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FR2986668B1 - Module d'excitation multi-couleurs pour un systeme d'imagerie multi-photonique, systeme et procede associes. - Google Patents

Module d'excitation multi-couleurs pour un systeme d'imagerie multi-photonique, systeme et procede associes.

Info

Publication number
FR2986668B1
FR2986668B1 FR1250990A FR1250990A FR2986668B1 FR 2986668 B1 FR2986668 B1 FR 2986668B1 FR 1250990 A FR1250990 A FR 1250990A FR 1250990 A FR1250990 A FR 1250990A FR 2986668 B1 FR2986668 B1 FR 2986668B1
Authority
FR
France
Prior art keywords
excitation module
imaging system
color excitation
photonic imaging
photonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1250990A
Other languages
English (en)
Other versions
FR2986668A1 (fr
Inventor
Pierre Mahou
Emmanuel Jean-Marc Beaurepaire
Delphine Debarre
Willy Supatto
Jean-Louis Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ECOLE POLYTECH
Centre National de la Recherche Scientifique CNRS
Ecole Polytechnique
Original Assignee
ECOLE POLYTECH
Centre National de la Recherche Scientifique CNRS
Ecole Polytechnique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ECOLE POLYTECH, Centre National de la Recherche Scientifique CNRS, Ecole Polytechnique filed Critical ECOLE POLYTECH
Priority to FR1250990A priority Critical patent/FR2986668B1/fr
Priority to PCT/EP2013/052002 priority patent/WO2013113861A1/fr
Priority to US14/376,040 priority patent/US20140367591A1/en
Priority to JP2014555215A priority patent/JP6254096B2/ja
Priority to EP13705115.7A priority patent/EP2810050A1/fr
Publication of FR2986668A1 publication Critical patent/FR2986668A1/fr
Application granted granted Critical
Publication of FR2986668B1 publication Critical patent/FR2986668B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B17/00—Systems with reflecting surfaces, with or without refracting elements
    • G02B17/02—Catoptric systems, e.g. image erecting and reversing system
    • G02B17/023—Catoptric systems, e.g. image erecting and reversing system for extending or folding an optical path, e.g. delay lines
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6419—Excitation at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G01N21/3151—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths using two sources of radiation of different wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6402—Atomic fluorescence; Laser induced fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06113—Coherent sources; lasers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/066—Modifiable path; multiple paths in one sample
    • G01N2201/0668—Multiple paths; optimisable path length
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/069—Supply of sources
    • G01N2201/0696—Pulsed
    • G01N2201/0697—Pulsed lasers

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
FR1250990A 2012-02-02 2012-02-02 Module d'excitation multi-couleurs pour un systeme d'imagerie multi-photonique, systeme et procede associes. Active FR2986668B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR1250990A FR2986668B1 (fr) 2012-02-02 2012-02-02 Module d'excitation multi-couleurs pour un systeme d'imagerie multi-photonique, systeme et procede associes.
PCT/EP2013/052002 WO2013113861A1 (fr) 2012-02-02 2013-02-01 Module d'excitation multi-couleurs pour un systeme d'imagerie multi-photonique, systeme et procede associes
US14/376,040 US20140367591A1 (en) 2012-02-02 2013-02-01 Multicolour excitation module for a multiphoton imaging system and associated method and system
JP2014555215A JP6254096B2 (ja) 2012-02-02 2013-02-01 多光子イメージングシステム用多色励起モジュール並びにそれに関連する方法及びシステム
EP13705115.7A EP2810050A1 (fr) 2012-02-02 2013-02-01 Module d'excitation multi-couleurs pour un systeme d'imagerie multi-photonique, systeme et procede associes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1250990A FR2986668B1 (fr) 2012-02-02 2012-02-02 Module d'excitation multi-couleurs pour un systeme d'imagerie multi-photonique, systeme et procede associes.

Publications (2)

Publication Number Publication Date
FR2986668A1 FR2986668A1 (fr) 2013-08-09
FR2986668B1 true FR2986668B1 (fr) 2014-02-21

Family

ID=47740907

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1250990A Active FR2986668B1 (fr) 2012-02-02 2012-02-02 Module d'excitation multi-couleurs pour un systeme d'imagerie multi-photonique, systeme et procede associes.

Country Status (5)

Country Link
US (1) US20140367591A1 (fr)
EP (1) EP2810050A1 (fr)
JP (1) JP6254096B2 (fr)
FR (1) FR2986668B1 (fr)
WO (1) WO2013113861A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103576411B (zh) * 2013-09-13 2016-08-17 中国科学院上海光学精密机械研究所 多色飞秒激光产生装置
JP6307903B2 (ja) * 2014-02-04 2018-04-11 株式会社Ihi 物質特定方法および物質特定システム
EP2976015B1 (fr) 2014-02-21 2017-06-07 3DIntegrated ApS Ensemble comprenant un instrument chirurgical
US11020144B2 (en) 2015-07-21 2021-06-01 3Dintegrated Aps Minimally invasive surgery system
WO2017012624A1 (fr) 2015-07-21 2017-01-26 3Dintegrated Aps Kit de montage de canule, kit de montage de trocart, ensemble manchon, système de chirurgie mini-invasive et procédé afférent
DK178899B1 (en) 2015-10-09 2017-05-08 3Dintegrated Aps A depiction system
JP6729878B2 (ja) 2016-04-05 2020-07-29 ウシオ電機株式会社 多光子励起用スーパーコンティニウム光生成光源、多光子励起用スーパーコンティニウム光生成方法、多光子励起蛍光顕微鏡及び多光子励起方法
FR3067524B1 (fr) 2017-06-09 2019-07-26 Centre National De La Recherche Scientifique Dispositif et procede de microscopie multiphotonique

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4659952B2 (ja) * 2000-08-29 2011-03-30 独立行政法人科学技術振興機構 超解像顕微鏡
US6369928B1 (en) * 2000-11-01 2002-04-09 Optical Biopsy Technologies, Inc. Fiber-coupled, angled-dual-illumination-axis confocal scanning microscopes for performing reflective and two-photon fluorescence imaging
DE10120425C2 (de) * 2001-04-26 2003-12-18 Leica Microsystems Scanmikroskop
DE10151217B4 (de) * 2001-10-16 2012-05-16 Carl Zeiss Microlmaging Gmbh Verfahren zum Betrieb eines Laser-Scanning-Mikroskops
JP2009150649A (ja) * 2005-03-29 2009-07-09 Osaka Univ 空間情報検出装置
WO2007137060A2 (fr) * 2006-05-16 2007-11-29 Applied Biosystems Systèmes, procédés, et appareil destinés au séquençage d'une molécule unique
JP2008076361A (ja) * 2006-09-25 2008-04-03 Toshiba Corp 顕微鏡装置及び分析装置
EP2082463B1 (fr) * 2006-10-26 2019-05-15 Cornell Research Foundation, Inc. Système et procédé de production d'impulsions optiques d'une longueur d'onde voulue utilisant le rayonnement de cherenkov dans des fibres à mode d'ordre supérieur
WO2010071682A2 (fr) * 2008-12-20 2010-06-24 Purdue Research Foundation Plate-forme multimodale pour microscopie et microspectroscopie optiques non linéaires
JP2011141311A (ja) * 2010-01-05 2011-07-21 Nikon Corp 多光子顕微鏡
JP5437864B2 (ja) * 2010-03-10 2014-03-12 富士フイルム株式会社 ｐＨ測定装置の作動方法、検出装置の作動方法、及び生体物質分析装置の作動方法、並びに各装置

Also Published As

Publication number Publication date
FR2986668A1 (fr) 2013-08-09
EP2810050A1 (fr) 2014-12-10
WO2013113861A1 (fr) 2013-08-08
US20140367591A1 (en) 2014-12-18
JP6254096B2 (ja) 2017-12-27
JP2015511312A (ja) 2015-04-16

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