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FR3126617B1 - compositions comprising extracellular vesicles, secreted biomolecules and/or conditioned media, and methods for producing them - Google Patents

compositions comprising extracellular vesicles, secreted biomolecules and/or conditioned media, and methods for producing them Download PDF

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Publication number
FR3126617B1
FR3126617B1 FR2109323A FR2109323A FR3126617B1 FR 3126617 B1 FR3126617 B1 FR 3126617B1 FR 2109323 A FR2109323 A FR 2109323A FR 2109323 A FR2109323 A FR 2109323A FR 3126617 B1 FR3126617 B1 FR 3126617B1
Authority
FR
France
Prior art keywords
compositions
methods
conditioned media
extracellular vesicles
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR2109323A
Other languages
French (fr)
Other versions
FR3126617A1 (en
Inventor
Daniel Roy
Charbel Bouez
Sarah Hubert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Priority to FR2109323A priority Critical patent/FR3126617B1/en
Priority to US17/877,814 priority patent/US20230043556A1/en
Priority to PCT/US2022/038967 priority patent/WO2023009874A1/en
Priority to CA3227399A priority patent/CA3227399A1/en
Priority to KR1020247006877A priority patent/KR20240041368A/en
Priority to JP2023577754A priority patent/JP2024529240A/en
Publication of FR3126617A1 publication Critical patent/FR3126617A1/en
Application granted granted Critical
Publication of FR3126617B1 publication Critical patent/FR3126617B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/985—Skin or skin outgrowth, e.g. hair, nails
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

compositions comprenant des vésicules extracellulaires, des biomolécules sécrétées et/ou des milieux conditionnés, et procédés pour les produire La divulgation concerne de nouvelles compositions comprenant des 1) milieux conditionnés, 2) des combinaisons de biomolécules sécrétées/molécules organiques, et/ou 3) des vésicules extracellulaires sécrétées/exosomes prélevées à partir d'une culture de cellules épithéliales différenciées, tous uniques, ainsi que des procédés de fabrication et d'utilisation de telles compositions. Figure pour l'abrégé : 1compositions comprising extracellular vesicles, secreted biomolecules and/or conditioned media, and methods for producing them. The disclosure relates to novel compositions comprising 1) conditioned media, 2) combinations of secreted biomolecules/organic molecules, and/or 3) secreted extracellular vesicles/exosomes collected from a culture of differentiated epithelial cells, all unique, as well as methods of making and using such compositions. Figure for abstract: 1

FR2109323A 2021-07-30 2021-09-06 compositions comprising extracellular vesicles, secreted biomolecules and/or conditioned media, and methods for producing them Active FR3126617B1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR2109323A FR3126617B1 (en) 2021-09-06 2021-09-06 compositions comprising extracellular vesicles, secreted biomolecules and/or conditioned media, and methods for producing them
US17/877,814 US20230043556A1 (en) 2021-07-30 2022-07-29 Compositions comprising extracellular vesicles, secreted biomolecules, and/or conditioned media, and methods of producing and using the same
PCT/US2022/038967 WO2023009874A1 (en) 2021-07-30 2022-07-30 Compositions comprising extracellular vesicles, secreted biomolecules, and/or conditioned media, and methods of producing and using the same
CA3227399A CA3227399A1 (en) 2021-07-30 2022-07-30 Compositions comprising extracellular vesicles, secreted biomolecules, and/or conditioned media, and methods of producing and using the same
KR1020247006877A KR20240041368A (en) 2021-07-30 2022-07-30 Compositions comprising extracellular vesicles, secreted biomolecules, and/or conditioned media, and methods of making and using the same
JP2023577754A JP2024529240A (en) 2021-07-30 2022-07-30 Compositions Comprising Extracellular Vesicles, Secreted Biomolecules, and/or Conditioned Media, and Methods of Making and Using Same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR2109323 2021-09-06
FR2109323A FR3126617B1 (en) 2021-09-06 2021-09-06 compositions comprising extracellular vesicles, secreted biomolecules and/or conditioned media, and methods for producing them

Publications (2)

Publication Number Publication Date
FR3126617A1 FR3126617A1 (en) 2023-03-10
FR3126617B1 true FR3126617B1 (en) 2023-12-29

Family

ID=79171333

Family Applications (1)

Application Number Title Priority Date Filing Date
FR2109323A Active FR3126617B1 (en) 2021-07-30 2021-09-06 compositions comprising extracellular vesicles, secreted biomolecules and/or conditioned media, and methods for producing them

Country Status (1)

Country Link
FR (1) FR3126617B1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6372494B1 (en) 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
WO2007070850A2 (en) * 2005-12-14 2007-06-21 Organogenesis, Inc. Skin care compositions and treatments
EP3308795A1 (en) * 2016-10-12 2018-04-18 Unicyte EV AG A composition of extracellular vesicles (evs) and medical uses thereof
JP7394122B2 (en) * 2019-04-19 2023-12-07 富士フイルム株式会社 Storage stabilizing agent and storage stabilization method for extracellular vesicles

Also Published As

Publication number Publication date
FR3126617A1 (en) 2023-03-10

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