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FR2952368B1 - Particule de silice incorporant une molecule d'interet, son procede de preparation et ses utilisations. - Google Patents

Particule de silice incorporant une molecule d'interet, son procede de preparation et ses utilisations.

Info

Publication number
FR2952368B1
FR2952368B1 FR0957920A FR0957920A FR2952368B1 FR 2952368 B1 FR2952368 B1 FR 2952368B1 FR 0957920 A FR0957920 A FR 0957920A FR 0957920 A FR0957920 A FR 0957920A FR 2952368 B1 FR2952368 B1 FR 2952368B1
Authority
FR
France
Prior art keywords
interest
molecule
preparing
same
silica particle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0957920A
Other languages
English (en)
Other versions
FR2952368A1 (fr
Inventor
Aurelien Auger
Olivier Raccurt
Olivier Jean Christian Poncelet
Jorice Samuel
Sylvie Sauvaigo
Chloe Schubert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR0957920A priority Critical patent/FR2952368B1/fr
Priority to US13/508,698 priority patent/US20120283379A1/en
Priority to EP10779753A priority patent/EP2498761A1/fr
Priority to PCT/EP2010/067190 priority patent/WO2011058046A1/fr
Publication of FR2952368A1 publication Critical patent/FR2952368A1/fr
Application granted granted Critical
Publication of FR2952368B1 publication Critical patent/FR2952368B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/06Making microcapsules or microballoons by phase separation
    • B01J13/14Polymerisation; cross-linking
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5115Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00Silicon; Compounds thereof
    • C01B33/113Silicon oxides; Hydrates thereof
    • C01B33/12Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • C01B33/18Preparation of finely divided silica neither in sol nor in gel form; After-treatment thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Silicon Compounds (AREA)
FR0957920A 2009-11-10 2009-11-10 Particule de silice incorporant une molecule d'interet, son procede de preparation et ses utilisations. Expired - Fee Related FR2952368B1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR0957920A FR2952368B1 (fr) 2009-11-10 2009-11-10 Particule de silice incorporant une molecule d'interet, son procede de preparation et ses utilisations.
US13/508,698 US20120283379A1 (en) 2009-11-10 2010-11-10 Silica particle including a molecule of interest, method for preparing same and uses thereof
EP10779753A EP2498761A1 (fr) 2009-11-10 2010-11-10 Particule de silice incorporant une molecule d'interet, son procede de preparation et ses utilisations
PCT/EP2010/067190 WO2011058046A1 (fr) 2009-11-10 2010-11-10 Particule de silice incorporant une molecule d'interet, son procede de preparation et ses utilisations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0957920A FR2952368B1 (fr) 2009-11-10 2009-11-10 Particule de silice incorporant une molecule d'interet, son procede de preparation et ses utilisations.

Publications (2)

Publication Number Publication Date
FR2952368A1 FR2952368A1 (fr) 2011-05-13
FR2952368B1 true FR2952368B1 (fr) 2012-01-13

Family

ID=42244525

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0957920A Expired - Fee Related FR2952368B1 (fr) 2009-11-10 2009-11-10 Particule de silice incorporant une molecule d'interet, son procede de preparation et ses utilisations.

Country Status (4)

Country Link
US (1) US20120283379A1 (fr)
EP (1) EP2498761A1 (fr)
FR (1) FR2952368B1 (fr)
WO (1) WO2011058046A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9023650B2 (en) * 2009-11-02 2015-05-05 Lawrence Livermore National Security, Llc DNA tagged microparticles
KR101411793B1 (ko) * 2011-05-23 2014-06-24 고려대학교 산학협력단 실리카 캡슐화된 단분자 나노효소입자 제조방법 및 이를 통해 제조된 단분자 나노효소입자
US10322194B2 (en) 2012-08-31 2019-06-18 Sloan-Kettering Institute For Cancer Research Particles, methods and uses thereof
JP6465811B2 (ja) 2012-12-19 2019-02-06 スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ 多様式の粒子、方法およびその使用
JP6635791B2 (ja) 2013-02-20 2020-01-29 スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ 広視野ラマン撮像装置および関連方法
US9803230B2 (en) * 2013-03-15 2017-10-31 Abbott Molecular Inc. One-step procedure for the purification of nucleic acids
PT107002A (pt) * 2013-06-12 2014-12-12 Ecoticket Lda Processo para a obtenção de nanopartículas de sílica incorporando produtos hidrofílicos ou miscíveis em água e processo para a sua imobilização e encapsulamento quando aplicadas a fibras têxteis
US11266968B2 (en) 2013-09-16 2022-03-08 The University Of Queensland Mineralizing biosurfactant used for nucleating silica
US10912947B2 (en) 2014-03-04 2021-02-09 Memorial Sloan Kettering Cancer Center Systems and methods for treatment of disease via application of mechanical force by controlled rotation of nanoparticles inside cells
CN107072951A (zh) 2014-07-22 2017-08-18 雷莫内克斯生物制药有限公司 用于递送生物活性物质或蛋白质的组合物及其用途
CN106687146A (zh) 2014-07-28 2017-05-17 纪念斯隆-凯特琳癌症中心 作为医学同位素的通用结合剂的(类)金属硫族纳米粒子
US10577654B2 (en) * 2015-04-20 2020-03-03 Eth Zurich Particulate distributed sensing elements
DE102015108803A1 (de) * 2015-06-03 2016-12-08 Leibniz-Institut Für Neue Materialien Gemeinnützige Gmbh Verfahren zur Herstellung von modifizierten Nanopartikeln
CA2990223A1 (fr) 2015-07-01 2017-01-05 Memorial Sloan Kettering Cancer Center Particules anisotropes, leurs procedes et leurs utilisations
SG11201907260PA (en) 2017-02-06 2019-09-27 Lemonex Inc Physiologically active substance carrier
CN111132666B (zh) * 2017-07-25 2022-11-04 雷莫内克斯生物制药有限公司 用于将生理活性成分递送至血管的组合物
US11530132B2 (en) 2017-09-05 2022-12-20 Lemonex Inc. Composition comprising porous silica particles carrying a cell fate modulating factor
US11193368B2 (en) * 2018-04-27 2021-12-07 Ypf Tecnologia S.A. Nanotracer for oil recovery comprising an occluded polynucleotide and method of preparation thereof
EP3594290A1 (fr) * 2018-07-13 2020-01-15 Haelixa GmbH Éléments marqués et procédés de vérification
CN109761240A (zh) * 2019-03-19 2019-05-17 大连大学 一种氨基化二氧化硅颗粒的制备方法
CN115215348B (zh) * 2022-08-29 2023-11-17 吉林大学 一种蠕虫状的介孔二氧化硅的制备方法
CN116637593A (zh) * 2023-05-15 2023-08-25 宁波大学 一种可快速大容量吸附有机染料的高有机基团含量吸附剂及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2598558C (fr) * 2005-02-14 2013-04-02 Australian Nuclear Science & Technology Organisation Nanoparticules en couches
KR101205481B1 (ko) * 2005-06-17 2012-11-27 오스트레일리언뉴클리어사이언스앤드테크놀로지오거나이제이션 방출 가능한 도펀트를 함유한 입자
KR100845008B1 (ko) * 2006-08-09 2008-07-08 한국생명공학연구원 표면에 나노 구멍 또는 기공을 가지는 실리카 캡슐 및 그제조방법
WO2009078924A2 (fr) * 2007-12-06 2009-06-25 The Regents Of The University Of California Nanoparticules de silice mésoporeuse pour des applications biomédicales

Also Published As

Publication number Publication date
US20120283379A1 (en) 2012-11-08
WO2011058046A1 (fr) 2011-05-19
EP2498761A1 (fr) 2012-09-19
FR2952368A1 (fr) 2011-05-13

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Legal Events

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ST Notification of lapse

Effective date: 20150731