FR3131844A1 - Composition comprising a high level of panthenol, hyaluronic acid or one of its salts, and a polymer with a sulphonic group - Google Patents

Abstract

Composition comprising a high level of panthenol, hyaluronic acid or one of its salts, and a polymer with a sulphonic group The present invention relates to a composition, preferably cosmetic or dermatological, comprising: at least 6% by weight of panthenol based on the total weight of the composition; at least 0.35% by weight of hyaluronic acid or its salts, or mixtures thereof, based on the total weight of the composition; at least one sulfonic group polymer; a physiologically acceptable medium comprising at least water. The present invention also relates to a cosmetic treatment process comprising the application of said composition to keratin materials as well as the cosmetic use of said composition for caring for the skin.

Description

Composition comprising a high level of panthenol, hyaluronic acid or one of its salts, and a polymer with a sulfonic group

The present invention relates to the field of cosmetic or dermatological care compositions for keratin materials, in particular the skin. The present invention relates to a cosmetic or dermatological composition comprising a high level of panthenol, hyaluronic acid or one of its salts, and a polymer with a sulfonic group, a cosmetic treatment process comprising a step of application on the keratin materials, preferably the skin, of said composition as well as its use for the care of keratin materials, preferably the skin.

In the field of formulating compositions for the care of keratin materials, particularly the skin, one of the major challenges is to introduce high-performance biological active ingredients into these compositions while providing (or keeping) a good level of sensoriality and cosmetic approval in order to encourage the use of these products and thus intensify their effects observed on the skin through regular and repeated use.

In addition, it is important for the consumer to have a concordance between the biological effectiveness of the active ingredient and the immediate sensory effect, particularly from the first application of the composition on keratin materials.

Panthenol, which is an analogue of pantothenic acid (vitamin B5), is a particularly effective active molecule for treating keratin repair issues, in particular for preventing the reduction of and/or strengthening the barrier function of the skin.

To obtain high levels of performance for the repair of keratin materials, these active ingredients can be used at high levels (for example at levels greater than 6% in panthenol active ingredient).

Furthermore, another challenge for the formulator of care products for keratin materials, particularly for the skin, is to offer pleasant and adequate textures in terms of sensoriality for the target consumers. Indeed, consumers likely to use restorative treatments have specific sensory issues and needs for their skin, such as for example a need for enveloping and film-forming textures, notably leaving a protective film on keratin materials such as the skin, like a bandage.

There therefore remains a need to offer compositions enriched with panthenol as an active molecule while providing a good level of sensory pleasure, particularly film-forming.

The applicant has found, surprisingly, that the formulation of more than 6% by weight of panthenol in a composition comprising the combination of at least one polymer with a sulfonic group as well as at least 0.35% by weight of hyaluronic acid or its salts, or their mixtures, provides good sensory pleasure consistent with the restorative activity of the panthenol thus formulated, namely a film-forming effect after application.

1. au moins 6% en poids de panthénol par rapport au poids total de la composition ;
2. au moins 0,35% en poids d’acide hyaluronique ou ses sels, ou leurs mélanges, par rapport au poids total de la composition ;
3. au moins un polymère à groupement sulfonique ;
4. un milieu physiologiquement acceptable comprenant au moins de l’eau.

Thus, the subject of the present invention is a composition, preferably cosmetic or dermatological, comprising:

1. at least 6% by weight of panthenol relative to the total weight of the composition;
2. at least 0.35% by weight of hyaluronic acid or its salts, or mixtures thereof, relative to the total weight of the composition;
3. at least one polymer with a sulfonic group;
4. a physiologically acceptable medium comprising at least water.

The present invention makes it possible to obtain compositions containing a high level of panthenol as an active ingredient while providing good sensory pleasure in terms of film-forming properties after penetration of the composition into the skin.

It thus makes it possible to reinforce the perception of effectiveness of panthenol thanks to immediate effects felt during and/or upon application of the product: enveloping, film-forming effects.

In addition, the composition of the invention has good stability properties.

Thus, it is possible to introduce high levels of panthenol into the composition according to the invention while having sensory properties during the application of the composition consistent with the biological restorative effects of panthenol, for example a film-forming effect after penetration of the composition into the skin.

The present invention also relates to a method of cosmetic treatment for the care of keratin materials, preferably the skin, comprising a step of application to the keratin materials, preferably the skin, of said composition according to the invention.

The invention also relates to the cosmetic use of said composition according to the invention for the care of keratin materials, preferably the skin.

Definitions

By “keratin materials” we generally mean human skin, in particular of the face, the scalp, nails, mucous membranes such as the lips, and also human keratin fibers. In particular, the skin of the face and the scalp are more particularly concerned by the present invention and even more particularly the skin of the face.

In the present application, the term “physiologically acceptable medium” means a medium compatible with all keratin materials such as the skin including the scalp, nails, mucous membranes, eyes, lips, and hair or any other skin area. from the body.

Said physiologically acceptable medium comprises water and optionally one or more organic solvents miscible with water which can be chosen from linear or branched C1-C6 monoalcohols such as ethanol, isopropanol, tertio- butanol; polyols such as glycerol, propylene glycol, hexylene glycol (or 2-methyl-2,4-pentanediol), and polyethylene glycols; polyol ethers such as dipropylene glycol monomethyl ether; and their mixtures.

Preferably, the composition according to the invention has a water content ranging from 20% to 95% by weight, even better from 40% to 90% by weight relative to the total weight of the composition.

Advantageously, the composition according to the invention comprises one or more organic solvents miscible with water in a content ranging from 0.5% to 25% by weight, preferably from 5% to 20% by weight.

By “enveloping effect” is meant the formation of a thick film during the application of the composition.

By “film-forming effect” is meant the formation of an oily film remaining on the skin after application of the composition corresponding to the formation of a protective film also called dressing effect.

By “good stability properties” or “stable composition” is meant a composition showing no or little variation in its organoleptic characteristics at room temperature (25°C), and/or at 4°C and/or at 45°C. C for a period of 2 months.

Detailed description of the invention

Composition

1. au moins 6% en poids de panthénol par rapport au poids total de la composition ;
2. au moins 0,35% en poids d’acide hyaluronique ou ses sels, ou leurs mélanges, par rapport au poids total de la composition ;
3. au moins un polymère à groupement sulfonique ;
4. un milieu physiologiquement acceptable comprenant au moins de l’eau.

The subject of the present invention is a composition, preferably cosmetic or dermatological, comprising:

1. at least 6% by weight of panthenol relative to the total weight of the composition;
2. at least 0.35% by weight of hyaluronic acid or its salts, or mixtures thereof, relative to the total weight of the composition;
3. at least one polymer with a sulfonic group;
4. a physiologically acceptable medium comprising at least water.

Panthenol

Panthenol is an alcohol analogue of pantothenic acid, having the following structure:

(I)

Panthenol is also called provitamin B5, which is only converted to vitamin B5 after it binds with other molecules.

Panthenol may be present in the composition according to the invention in an amount of at least 8% by weight, preferably at least 10% by weight, relative to the total weight of the composition.

In a preferred embodiment, panthenol may be present in the composition according to the invention in an amount ranging from 6% to 20% by weight, preferably ranging from 8% to 15% by weight, even better ranging from 9%. at 11% by weight relative to the total weight of the composition, such as 10% by weight relative to the total weight of the composition.

Hyaluronic acid or its salts

Hyaluronic acid belongs to the glycosaminoglycan (GAGs) family.

GAGs are linear chains composed of the repetition of a basic disaccharide always containing a hexosamine (glucosamine or galactosamine) and another ose (glucuronic acid, iduronic acid or galactose). Glucosamine is either N-sulfated or N-acetylated. In contrast, galactosamine is always N-acetylated. Additionally, there may be O-linked sulfates on hexosamine, uronic acid, and galactose.

Hyaluronic acid or hyaluronan (HA) is the main GAG in the dermis, the latter containing half of the body's HA.

It is a polysaccharide of disaccharides themselves composed of D-glucuronic acid and N-acetylglucosamine, linked together by alternating beta-1,4 and beta-1,3 glycosidic bonds. It plays an important role in the hydration and elasticity of the skin.

The composition according to the invention comprises at least 0.35% by weight of hyaluronic acid or one of its salts, or mixtures thereof, relative to the total weight of the composition.

As salts of hyaluronic acid, we can cite in particular potassium hyaluronate and sodium hyaluronate.

Preferably, according to the invention, sodium hyaluronate will be used.

In particular, sodium hyaluronate with a molecular weight of 1,100,000 Daltons marketed by the company SOLIANCE under the name CRISTALHYAL® may be used in the composition of the invention.

Hyaluronic acid or one of its salts, or their mixtures may be present in the composition according to the invention in an amount of at least 0.40% by weight (of dry matter), preferably at least 0.45% by weight (of dry matter), relative to the total weight of the composition.

In a preferred embodiment, hyaluronic acid or one of its salts, or mixtures thereof may be present in the composition according to the invention in an amount ranging from 0.35% to 5% by weight. (of dry matter) relative to the total weight of the composition, preferably ranging from 0.40% to 2% by weight (of dry matter), even better ranging from 0.45% to 1% by weight (of dry matter). ) relative to the total weight of the composition.

Polymer with sulfonic group

The composition according to the invention comprises a homo or a copolymer of a monomer with a sulfonic group.

The polymers comprising at least one monomer with a sulfonic group, used in the composition of the invention, are advantageously water-soluble or water-dispersible or swellable in water. The polymers used in accordance with the invention are homo or copolymers capable of being obtained from at least one monomer with ethylenic unsaturation and a sulfonic group, which can be in free form or partially or totally neutralized.

Preferably, the polymers according to the invention can be partially or completely neutralized by a mineral base (soda, potassium hydroxide, ammonia) or an organic base such as mono-, di- or tri-ethanolamine, an aminomethylpropanediol, N -methyl-glucamine, basic amino acids such as arginine and lysine, and mixtures of these compounds. They are generally neutralized. In the present invention, the term “neutralized” means totally or practically totally neutralized polymers, that is to say neutralized to at least 90%.

The polymers used in the composition of the invention generally have a number average molecular weight ranging from 1000 to 20,000,000 g/mole, preferably ranging from 20,000 to 5,000,000 and even more preferably from 100,000 to 1,500,000. g/mole.

These polymers according to the invention can be crosslinked or not crosslinked.

The monomers with a sulfonic group of the polymer used in the composition of the invention are chosen in particular from vinylsulfonic acid, styrenesulfonic acid, (meth)acrylamido-(C1 C22)alkylsulfonic acids, N-(C1-C22) acids. )alkyl-(meth)acrylamido-(C1 C22)-alkylsulfonic acids such as undecyl-acrylamido-methane-sulfonic acid, as well as their partially or totally neutralized forms, and their mixtures.

According to a preferred embodiment of the invention, the monomers with a sulfonic group are chosen from (meth)acrylamido(C1-C22)alkylsulfonic acids such as for example acrylamido-methane-sulfonic acid, acrylamido-ethane acid -sulfonic acid, acrylamido-propane-sulfonic acid, 2-acrylamido-2-methylpropane-sulfonic acid, 2-methacrylamido-2-methylpropane-sulfonic acid, 2-acrylamido-n-butane-sulfonic acid , 2-acrylamido-2,4,4-trimethylpentane-sulfonic acid, 2-methacrylamido-dodecyl-sulfonic acid, 2-acrylamido-2,6-dimethyl-3-heptane-sulfonic acid, as well as their partially or totally neutralized forms, and their mixtures.

More particularly, 2-acrylamido-2-methylpropanesulfonic acid (AMPS) is used as well as its partially or completely neutralized forms.

When the polymers are crosslinked, the crosslinking agents can be chosen from polyolefinically unsaturated compounds commonly used for the crosslinking of polymers obtained by radical polymerization.

Mention may be made, for example, as crosslinking agents, divinylbenzene, diallyl ether, dipropylene glycol-diallyl ether, polyglycol-diallyl ethers, triethylene glycol-divinyl ether, hydroquinone-diallyl ether, di(meth)acrylate of ethylene glycol or tetraethylene glycol, trimethylol propane triacrylate, methylene-bis-acrylamide, methylene-bis-methacrylamide, triallylamine, triallylcyanurate, diallylmaleate, tetraallylethylenediamine, tetra-allyloxy-ethane, trimethylolpropane-diallylether, ( allyl meth)acrylate, allyl ethers of alcohols of the sugar series, or other allyl- or vinyl ethers of polyfunctional alcohols, as well as allyl esters of phosphoric and/or vinylphosphonic acid derivatives , or mixtures of these compounds.

According to a preferred embodiment of the invention, the crosslinking agent is chosen from methylene-bis-acrylamide, allyl methacrylate or trimethylol propane triacrylate (TMPTA). The crosslinking rate generally ranges from 0.01 to 10 mol% and more particularly from 0.2 to 2 mol% relative to the polymer.

The homopolymer of monomers with a sulfonic group can be crosslinked with one or more crosslinking agents.

1. on disperse ou on dissout le monomère tel que l’acide 2-acrylamido 2-méthylpropane sulfonique sous forme libre dans une solution de tertio-butanol ou d’eau et de tertio-butanol ;
2. on neutralise la solution ou la dispersion de monomère obtenue en (a) par une ou plusieurs bases minérales ou organiques, de préférence l’ammoniaque NH3, dans une quantité permettant d’obtenir un taux de neutralisation des fonctions acides sulfoniques du polymère allant de 90 à 100% ;
3. on ajoute à la solution ou dispersion obtenue en (b), le ou les monomères réticulants ;
4. on effectue une polymérisation radicalaire classique en la présence d’amorceurs de radicaux libres à une température allant de 10 à 150°C ; le polymère précipitant dans la solution ou la dispersion à base de tertio-butanol.

These homopolymers are generally crosslinked and neutralized, and they can be obtained according to the preparation process comprising the following steps:

1. the monomer such as 2-acrylamido 2-methylpropane sulfonic acid is dispersed or dissolved in free form in a solution of tert-butanol or water and tert-butanol;
2. the solution or dispersion of monomer obtained in (a) is neutralized with one or more mineral or organic bases, preferably ammonia NH3, in an amount making it possible to obtain a neutralization rate of the sulfonic acid functions of the polymer ranging from 90 100% ;
3. the crosslinking monomer(s) is added to the solution or dispersion obtained in (b);
4. a conventional radical polymerization is carried out in the presence of free radical initiators at a temperature ranging from 10 to 150°C; the polymer precipitating in the solution or dispersion based on tertio-butanol.

1. de 90 à 99,9% en poids de motifs de formule générale (II) suivante :
   [Chem 2]
   (II)
   dans laquelle X+ désigne un proton, un cation de métal alcalin, un cation alcalino-terreux ou l’ion ammonium, au plus 10% mol des cations X+ pouvant être des protons H+ ;
2. de 0,01 à 10% en poids de motifs réticulants provenant d’au moins un monomère ayant au moins deux double-liaison oléfiniques ; les proportions en poids étant définis par rapport au poids total du polymère.

The preferred AMPS homopolymers are generally characterized by the fact that they comprise, distributed randomly:

1. from 90 to 99.9% by weight of units of general formula (II):
   [Chem 2]
   (II)
   in which X+ designates a proton, an alkali metal cation, an alkaline earth cation or the ammonium ion, at most 10 mol% of the
2. from 0.01 to 10% by weight of crosslinking units originating from at least one monomer having at least two olefinic double bonds; the proportions by weight being defined relative to the total weight of the polymer.

The more particularly preferred homopolymers according to the invention comprise from 98 to 99.5% by weight of units of formula (II) and from 0.2 to 2% by weight of crosslinking units.

As polymers of this type, we can cite in particular the crosslinked and neutralized homopolymer of 2-acrylamido 2-methylpropane sulfonic acid, marketed by the company Clariant under the trade name “Hostacerin® AMPS” (CTFA name: ammonium polyacryldimethyltauramide).

The polymer with a sulfonic group may be present in the composition according to the invention in an amount ranging from 0.05 to 5% by weight, preferably ranging from 0.1 to 5% by weight, preferably ranging from 0.1 to 2 % by weight, even better from 0.20% by weight to 0.50% by weight relative to the total weight of the composition.

In order for the cosmetic or dermatological compositions of the invention to be more pleasant to use (softer on application, more nourishing, more emollient), it is possible to add an oily phase (or fatty phase) to the medium of these compositions.

This oily phase contains one or more oils, namely organic substances that are liquid at room temperature (20 to 25°C) and atmospheric pressure (760 mm Hg).

When it is present, the oily phase preferably represents 0.1% to 50% of the total weight of the composition, better still 1 to 30% and even better 5 to 20% of the total weight of the composition.

As oils which can be used in the composition of the invention, we can cite for example:
- hydrocarbon oils of animal origin, such as perhydrosqualene;
- hydrocarbon oils of plant origin distinct from the two hydrogenated or non-hydrogenated polyoxyethylene vegetable oils, such as liquid triglycerides of fatty acids containing 4 to 10 carbon atoms such as the triglycerides of heptanoic or octanoic acids or, for example, sunflower, corn, soy, squash, grape seed, sesame, hazelnut, apricot, macadamia, arara, sunflower, castor, avocado oils, caprylic acid triglycerides / capric like those sold by the company Stearineries Dubois or those sold under the names Miglyol 810, 812 and 818 by the company Dynamit Nobel, jojoba oil, shea butter oil;
- synthetic esters and ethers, in particular of fatty acids, such as oils of formulas R1COOR2 and R1OR2 in which R1 represents the remainder of a fatty acid comprising 8 to 29 carbon atoms, and R2 represents a hydrocarbon chain, branched or not, containing 3 to 30 carbon atoms, such as for example Purcellin oil, isononyl isononanoate, isopropyl myristate, ethyl-2-hexyl palmitate, octyl stearate -2-dodecyl, octyl-2-dodecyl erucate, isostearyl isostearate; hydroxylated esters such as isostearyl lactate, octylhydroxystearate, octyldodecyl hydroxystearate, diisostearyl malate, triisocetyl citrate, heptanoates, octanoates, decanoates of fatty alcohols; polyol esters, such as propylene glycol dioctanoate, neopentyl glycol diheptanoate and diethylene glycol diisononanoate; and pentaerythritol esters such as pentaerythrytyl tetraisostearate;
- linear or branched hydrocarbons, of mineral or synthetic origin, such as paraffin oils, volatile or not, and their derivatives, petroleum jelly, polydecenes, hydrogenated polyisobutene such as Parléam oil;
- fatty alcohols having 8 to 26 carbon atoms, such as cetyl alcohol, stearyl alcohol and their mixture (cetylstearyl alcohol), octyl dodecanol, 2-butyloctanol, 2-hexyldecanol, 2-undecylpentadecanol , oleic alcohol or linoleic alcohol;
- partially hydrocarbon and/or silicone fluorinated oils such as those described in document JP-A-2-295912;
- silicone oils such as volatile or non-volatile polymethylsiloxanes (PDMS) with a linear or cyclic silicone chain, liquid or pasty at room temperature, in particular cyclopolydimethylsiloxanes (cyclomethicones) such as cyclohexasiloxane; polydimethylsiloxanes comprising alkyl, alkoxy or phenyl groups, during or at the end of a silicone chain, groups having from 2 to 24 carbon atoms; phenyl silicones such as phenyltrimethicones, phenyldimethicones, phenyltrimethylsiloxydiphenyl-siloxanes, diphenyl-dimethicones, diphenylmethyldiphenyltrisiloxanes, 2-phenylethyltrimethyl-siloxysilicates, and polymethylphenylsiloxanes;
- their mixtures.

The term “hydrocarbon oil” in the list of oils cited above means any oil comprising predominantly carbon and hydrogen atoms, and possibly ester, ether, fluorinated, carboxylic acid and/or alcohol groups.

Other fatty substances that may be present in the oily phase are, for example, fatty acids containing 8 to 30 carbon atoms, such as stearic acid, lauric acid, palmitic acid and oleic acid; waxes such as lanolin, beeswax, Carnauba or Candellila wax, paraffin waxes, lignite waxes or microcrystalline waxes, ceresin or ozokerite, synthetic waxes such as polyethylene waxes, waxes of Fischer-Tropsch; gums such as silicone gums (dimethiconol); silicone resins such as trifluoromethyl-C1-4-alkyldimethicone and trifluoropropyldimethicone; and silicone elastomers such as the products marketed under the names “KSG” by the company Shin-Etsu, under the names “Trefil”, “BY29” or “EPSX” by the company Dow Corning or under the names “Gransil” by the company Grant Industries company.

These fatty substances can be chosen in a variety of ways by those skilled in the art in order to prepare a composition having the desired properties, for example of consistency or texture.

In known manner, the compositions of the invention may also contain adjuvants usual in the cosmetic and dermatological fields, other conventional aqueous or lipophilic gelling agents and/or thickeners; hydrophilic or lipophilic active ingredients; conservatives; antioxidants; perfumes ; emollients; sequestrants; surfactants; polymers; alkanizing or acidifying agents; charges ; anti-free radical agents; solar filters (especially ultraviolet); coloring materials (such as pigments, soluble dyes or pearls). The quantities of these different adjuvants are those conventionally used in the fields considered, for example quantities ranging from 0.001% to 20% by weight relative to the total weight of the composition.

Of course, those skilled in the art will take care to choose the possible compound(s) to be added to the composition according to the invention in such a way that the advantageous properties inherently attached to the composition according to the invention are not, or substantially not altered by the planned addition.

The compositions according to the invention can be presented in all forms suitable for topical application, in particular in the form of solutions of the lotion or serum type, in the form of aqueous gels, hydroalcoholic gel, in the form of emulsions obtained by dispersion of a fatty phase in an aqueous phase (O/W) or vice versa (W/O) or in the form of multiple emulsions (O/W/O or W/O/W), of liquid or semi-liquid consistency such as milks, more or less creamy creams, gel creams, pastes. They can optionally be packaged in an aerosol and come in the form of foam or spray. These compositions are prepared according to the usual methods.

In a preferred embodiment, the composition according to the invention is in the form of an aqueous gel.

The composition of the invention can have a viscosity adapted to the product that it is desired to obtain. This viscosity can range for example from 2 to 20 poises (0.2 to 2 Pa.s), more particularly from 3 to 10 poises (0.3 to 1 Pa.s), even better from 3 to 6 poises (0. 3 to 0.6 Pa.s) measured at ambient temperature (approximately 25°C) with a Rhéomat 180 type viscometer using a mobile 2, at 200 s-1.

When the composition is an emulsion, the oily phase contains one or more oils and possibly other fatty substances, as described above. The proportion of the oily phase of the emulsion can range for example from 5 to 80% by weight, and preferably from 5 to 50% by weight relative to the total weight of the composition. The aqueous phase represents the 100% complement by weight.

Advantageously, according to a particular embodiment of the invention, the emulsions prepared with the polymers according to the invention can be free of emulsifiers, while being stable on storage, whatever the temperature (for example between 5 and 50°C).

Thus, the compositions of the invention can be used as care and/or hygiene products, such as protection, treatment or care creams for the face, for the hands or for the body, body milks of protection or care, lotions, gels or foams for the care of the skin and mucous membranes or for cleaning or exfoliating the skin.

Cosmetic treatment process

The present invention also relates to a cosmetic treatment process for the care of keratin materials, preferably the skin, comprising a step of application to the keratin materials, preferably the skin, of the composition according to the invention.

Cosmetic use

The present invention further relates to the cosmetic use of the composition according to the invention for the care of keratin materials, preferably the skin.

The composition according to the invention can be used in many cosmetic or dermatological applications where the presence of panthenol is useful, in particular it can be used to prevent the reduction of and/or strengthen the barrier function of the skin.

Throughout the description, including the claims, the expression “at least one” is to be understood as being synonymous with “one or more” unless otherwise specified.

The expressions “more than”, “between… and…” and “ranging from… to…” must be understood inclusive, unless otherwise specified.

The examples and figures which follow are presented by way of illustration and not limitation of the invention. The compounds are, depending on the case, cited in chemical names or in CTFA names (International Cosmetic Ingredient Dictionary and Handbook).
Example - Comparative study of the sensoriality (+/- film-forming effect) of compositions 1 (according to the invention) and 2 (excluding the invention)

The 2 gel-type compositions below were prepared.

INCI (EU) Composition 1 according to the invention Composition 2 outside invention OCTYLDODECANOL 0.5 0.5 PHENOXYETHANOL 0.5 0.5 ALCOHOL DENAT. 5 5 WATER 71.46 71.61 PEG-20 METHYL GLUCOSE SESQUISTEARATE 0.1 0.1 SODIUM HYALURONATE 0.45 0.3 GLYCERIN 5 5 DIMETHICON 1 1 XANTHAN GUM 0.1 0.1 CAPRYLYL GLYCOL 0.3 0.3 AMMONIUM POLYACRYLOYLDIMETHYL TAURATE 0.25 0.25 HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID 1 1 PANTHENOL 13.34 (10% active ingredient) 13.34 (10% active ingredient)) VITREOSCILLA FERMENT 1 1

1. A température ambiante, introduire l’eau, panthenol, Vitreoscilla ferment, Glycerine, Octyldodecanol, PEG-20 methyl glucose sesquistearate, Phenoxyethal, Caprylyl Glycol, Hydroxyethylpiperazine ethane sulphonique acide, disperser jusqu'à obtention d'un liquide homogène.
2. Introduire le Sodium Hyaluronate, Ammonium Polyacryloyldimethyl taurate et xanthan gum, disperser jusqu'à obtention d'un jus homogène lisse et sans grains.
3. Introduire le dimethicone et disperser jusqu'à obtention d'un jus homogène et d'une émulsion conforme.
4. Introduire l’alcool denaturé et disperser jusqu'à l'obtention d'un jus homogène.
5. Désaérer si nécessaire.

Manufacturing process :

1. At room temperature, introduce water, panthenol, Vitreoscilla ferment, Glycerin, Octyldodecanol, PEG-20 methyl glucose sesquistearate, Phenoxyethal, Caprylyl Glycol, Hydroxyethylpiperazine ethane sulphonic acid, disperse until a homogeneous liquid is obtained.
2. Introduce Sodium Hyaluronate, Ammonium Polyacryloyldimethyl taurate and xanthan gum, disperse until a smooth, grain-free homogeneous juice is obtained.
3. Introduce the dimethicone and disperse until a homogeneous juice and a consistent emulsion are obtained.
4. Introduce the denatured alcohol and disperse until a homogeneous juice is obtained.
5. Deaerate if necessary.

Evaluation of the film-forming effect

Test protocol:

Compositions 1 (according to the invention) and 2 (excluding the invention) were applied to the half-face, in the form of a single application, on 12 volunteers.

The volunteers were invited to apply compositions 1 (according to the invention) and 2 (excluding the invention) in the same way and in the same quantities as they are used to doing in their skin care routine.

Each volunteer received a comparative questionnaire, with a 6-point scale to evaluate the film-forming effect after application (0 corresponding to no film-forming effect and 6 corresponding to a very film-forming effect).

Results :

Average of the “film-forming effect” scores for composition 1 (according to the invention) Average “film-forming effect” scores for composition 2 (excluding invention) 2.7 2

Conclusion: A greater film-forming effect is observed with composition 1 according to the invention.

Claims (10)

Composition, preferably cosmetic or dermatological, comprising:

1. at least 6% by weight of panthenol relative to the total weight of the composition;
2. at least 0.35% by weight of hyaluronic acid or its salts, or mixtures thereof, relative to the total weight of the composition;
3. at least one polymer with a sulfonic group;
4. a physiologically acceptable medium comprising at least water.

Composition according to claim 1, in which the panthenol is present in the composition in an amount of at least 8% by weight, preferably at least 10% by weight, relative to the total weight of the composition. Composition according to claim 1 or 2, in which the polymer with a sulfonic group is a polymer of 2-acrylamido 2-methylpropane sulfonic acid. Composition according to any one of the preceding claims, in which the polymer with a sulfonic group is a crosslinked homopolymer of 2-acrylamido 2-methylpropane sulfonic acid. Composition according to any one of the preceding claims, in which the polymer with a sulfonic group is present in the composition in an amount ranging from 0.05% to 5% by weight, preferably ranging from 0.1% to 5% by weight , preferably ranging from 0.1% to 2% by weight, even better from 0.20% to 0.50% by weight relative to the total weight of the composition. Composition according to any one of the preceding claims, in which hyaluronic acid or its salts, or mixtures thereof, is(are) present in the composition in an amount of at least 0.40% by weight (of dry matter), preferably at least 0.45% by weight (of dry matter), relative to the total weight of the composition. Composition according to any one of the preceding claims, characterized in that it is in the form of an aqueous gel. Cosmetic treatment process for the care of keratin materials, preferably the skin, comprising a step of applying to the keratin materials, preferably the skin, the composition according to any one of claims 1 to 7. Cosmetic use of the composition according to any one of claims 1 to 7 for the care of keratin materials, preferably the skin. Cosmetic use of the composition according to any one of claims 1 to 7 to prevent the reduction of and/or strengthen the barrier function of the skin.