[go: up one dir, main page]

FR3017294B1 - LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY - Google Patents

LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY Download PDF

Info

Publication number
FR3017294B1
FR3017294B1 FR1450964A FR1450964A FR3017294B1 FR 3017294 B1 FR3017294 B1 FR 3017294B1 FR 1450964 A FR1450964 A FR 1450964A FR 1450964 A FR1450964 A FR 1450964A FR 3017294 B1 FR3017294 B1 FR 3017294B1
Authority
FR
France
Prior art keywords
antibiotic
nanocapsules
lipid
therapy
lipid nanoparticles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1450964A
Other languages
French (fr)
Other versions
FR3017294A1 (en
Inventor
Amokrane Reghal
Gilles Potel
Jacqueline Caillon
Cedric Jacqueline
Karim Asehoune
Maud Gonnet
Thomas Perrier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ATLANGRAM
Original Assignee
ATLANGRAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ATLANGRAM filed Critical ATLANGRAM
Priority to FR1450964A priority Critical patent/FR3017294B1/en
Priority to PCT/IB2015/050913 priority patent/WO2015118496A1/en
Publication of FR3017294A1 publication Critical patent/FR3017294A1/en
Application granted granted Critical
Publication of FR3017294B1 publication Critical patent/FR3017294B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention se rapporte à des nanocapsules lipidiques comprenant un cœur lipidique liquide ou semi-liquide à température ambiante dans lequel est incorporé au moins un antibiotique, le cœur étant enveloppé d'une enveloppe lipidique solide à température ambiante, et à une composition pharmaceutique comprenant de telles nanocapsules pour traiter ou prévenir une infection bactérienne touchant une articulation, un os ou la peau. La présente invention porte également sur des dispositifs médicaux comprenant de telles nanocapsules ou composition pharmaceutiques.The present invention relates to lipid nanocapsules comprising a liquid or semi-liquid lipid core at ambient temperature in which at least one antibiotic is incorporated, the core being enveloped in a lipid envelope which is solid at ambient temperature, and to a pharmaceutical composition comprising such nanocapsules for treating or preventing bacterial infection affecting a joint, bone or skin. The present invention also relates to medical devices comprising such nanocapsules or pharmaceutical compositions.

FR1450964A 2014-02-07 2014-02-07 LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY Active FR3017294B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1450964A FR3017294B1 (en) 2014-02-07 2014-02-07 LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY
PCT/IB2015/050913 WO2015118496A1 (en) 2014-02-07 2015-02-06 Lipid nanocapsules containing an antibiotic and therapeutic uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1450964A FR3017294B1 (en) 2014-02-07 2014-02-07 LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY

Publications (2)

Publication Number Publication Date
FR3017294A1 FR3017294A1 (en) 2015-08-14
FR3017294B1 true FR3017294B1 (en) 2021-10-01

Family

ID=50624776

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1450964A Active FR3017294B1 (en) 2014-02-07 2014-02-07 LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY

Country Status (2)

Country Link
FR (1) FR3017294B1 (en)
WO (1) WO2015118496A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3679928A1 (en) 2019-01-08 2020-07-15 Atlangram Gel type pharmaceutical composition for treating/preventing an infection
MX2021015513A (en) 2019-06-14 2022-04-20 Debiopharm Int Sa MEDICINE AND USE THEREOF TO TREAT BACTERIAL INFECTIONS INVOLVING A BIFILM.
CN112263395B (en) * 2020-09-18 2021-12-14 浙江珍琦护理用品有限公司 Panty-shape diapers convenient to adjust size
CN118987169B (en) * 2024-10-18 2024-12-17 四川大学 Daptomycin nano preparation and preparation method and application thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2805761B1 (en) 2000-03-02 2002-08-30 Mainelab LIPID NANOCAPSULES, METHOD OF PREPARATION AND USE AS A MEDICAMENT
FR2840532B1 (en) * 2002-06-11 2005-05-06 Ethypharm Sa FURENT LIPID NANOCAPSULES, PROCESS FOR THEIR PREPARATION AND USE AS VECTOR OF ACTIVE (S) PRINCIPLES
FR2916973B1 (en) 2007-06-11 2010-02-26 Univ Angers NANOCAPSULES WITH LIPIDIC HEAD CHARGED WITH HYDROSOLUBLE (S) OR HYDRODISPERSIBLE ACTIVE (S)
FR2916974B1 (en) 2007-06-11 2010-11-26 Univ Angers PROCESS FOR THE PREPARATION OF LIPID NANOPARTICLES
FR2939699B1 (en) 2008-12-12 2011-05-06 Univ Angers PROCESS FOR THE PREPARATION OF LIPID NANOPARTICLES
CA2827239A1 (en) * 2011-02-25 2012-08-30 Universite D'angers Nanocapsulation of essential oils for preventing or curing infectious diseases alone or with an antibiotic

Also Published As

Publication number Publication date
FR3017294A1 (en) 2015-08-14
WO2015118496A4 (en) 2015-10-08
WO2015118496A1 (en) 2015-08-13

Similar Documents

Publication Publication Date Title
FR3017294B1 (en) LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY
MA44549A1 (en) Immunoregulatory agents
MA40814A1 (en) Pharmaceutical compositions for combination therapy
MA42859B2 (en) Antimicrobial compositions and methods of use thereof.
MA28660B1 (en) COMPOUNDS AND COMPOSITIONS AS MODULATORS OF PPAR
MA38576B2 (en) Sustained-release colchicine formulations and methods of use thereof
MA33219B1 (en) SUBSTITUTED AZOANTHRACENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE
MA41083A1 (en) Pharmaceutical Compositions for Combination Therapy
EP2638910A4 (en) COMPOSITION COMPRISING BENPROPERINE DERIVATIVES AS ACTIVE INGREDIENTS FOR THE PREVENTION AND TREATMENT OF ANGIOGENESIS RELATED DISEASES
MA38484B2 (en) Antimicrobial compositions and methods of use
MA39346B1 (en) Fusion-linked substituted heterocycles as gpr119 modulators for the treatment of diabetes, obesity, dyslipidemia and related disorders
WO2015128403A3 (en) An a22k, desb27, b29r, des b30, at epsilon position of lysine 22 acylated human insulin analogue
FR3065371B1 (en) TOPICAL PHARMACEUTICAL COMPOSITION INCLUDING AT LEAST AMITRIPTYLINE FOR THE TREATMENT OF PERIPHERAL NEUROPATHIC PAIN
EP4005572A4 (en) BENZAMIDE DERIVATIVE, METHOD FOR PREPARING IT, AND PHARMACEUTICAL COMPOSITION COMPRISING IT AS AN ACTIVE SUBSTANCE FOR THE PREVENTION OR TREATMENT OF CANCER
MA52438A (en) STERILE OR STERILIZED PACKAGING FOR THE ADMINISTRATION OF MEDICINAL OR NUTRITIONAL SUBSTANCES.
FR2992861A1 (en) USE OF THIOSULFATE FOR POTENTIATING THE ANTI-PATHOGENIC EFFECT OF LACTOBACILLES
EP3443975A4 (en) PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING HEARING LOSS COMPRISING OATOUS EXTRACT AS ACTIVE INGREDIENT
TN2016000078A1 (en) LUBRICANT COMPLEX FOR THE MOUTH
MA54276B1 (en) MONTELUKAST FOR THE TREATMENT OF HAND OSTEOARTHRITIS
WO2016191458A3 (en) Pharmaceutical compositions affecting mitochondrial redox state and methods of treatment
FR3064180B1 (en) FORMULATIONS COMPRISING ACTIVE INGREDIENTS FROM THE MURRAYA KOENIGII PLANT
FR3061013B1 (en) COMPOSITION CONTAINING DIGENEASIDE, PROCESS FOR OBTAINING SAME AND ITS COSMETIC, VETERINARY OR NUTRACEUTICAL USE
MX2020007750A (en) Pharmaceutical package for prevention and/or treatment of covid-19 disease and use thereof.
EP3795170C0 (en) PHARMACEUTICAL COMPOSITION COMPRISING CCN5 USED AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION OR TREATMENT OF RETINAL DISEASE
MA53898B1 (en) 4-pyrazin-2-ylmethyl-morpholine derivatives and their use as medicine

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 3

PLFP Fee payment

Year of fee payment: 4

PLFP Fee payment

Year of fee payment: 5

PLFP Fee payment

Year of fee payment: 7

PLFP Fee payment

Year of fee payment: 8

PLFP Fee payment

Year of fee payment: 9

PLFP Fee payment

Year of fee payment: 10

PLFP Fee payment

Year of fee payment: 11