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FR2877011B1 - Souche de levure genetiquement modifiee presentant une production et une excretion accrue de s-adenosylmethionine (sam) - Google Patents

Souche de levure genetiquement modifiee presentant une production et une excretion accrue de s-adenosylmethionine (sam)

Info

Publication number
FR2877011B1
FR2877011B1 FR0411454A FR0411454A FR2877011B1 FR 2877011 B1 FR2877011 B1 FR 2877011B1 FR 0411454 A FR0411454 A FR 0411454A FR 0411454 A FR0411454 A FR 0411454A FR 2877011 B1 FR2877011 B1 FR 2877011B1
Authority
FR
France
Prior art keywords
adenosylmethionine
sam
excretion
genetically modified
yeast strain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0411454A
Other languages
English (en)
Other versions
FR2877011A1 (fr
Inventor
Dominique Thomas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR0411454A priority Critical patent/FR2877011B1/fr
Priority to JP2007538468A priority patent/JP2008517614A/ja
Priority to PCT/FR2005/002670 priority patent/WO2006045953A1/fr
Priority to EP05815142A priority patent/EP1805301A1/fr
Priority to US11/666,289 priority patent/US20100150871A1/en
Publication of FR2877011A1 publication Critical patent/FR2877011A1/fr
Application granted granted Critical
Publication of FR2877011B1 publication Critical patent/FR2877011B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/14—Yeasts or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/0102—Adenosine kinase (2.7.1.20)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Neurosurgery (AREA)
  • Pregnancy & Childbirth (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
FR0411454A 2004-10-27 2004-10-27 Souche de levure genetiquement modifiee presentant une production et une excretion accrue de s-adenosylmethionine (sam) Expired - Fee Related FR2877011B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR0411454A FR2877011B1 (fr) 2004-10-27 2004-10-27 Souche de levure genetiquement modifiee presentant une production et une excretion accrue de s-adenosylmethionine (sam)
JP2007538468A JP2008517614A (ja) 2004-10-27 2005-10-26 Ｓ−アデノシルメチオニン（ｓａｍ）の生産と分泌の増加を示す遺伝子修飾酵母株
PCT/FR2005/002670 WO2006045953A1 (fr) 2004-10-27 2005-10-26 Souche de levure genetiquement modifiee presentant une production et une excretion accrue de s-adenosylmethionine (sam)
EP05815142A EP1805301A1 (fr) 2004-10-27 2005-10-26 Souche de levure génétiquement modifiée présentant une production et une excrétion accrue de s-adénosylméthionine (sam)
US11/666,289 US20100150871A1 (en) 2004-10-27 2005-10-26 Genetically-modified strain of yeast with an increased production and output of s-adenosylmethionine (sam)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0411454A FR2877011B1 (fr) 2004-10-27 2004-10-27 Souche de levure genetiquement modifiee presentant une production et une excretion accrue de s-adenosylmethionine (sam)

Publications (2)

Publication Number Publication Date
FR2877011A1 FR2877011A1 (fr) 2006-04-28
FR2877011B1 true FR2877011B1 (fr) 2010-08-27

Family

ID=34950429

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0411454A Expired - Fee Related FR2877011B1 (fr) 2004-10-27 2004-10-27 Souche de levure genetiquement modifiee presentant une production et une excretion accrue de s-adenosylmethionine (sam)

Country Status (5)

Country Link
US (1) US20100150871A1 (fr)
EP (1) EP1805301A1 (fr)
JP (1) JP2008517614A (fr)
FR (1) FR2877011B1 (fr)
WO (1) WO2006045953A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2712368A4 (fr) * 2011-04-22 2015-04-29 Internat Park Of Creativity Capteurs de glucose et d'insuline et leurs procédés d'utilisation
US20150247174A1 (en) * 2012-12-28 2015-09-03 Anhui Huaheng Bioengineering Co., Ltd, Engineering bacteria for producing dl-alanine and method for producing dl-alanine by using engineering bacteria
CN103224917B (zh) * 2013-04-28 2014-06-04 北京凯因科技股份有限公司 一种恢复SAMe合成酶活力的方法
US10513711B2 (en) 2014-08-13 2019-12-24 Dupont Us Holding, Llc Genetic targeting in non-conventional yeast using an RNA-guided endonuclease
CN105483190B (zh) * 2015-10-23 2019-08-13 山东金城生物药业有限公司 酿酒酵母基因工程改造提高s-腺苷-l-蛋氨酸产量的方法
WO2018195273A1 (fr) * 2017-04-19 2018-10-25 The Corporation Of Mercer University Protéine sam-1, composition et méthodes d'utilisation
EP3428282A1 (fr) * 2017-07-11 2019-01-16 Alderys Une levure produisant de l'ectoine
WO2019011942A1 (fr) 2017-07-11 2019-01-17 Adisseo France S.A.S. Levure produisant de la méthionine
WO2023108505A1 (fr) * 2021-12-15 2023-06-22 中国科学院大连化学物理研究所 Procédé d'amélioration de l'alimentation en cofacteur sam de saccharomyces cerevisiae, levure modifiée et son utilisation
CN116262930A (zh) * 2021-12-15 2023-06-16 中国科学院大连化学物理研究所 一种提高酿酒酵母sam辅因子供应的方法、工程菌及其应用
CN115058350B (zh) * 2022-04-28 2023-12-01 湖南成大生物科技有限公司 一种引入钾离子转运体提高s-腺苷甲硫氨酸产量的方法

Also Published As

Publication number Publication date
WO2006045953A1 (fr) 2006-05-04
EP1805301A1 (fr) 2007-07-11
JP2008517614A (ja) 2008-05-29
FR2877011A1 (fr) 2006-04-28
US20100150871A1 (en) 2010-06-17

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20130628