (en) 2014-10-07 2019-04-23 Oxford Nanopore Technologies Ltd. Mutant pores
CN107002126B (en) * 2014-10-24 2021-05-25 昆塔波尔公司 Efficient Optical Analysis of Polymers Using Arrays of Nanostructures
JP6283305B2 (en) * 2014-12-04 2018-02-21 株式会社日立ハイテクノロジーズ Biomolecule measuring apparatus and biomolecule measuring method
EP3402903B1 (en) * 2016-01-15 2022-03-02 Quantapore, Inc. Optically-based nanopore analysis with reduced background
KR102514030B1 (en) 2021-03-31 2023-03-24 고려대학교 산학협력단 Device for single cell analysis using micropore

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1389553A (en) * 1972-05-23 1975-04-03 Legorreta G Apparatus for investigating microscopic particles
WO1998035012A2 (en) * 1997-02-12 1998-08-13 Chan Eugene Y Methods and products for analyzing polymers
US7001792B2 (en) * 2000-04-24 2006-02-21 Eagle Research & Development, Llc Ultra-fast nucleic acid sequencing device and a method for making and using the same
US8278055B2 (en) * 2002-05-01 2012-10-02 Intel Corporation Methods and device for analyte characterization
US20060019259A1 (en) * 2004-07-22 2006-01-26 Joyce Timothy H Characterization of biopolymers by resonance tunneling and fluorescence quenching

Also Published As

Publication number Publication date
WO2009022152A1 (en) 2009-02-19

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)