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FR2983077B1 - Seringue - Google Patents

Seringue Download PDF

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Publication number
FR2983077B1
FR2983077B1 FR1350671A FR1350671A FR2983077B1 FR 2983077 B1 FR2983077 B1 FR 2983077B1 FR 1350671 A FR1350671 A FR 1350671A FR 1350671 A FR1350671 A FR 1350671A FR 2983077 B1 FR2983077 B1 FR 2983077B1
Authority
FR
France
Prior art keywords
syringe
relates
present
small volume
ophthalmic injections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
FR1350671A
Other languages
English (en)
Other versions
FR2983077A1 (fr
Inventor
Juergen Sigg
Christophe Royer
Andrew Mark Bryant
Heinrich Martin Buettgen
Marie Picci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48051683&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2983077(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE202012011016U external-priority patent/DE202012011016U1/de
Priority claimed from AU2013100070A external-priority patent/AU2013100070B4/en
Application filed by Novartis AG filed Critical Novartis AG
Publication of FR2983077A1 publication Critical patent/FR2983077A1/fr
Application granted granted Critical
Publication of FR2983077B1 publication Critical patent/FR2983077B1/fr
Revoked legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104—Caps for syringes without needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M2005/3131—Syringe barrels specially adapted for improving sealing or sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
    • A61M2005/3139—Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508—Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0612—Eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513—Piston constructions to improve sealing or sliding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne une seringue, en particulier une seringue de petit volume telle qu'une seringue appropriée pour les injections ophtalmiques.
FR1350671A 2012-07-03 2013-01-25 Seringue Revoked FR2983077B1 (fr)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
EP12174860 2012-07-03
EP12174860.2 2012-07-03
EP12189649 2012-10-23
EP12189649.2 2012-10-23
DE202012011016U DE202012011016U1 (de) 2012-07-03 2012-11-16 Aflibercept-Spritze
AU2012101678A AU2012101678B4 (en) 2012-07-03 2012-11-16 Use of device
AU2012101677A AU2012101677B4 (en) 2012-07-03 2012-11-16 Device
DE202012011260U DE202012011260U1 (de) 2012-07-03 2012-11-23 Ranibizumab-Spritze
DE202012011259U DE202012011259U1 (de) 2012-07-03 2012-11-23 Bevacizumab-Spritze
EP12195360 2012-12-03
EP12195360.8 2012-12-03
AU2013100070A AU2013100070B4 (en) 2012-07-03 2013-01-23 Use of device
DE201320000688 DE202013000688U1 (de) 2012-07-03 2013-01-23 Glas-Spritze
AU2013100071A AU2013100071C4 (en) 2012-07-03 2013-01-23 Device

Publications (2)

Publication Number Publication Date
FR2983077A1 FR2983077A1 (fr) 2013-05-31
FR2983077B1 true FR2983077B1 (fr) 2018-09-14

Family

ID=48051683

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1350671A Revoked FR2983077B1 (fr) 2012-07-03 2013-01-25 Seringue

Country Status (40)

Country Link
US (1) US9220631B2 (fr)
EP (5) EP3685826B1 (fr)
JP (2) JP5744927B2 (fr)
KR (7) KR102395557B1 (fr)
CN (4) CN111249062A (fr)
AR (1) AR090059A1 (fr)
AU (1) AU2013201624A1 (fr)
BR (2) BR112014032990B1 (fr)
CA (1) CA2803566A1 (fr)
CH (1) CH706741B1 (fr)
CL (1) CL2014003619A1 (fr)
CO (1) CO7151483A2 (fr)
CY (2) CY1121497T1 (fr)
DE (1) DE202013000688U1 (fr)
DK (4) DK2869813T3 (fr)
EA (1) EA031583B1 (fr)
EC (1) ECSP15004005A (fr)
ES (4) ES2912848T3 (fr)
FR (1) FR2983077B1 (fr)
GT (1) GT201400300A (fr)
HK (1) HK1188404A1 (fr)
HR (4) HRP20220083T1 (fr)
HU (3) HUE055227T2 (fr)
IL (2) IL236296B (fr)
JO (2) JOP20200175A1 (fr)
LT (4) LT2869813T (fr)
MA (1) MA37740B2 (fr)
MX (1) MX358323B (fr)
MY (1) MY164536A (fr)
NZ (1) NZ702980A (fr)
PE (1) PE20150196A1 (fr)
PH (1) PH12014502785A1 (fr)
PL (4) PL3685826T3 (fr)
PT (1) PT2869813T (fr)
SG (1) SG11201408261UA (fr)
SI (4) SI2869813T1 (fr)
TN (1) TN2014000517A1 (fr)
TW (1) TWI632920B (fr)
WO (1) WO2014005728A1 (fr)
ZA (1) ZA201409411B (fr)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2995971A1 (fr) 2005-03-25 2006-10-05 Regeneron Pharmaceuticals, Inc. Formulations d'antagonistes du facteur vegf
JP5216002B2 (ja) 2006-06-16 2013-06-19 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 硝子体内投与に適したｖｅｇｆアンタゴニスト製剤
US11624115B2 (en) 2010-05-12 2023-04-11 Sio2 Medical Products, Inc. Syringe with PECVD lubrication
US9878101B2 (en) 2010-11-12 2018-01-30 Sio2 Medical Products, Inc. Cyclic olefin polymer vessels and vessel coating methods
WO2013071138A1 (fr) 2011-11-11 2013-05-16 Sio2 Medical Products, Inc. Revêtement de passivation, de protection de ph ou à pouvoir lubrifiant pour conditionnement pharmaceutique, processus et appareil de revêtement
US11116695B2 (en) 2011-11-11 2021-09-14 Sio2 Medical Products, Inc. Blood sample collection tube
CA3126069A1 (fr) 2012-06-01 2013-12-05 Novartis Ag Seringues
JOP20200175A1 (ar) 2012-07-03 2017-06-16 Novartis Ag حقنة
US20150297800A1 (en) 2012-07-03 2015-10-22 Sio2 Medical Products, Inc. SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS
US9764093B2 (en) 2012-11-30 2017-09-19 Sio2 Medical Products, Inc. Controlling the uniformity of PECVD deposition
KR102167557B1 (ko) 2013-03-11 2020-10-20 에스아이오2 메디컬 프로덕츠, 인크. 코팅된 패키징
US10251815B2 (en) * 2013-03-13 2019-04-09 Rush University Medical Center Delivery device and storage system for oropharyngeal administration of mother's colostrum and milk
US20140350518A1 (en) * 2013-05-23 2014-11-27 Allergan, Inc. Syringe extrusion accessory
US10010447B2 (en) 2013-12-18 2018-07-03 Novartis Ag Systems and methods for subretinal delivery of therapeutic agents
US11066745B2 (en) 2014-03-28 2021-07-20 Sio2 Medical Products, Inc. Antistatic coatings for plastic vessels
US20170232199A1 (en) * 2014-05-12 2017-08-17 Formycon Ag Pre-Filled Plastic Syringe Containing a VEGF Antagonist
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
TWI761959B (zh) 2014-11-07 2022-04-21 瑞士商諾華公司 治療眼部疾病之方法
EP3058974A1 (fr) 2015-02-19 2016-08-24 Sanofi-Aventis Deutschland GmbH Dispositif d'injection avec dispositif supplémentaire
WO2016150900A2 (fr) 2015-03-23 2016-09-29 Sanofi-Aventis Deutschland Gmbh Dispositif d'injection
MA41906A (fr) 2015-04-10 2018-02-13 Dompe Farm Spa Dispositif de distribution de gouttes oculaires
AU2016358111B2 (en) 2015-11-18 2021-11-18 Formycon Ag Pre-filled pharmaceutical package comprising a liquid formulation of a VEGF-antagonist
MX2018006139A (es) * 2015-11-18 2019-03-14 Sio2 Medical Products Inc Envase farmaceutico para formulaciones oftalmicas.
AU2016356047B2 (en) * 2015-11-18 2021-10-21 Formycon Ag Pre-filled plastic syringe containing a VEGF antagonist
IL295808B2 (en) 2015-12-03 2023-10-01 Regeneron Pharma Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-vegf
IL260323B2 (en) 2015-12-30 2025-01-01 Kodiak Sciences Inc Antibodies and their conjugates
CN109069754B (zh) * 2016-04-15 2021-09-07 参天制药株式会社 准确、精确的微升剂量注射器
US20170349313A1 (en) * 2016-06-01 2017-12-07 Centurion Medical Products Corporation Methods for manufacturing non-glass prefilled syringes
WO2017217544A1 (fr) 2016-06-17 2017-12-21 花王株式会社 Encre à base aqueuse
TWI737742B (zh) * 2016-06-22 2021-09-01 德商梅茲製藥有限兩合公司 肉毒桿菌毒素的預填充式注射器系統、具有其之套組以及其之使用
ITUA20162072A1 (it) * 2016-06-30 2017-12-30 Platinum Corp Srl Dropper a volume controllato
WO2018037467A1 (fr) 2016-08-22 2018-03-01 富士機械製造株式会社 Procédé de production de peroxyde d'hydrogène aqueux et procédé de stérilisation d'un objet à stériliser
US10537683B2 (en) 2016-11-03 2020-01-21 Johnson & Johnson Surgical Vision, Inc. Syringe finger grip
CA3056223A1 (fr) 2017-03-27 2018-10-04 Regeneron Pharmaceuticals, Inc. Methodes de sterilisation de produits medicaux et produits medicaux sterilises
JP2020516695A (ja) 2017-04-12 2020-06-11 ウリゲン ファーマシューティカルズ、インコーポレイテッド 改善された安定性を備えた注射器中に局所麻酔薬、緩衝液、およびグルコサミノグリカンを含む製品
US10898649B2 (en) 2017-05-05 2021-01-26 Alcon Inc. Syringe
US20200171244A1 (en) 2017-05-24 2020-06-04 Sio2 Medical Products, Inc. Sterilizable pharmaceutical package for ophthalmic formulations
EP3630043A1 (fr) 2017-05-24 2020-04-08 Formycon AG Conditionnements pharmaceutiques pré-remplis stérilisables comprenant une formulation liquide d'un antagoniste du vegf
US11090445B2 (en) 2017-06-16 2021-08-17 Credence Medsystems, Inc. System and method for safety syringe
US11590175B2 (en) 2017-08-23 2023-02-28 Merakris Therapeutics Llc Compositions containing amniotic components and methods for preparation and use thereof
FR3072297B1 (fr) * 2017-10-17 2023-05-12 Edix Sa Dispositif d'injection manuelle
CN117138171A (zh) 2017-12-13 2023-12-01 里珍纳龙药品有限公司 用于精确剂量输送的装置和方法
ES2974299T3 (es) 2018-02-02 2024-06-26 Hoffmann La Roche Jeringa precargada y procedimiento de esterilización de una jeringa precargada
KR20200140817A (ko) 2018-03-02 2020-12-16 코디악 사이언시스 인코포레이티드 Il-6 항체 그리고 이의 융합 작제물 및 접합체
WO2019199901A1 (fr) * 2018-04-09 2019-10-17 Sio2 Medical Products, Inc. Ensembles pistons étirables
CN115814202A (zh) * 2018-04-24 2023-03-21 W.L.戈尔及同仁股份有限公司 具有抑制氧气渗透的医疗递送设备
CN118948760A (zh) 2018-05-10 2024-11-15 瑞泽恩制药公司 含有高浓度vegf受体融合蛋白的制剂
US11519020B2 (en) 2018-05-25 2022-12-06 Regeneron Pharmaceuticals, Inc. Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF
US20210260300A1 (en) * 2018-06-01 2021-08-26 Sun Pharma Advanced Research Company Limited An injection device
EP3870119A4 (fr) * 2018-10-26 2022-07-20 Singapore Health Services Pte. Ltd. Dispositif et procédé d'extraction et d'injection ophtalmiques
WO2020102444A1 (fr) 2018-11-13 2020-05-22 Credence Medsystems, Inc. Système et procédé pour l'injection de microdoses
WO2020109344A1 (fr) 2018-11-29 2020-06-04 F. Hoffmann-La Roche Ag Dispositif d'administration oculaire pour oligonucléotides antisens
WO2020109343A1 (fr) 2018-11-29 2020-06-04 F. Hoffmann-La Roche Ag Polythérapie pour le traitement de la dégénérescence maculaire
CR20210318A (es) 2018-12-18 2021-07-14 Novartis Ag Formulación de solución de proteínas que contiene una alta concentración de un anticuerpo anti-vegf
CN110721026A (zh) * 2018-12-21 2020-01-24 南通市第一人民医院 一种眼科手术用取硅油装置防滑层的制备方法
EP3689397A1 (fr) * 2019-01-31 2020-08-05 SCHOTT Schweiz AG Corps de seringue, seringue et dispositif d'injection permettant d'injecter un milieu à haute viscosité
GB201902355D0 (en) * 2019-02-21 2019-04-10 New Injection Systems Ltd Modular auto injector
FR3093004B1 (fr) * 2019-02-21 2023-04-07 Dev Techniques Plastiques Procede de preparation d’une seringue
PT3960702T (pt) * 2019-03-29 2023-07-07 Kortuc Inc Utilização de uma composição de óleo compreendendo óleo de silicone para estabilizar o armazenamento de peróxido de hidrogénio
BR112021020849A2 (pt) 2019-04-18 2021-12-14 Boehringer Ingelheim Int Dispositivo de administração para administração de um fluido
MX2021014622A (es) 2019-06-05 2022-01-06 Regeneron Pharma Dispositivos y metodos para administracion de dosis de precision.
US20220265825A1 (en) * 2019-08-01 2022-08-25 Gennova Biopharmaceuticals Limited Opthalmic composition of bevacizumab
WO2021046070A1 (fr) 2019-09-03 2021-03-11 Amgen Inc. Dispositif d'injection destiné à l'administration de médicament et emballage destiné au dispositif d'injection
AU2020348947A1 (en) 2019-09-16 2022-03-10 Amgen Inc. Method for external sterilization of drug delivery device
CN114786731A (zh) 2019-10-10 2022-07-22 科达制药股份有限公司 治疗眼部病症的方法
US11690960B2 (en) 2019-11-14 2023-07-04 Congruence Medical Solutions, Llc Variable dosing syringe
EP4069164A2 (fr) 2019-12-05 2022-10-12 F. Hoffmann-La Roche AG Seringue et procédé de test d'étanchéité
KR102727299B1 (ko) * 2019-12-12 2024-11-08 노파르티스 아게 주입 장치 및 주입 용액 전달 시스템
CN114929311B (zh) * 2020-03-24 2023-07-28 泰尔茂株式会社 注射器筒体用握把以及筒体组装体和注射器
US11883635B2 (en) 2020-06-17 2024-01-30 Credence MedSystems System and method for microdose injection
MX2023004995A (es) 2020-10-30 2023-05-12 Boehringer Ingelheim Int Dispositivo de administracion para, en particular, la administracion intravitrea de un fluido.
EP4255530A1 (fr) 2020-12-01 2023-10-11 Boehringer Ingelheim International GmbH Dispositif d'administration destiné, en particulier, à l'administration intravitréenne d'un fluide
KR102720956B1 (ko) 2020-12-15 2024-10-24 삼천당제약주식회사 안과용 제형을 포함하는 시린지
CN116782969A (zh) * 2020-12-29 2023-09-19 W.L.戈尔及同仁股份有限公司 具有薄膜润滑剂的药物注射止挡件
JP2024515616A (ja) * 2021-04-15 2024-04-10 アルテオジェン・インコーポレイテッド 低容量薬液充填の事前充填型注射器及びその製造方法
CN114146220B (zh) 2022-02-10 2022-04-29 中国远大集团有限责任公司 一种包含无菌pcl微球的美容产品
WO2024137753A1 (fr) 2022-12-20 2024-06-27 W. L. Gore & Associates, Inc. Butoirs de seringue à faible force d'insertion, ensembles et procédés associés
EP4480517A1 (fr) 2023-06-20 2024-12-25 Ypsomed AG Auto-injecteur pour injection intravitréenne
ES2998138A2 (es) * 2023-07-28 2025-02-19 Novartis Ag Nuevos usos del omalizumab
CN117942456B (zh) * 2024-03-27 2024-07-12 山东永聚医药科技股份有限公司 缓释型非牛顿流体制剂用预灌封注射器及其制备工艺

Family Cites Families (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US31789A (en) 1861-03-26 Bread-slicebi
DE2629557B2 (de) 1976-07-01 1980-05-14 Paul E. Dr.Med. 8000 Muenchen Doerr Einmai-Injektionsspritze
JPH0747045B2 (ja) * 1986-10-15 1995-05-24 株式会社大協精工 積層した注射器用滑栓
US4946441A (en) 1988-07-21 1990-08-07 Maurice Laderoute Limited use hypodermic syringe
JPH0725963Y2 (ja) 1989-11-06 1995-06-14 清坤 曽 緊急避難装置
EP0511402B1 (fr) * 1990-11-17 1997-09-10 Santen Seiyaku Kabushiki Kaisha Cylindre de seringue a deux chambres
US5236604A (en) * 1991-05-29 1993-08-17 Sherwood Medical Company Serum separation blood collection tube and the method of using thereof
JP3186422B2 (ja) 1993-05-14 2001-07-11 武田薬品工業株式会社 プラスチゾル
US5405326A (en) 1993-08-26 1995-04-11 Habley Medical Technology Corporation Disposable safety syringe with retractable shuttle for luer lock needle
US5795337A (en) 1994-02-14 1998-08-18 Becton Dickinson And Company Syringe assembly and syringe stopper
US5688252A (en) 1994-09-30 1997-11-18 Takeda Chemical Industries, Ltd. Syringe
US5667495A (en) 1995-04-21 1997-09-16 Becton Dickinson France S.A. Backstop device for a syringe
US5607400A (en) * 1995-05-19 1997-03-04 Becton, Dickinson And Company Pre-fillable syringe and stopper assembly therefor
DE19622283A1 (de) 1996-05-23 1997-11-27 Schering Ag Verfahren zur terminalen Sterilisierung von befüllten Spritzen
JP4078406B2 (ja) * 1997-01-22 2008-04-23 有限会社コーキ・エンジニアリング 注射器のシリンダの製造方法
CN100480269C (zh) 1997-04-07 2009-04-22 基因技术股份有限公司 抗-血管内皮生长因子的抗体
JP3387775B2 (ja) * 1997-05-22 2003-03-17 株式会社大協精工 注射器用密封栓及びプレフィルド注射器
US6200627B1 (en) * 1998-03-17 2001-03-13 Becton, Dickinson And Company Low silicone glass prefillable syringe
JP2002515268A (ja) * 1998-04-30 2002-05-28 アボット・ラボラトリーズ 注射器アセンブリ
USD430015S (en) 1998-06-11 2000-08-29 Pharmacia & Upjohn Ab Blister pack for a syringe
JP2001104480A (ja) * 1999-10-05 2001-04-17 Daikyo Seiko Ltd プラスチック製プレフィルド注射器の密封に使用するゴム製ピストン
JP2001340455A (ja) 2000-05-31 2001-12-11 Yoshino Kogyosho Co Ltd シリンジ容器
JP2002177388A (ja) 2000-12-15 2002-06-25 Daikyo Seiko Ltd 医薬・医療用既充填注射器
JP2002241264A (ja) * 2001-02-19 2002-08-28 Asahi Kasei Corp エルカトニンのプレフィルドシリンジ製剤
US20050154354A1 (en) * 2001-12-27 2005-07-14 Yoshihiko Kawasaki Cartridge syringe, cartridge and ophthalmologic syringe set having such syringe
JP4141156B2 (ja) * 2002-03-15 2008-08-27 日本ベクトン・ディッキンソン株式会社 プランジャ後退制限機構付きプレフィルドシリンジ
US6688252B1 (en) 2002-12-11 2004-02-10 Gary Caravella Boat cover
EP1596909A2 (fr) 2003-02-27 2005-11-23 Baxter International Inc. Ensemble piston pour seringue
JP2004313369A (ja) 2003-04-15 2004-11-11 Menicon Co Ltd カートリッジ注入器、カートリッジ及び該注入器を備えた眼科用注入器セット
FR2855413B1 (fr) 2003-05-26 2005-12-30 Becton Dickinson France Seringue pre-remplie avec coiffe anti effraction
US7967772B2 (en) * 2004-01-12 2011-06-28 Iscience Interventional Corporation Injector for viscous materials
US8124207B2 (en) 2004-03-02 2012-02-28 Sakhrani Vinay G Article with lubricated surface and method
JP4680997B2 (ja) 2004-06-08 2011-05-11 ツェンドゥー カンホン バイオテクノロジーズ カンパニー リミテッド 血管新生を阻害するキメラタンパク質およびその利用
PT1802334E (pt) 2004-10-21 2012-11-28 Genentech Inc Método para tratamento de doenças neovasculares intraoculares
EP1877438A2 (fr) * 2005-02-02 2008-01-16 Regeneron Pharmaceuticals, Inc. Methode de traitement de lesion oculaire par l'administration locale d'un inhibiteur de vegf
WO2006128564A1 (fr) 2005-05-31 2006-12-07 Baxter International Inc. Cylindre creux en polypropylene pourvu d'un piston en caoutchouc coulissant
US20060293270A1 (en) * 2005-06-22 2006-12-28 Adamis Anthony P Methods and compositions for treating ocular disorders
US20070060887A1 (en) * 2005-08-22 2007-03-15 Marsh David A Ophthalmic injector
FR2890316B1 (fr) * 2005-09-02 2007-10-05 Aguettant Soc Par Actions Simp Seringue destinee a etre remplie puis sterilisee par autoclavage a la vapeur.
JP2009508593A (ja) * 2005-09-16 2009-03-05 （オーエスアイ）アイテツク・インコーポレーテツド 眼科用シリンジ
WO2007035623A1 (fr) 2005-09-17 2007-03-29 Technology Group Northwest Inc. Systeme et methode pour une protection dirigee contre des attaques d'injection de code dans un dispositif informatique
US8168584B2 (en) 2005-10-08 2012-05-01 Potentia Pharmaceuticals, Inc. Methods of treating age-related macular degeneration by compstatin and analogs thereof
ZA200803814B (en) * 2005-10-14 2010-02-24 Alcon Inc Method for treating primary and secondary forms of glaucoma
AT502791B1 (de) * 2006-04-06 2007-05-15 Pharma Consult Ges M B H & Co Injektionsspritze
TW200806315A (en) * 2006-04-26 2008-02-01 Wyeth Corp Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
MX2008014136A (es) * 2006-05-04 2009-03-31 Fovea Pharmaceuticals Sa Combinacion que comprende un inhibidor de factor de crecimiento endotelial vascular y serina proteasa para tratar enfermedades neovasculares.
JP5216002B2 (ja) 2006-06-16 2013-06-19 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 硝子体内投与に適したｖｅｇｆアンタゴニスト製剤
JP4131001B2 (ja) 2006-07-28 2008-08-13 大成化工株式会社 定量吐出装置
CN200973886Y (zh) * 2006-11-20 2007-11-14 骆忠林 一种注射器
WO2008077155A1 (fr) 2006-12-21 2008-06-26 Genentech, Inc. Stérilisation d'objets contenant des molécules biologiques
US8529521B2 (en) 2007-04-23 2013-09-10 Ultimed Inc. Low-dosage syringe
CN100563736C (zh) * 2007-06-02 2009-12-02 丁锐 一次性防刺伤注射器
US7972303B2 (en) 2007-06-12 2011-07-05 Becton, Dickinson And Company Syringe with disabling mechanism
ATE535261T1 (de) * 2007-07-31 2011-12-15 Al Chi Mi A S R L Methode zum herstellen einer vorrichtung für ophthalmische behandlungen
WO2009030975A1 (fr) 2007-09-03 2009-03-12 Becton Dickinson France Dispositif médical comprenant une chambre siliconée et un moyen de fermeture pourvu d'un revêtement
WO2009030976A1 (fr) 2007-09-03 2009-03-12 Becton Dickinson France Dispositif médical et revêtement lisse pour ce dispositif
DE102008005938A1 (de) * 2008-01-24 2009-07-30 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Vorgefüllte Spritze und Verfahren zum Verpacken einer Spritze
JP5352907B2 (ja) 2008-01-24 2013-11-27 メフレックス テレコントロール ゲーエムベーハー ウント ツェーオー． カーゲー 駆動ケーブル用のエンドキャップ、駆動ケーブル、エンドキャップの製造方法、および、駆動ケーブルの製造方法
EP2249801A2 (fr) 2008-02-07 2010-11-17 Amgen Inc. Compositions protéiniques stabilisées
CN102065939B (zh) * 2008-06-17 2013-06-19 电气化学工业株式会社 注射器
WO2009158613A1 (fr) 2008-06-26 2009-12-30 West Pharmaceutical Services, Inc. Procédé de revêtement de polyxylylène sur des surfaces fluoropolymères et dispositifs ainsi enduits
US8221353B2 (en) 2008-10-21 2012-07-17 KMG Pharma, Inc Intravitreal injection device and system
CN107011425B (zh) 2008-11-03 2021-01-01 分子组合公司 抑制vegf-a受体相互作用的结合蛋白
CN102231994B (zh) * 2008-12-03 2014-04-23 电气化学工业株式会社 注射器
WO2010127029A1 (fr) * 2009-05-01 2010-11-04 Ophthotech Corporation Procédés de traitement ou de prévention de maladies ophtalmologiques
CA2763469A1 (fr) * 2009-05-28 2010-12-02 Glaxo Group Limited Proteines de liaison a l'antigene
EP2266647A1 (fr) * 2009-06-25 2010-12-29 Sanofi-Aventis Deutschland GmbH Mécanisme d'entraînement pour dispositif d'administration de médicament
AR078060A1 (es) 2009-07-14 2011-10-12 Novartis Ag Descontaminacion de superficie de contenedores previamente llenados en empaque secundario
EP3556412B1 (fr) 2009-10-29 2021-04-14 W.L. Gore & Associates Inc. Piston de seringue revêtu d'eptfe
CN201578690U (zh) 2010-01-21 2010-09-15 王建友 一种注射器
US9408746B2 (en) 2010-03-31 2016-08-09 Ocuject, Llc Device and method for intraocular drug delivery
CA2795096C (fr) 2010-03-31 2021-10-26 Ocuject, Llc Dispositif et procede pour administrer un medicament par voie intra-oculaire
TWI510246B (zh) 2010-04-30 2015-12-01 Molecular Partners Ag 抑制ｖｅｇｆ－ａ受體交互作用的經修飾結合性蛋白質
JP2012045046A (ja) 2010-08-24 2012-03-08 Gc Corp 歯科用シリンジ
FR2966044B1 (fr) 2010-10-18 2012-11-02 Sanofi Pasteur Procede de conditionnement d'un vaccin contenant un adjuvant d'aluminium
CN103415313B (zh) 2011-03-01 2017-06-13 泰尔茂株式会社 注射器及注射器组装体
KR101978235B1 (ko) 2011-04-25 2019-05-15 아이콘 바이오사이언스, 인크. 주사기용 투여량 가이드
US20130012918A1 (en) 2011-07-07 2013-01-10 Gary Foster Steady grip ophthalmic surgical syringe and method
CN103957966B (zh) 2011-09-27 2017-09-29 贝克顿迪金森法国公司 等离子体处理过的硅油作为医用注射装置中的涂层的用途
US9421129B2 (en) 2012-04-02 2016-08-23 Ocuject, Llc Intraocular delivery devices and methods therefor
US10780228B2 (en) 2012-05-07 2020-09-22 Medline Industries, Inc. Prefilled container systems
CA3126069A1 (fr) 2012-06-01 2013-12-05 Novartis Ag Seringues
AU2012101677B4 (en) 2012-07-03 2012-12-20 Novartis Ag Device
JOP20200175A1 (ar) 2012-07-03 2017-06-16 Novartis Ag حقنة
AU2013100070B4 (en) * 2012-07-03 2013-04-04 Novartis Ag Use of device
US9662450B2 (en) * 2013-03-01 2017-05-30 Sio2 Medical Products, Inc. Plasma or CVD pre-treatment for lubricated pharmaceutical package, coating process and apparatus

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